The hapten-carrier effect in teleost fish

J Immunol. 1975 Mar;114(3):925-7.

Abstract

The sea robin (Prionotus evolans), a representative teleost fish, was found to undergo the hapten-carrier effect, suggestive of T-B cell cooperativity, in vivo with dinitrophenyl as the hapten and bovine gamma-globulin or bovine serum albumin as carriers. In contrast to mammalian systems, the secondary anti-hapten response in the sea robin was found to involve exclusively high molecular weight antibody.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Absorption
  • Animals
  • Antibodies / analysis
  • Antibody Formation*
  • Cattle / immunology
  • Centrifugation, Density Gradient
  • Coliphages / immunology
  • Dinitrophenols / immunology*
  • Fishes / immunology*
  • Haptens
  • Immune Sera / analysis
  • Immunization
  • Immunoelectrophoresis
  • Neutralization Tests
  • Serum Albumin, Bovine / immunology*
  • gamma-Globulins / immunology*

Substances

  • Antibodies
  • Dinitrophenols
  • Haptens
  • Immune Sera
  • gamma-Globulins
  • Serum Albumin, Bovine