Aldose reductase inhibitors: a potential new class of agents for the pharmacological control of certain diabetic complications

MeSH terms

• Aldehyde Reductase / antagonists & inhibitors*
• Aldehyde Reductase / metabolism
• Animals
• Binding Sites
• Blood Glucose / metabolism
• Cataract / drug therapy
• Chemical Phenomena
• Chemistry
• Corneal Diseases / drug therapy
• Diabetes Complications*
• Diabetes Mellitus / drug therapy
• Diabetes Mellitus / metabolism
• Diabetic Angiopathies / drug therapy
• Diabetic Nephropathies / drug therapy
• Diabetic Neuropathies / drug therapy
• Diabetic Retinopathy / drug therapy
• Disease Models, Animal
• Fluorenes / therapeutic use
• Galactose / metabolism
• Humans
• Hydantoins / therapeutic use
• Imidazoles / therapeutic use
• Imidazolidines*
• Models, Molecular
• Naphthalenes / therapeutic use
• Phthalazines / therapeutic use
• Rhodanine / analogs & derivatives
• Rhodanine / therapeutic use
• Sorbitol / metabolism
• Structure-Activity Relationship
• Substrate Specificity
• Sugar Alcohol Dehydrogenases / antagonists & inhibitors*
• Thiazolidines
• Tissue Distribution