Design, synthesis, and broad spectrum antiviral activity of 1- -D-ribofuranosyl-1,2,4-triazole-3-carboxamide and related nucleosides

J Med Chem. 1972 Nov;15(11):1150-4. doi: 10.1021/jm00281a014.
No abstract available

MeSH terms

  • Animals
  • Antiviral Agents / chemical synthesis*
  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • Carbamates / chemical synthesis
  • Carbamates / pharmacology
  • Carbamates / therapeutic use
  • Cricetinae
  • Cytopathogenic Effect, Viral
  • DNA Viruses / drug effects
  • Encephalomyelitis, Equine / drug therapy
  • Herpes Simplex / drug therapy
  • Mice
  • Orthomyxoviridae Infections / drug therapy
  • Paramyxoviridae Infections / drug therapy
  • RNA Viruses / drug effects
  • Rabbits
  • Ribonucleosides / chemical synthesis*
  • Ribonucleosides / pharmacology
  • Ribonucleosides / therapeutic use
  • Triazoles / chemical synthesis*
  • Triazoles / pharmacology
  • Triazoles / therapeutic use
  • Vaccinia / drug therapy
  • Virus Replication / drug effects

Substances

  • Antiviral Agents
  • Carbamates
  • Ribonucleosides
  • Triazoles