Holmium complex with phospholipids as 1H NMR temperature probe for membrane systems

O Yu Selyutina; V E Koshman; M V Zelikman; S P Babailov

doi:10.1007/s10534-022-00388-3

Holmium complex with phospholipids as ¹H NMR temperature probe for membrane systems

Biometals. 2022 Jun;35(3):629-637. doi: 10.1007/s10534-022-00388-3. Epub 2022 Mar 24.

Authors

O Yu Selyutina¹, V E Koshman², M V Zelikman³, S P Babailov⁴

Affiliations

¹ Institute of Chemical Kinetics and Combustion, Institutskaya St., 3, Novosibirsk, Russia, 630090. olga.gluschenko@gmail.com.
² Institute of Chemical Kinetics and Combustion, Institutskaya St., 3, Novosibirsk, Russia, 630090.
³ Institute of Solid-State Chemistry and Mechanochemistry, Kutateladze St., 18, Novosibirsk, Russia, 630128.
⁴ A.V. Nikolaev Institute of Inorganic Chemistry, The Siberian Branch of the Russian Academy of Sciences, Av. Lavrentyev 3, Novosibirsk, Russia, 630090.

PMID: 35325368
DOI: 10.1007/s10534-022-00388-3

Abstract

The temperature dependence of the lanthanide-induced chemical shifts (LISs) was studied for the systems containing 1-palmitoyl-2-oleoylphosphatidylcholine (POPC)-Ho, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-Ho and 1,2-dimyristoyl-sn-glycero-3-phosphorylcholine (DMPC)-Ho in unilamellar liposomes. In the POPC-Ho system, anti-Curie dependence of LISs is observed, same as previously observed in POPC-Pr system. In the DPPC- and DMPC-Ho systems, temperature features are observed which are probably connected with phase transition.

Keywords: Lanthanides; Lipid membrane; Membrane temperature sensor; NMR; Paramagnetic shift.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Dimyristoylphosphatidylcholine* / chemistry
Holmium
Phospholipids* / chemistry
Proton Magnetic Resonance Spectroscopy
Temperature

Substances

Phospholipids
Dimyristoylphosphatidylcholine
Holmium