How I Approach Laryngopharyngoesophageal Reflux (LPR)

Kaleigh Stabenau; Nikki Johnston

doi:10.1007/s11894-021-00823-4

How I Approach Laryngopharyngoesophageal Reflux (LPR)

Curr Gastroenterol Rep. 2021 Nov 19;23(12):27. doi: 10.1007/s11894-021-00823-4.

Authors

Kaleigh Stabenau¹, Nikki Johnston²

Affiliations

¹ Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI, 53226, USA.
² Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 W Wisconsin Ave, Milwaukee, WI, 53226, USA. njohnston@mcw.edu.

PMID: 34799757
DOI: 10.1007/s11894-021-00823-4

Abstract

The purpose of this article is to review the cornerstone and most recent literature regarding laryngopharynoesophageal reflux (LPR) including epidemiological characteristics, pathophysiology, symptoms, diagnosis, and management. The role of pepsin in the pathophysiology of LPR is highlighted in addition to new diagnostic modalities and pharmacologic therapies that target pepsin.

Publication types

Review

MeSH terms

Humans
Laryngopharyngeal Reflux* / diagnosis
Laryngopharyngeal Reflux* / epidemiology
Laryngopharyngeal Reflux* / therapy
Pepsin A

Substances

Pepsin A