Abstract
Hepatic function failed to influence serum concentrations of the antifungal agent 5-fluorocytosine when the drug was given intravenously to rabbits with CCl(4)-induced hepatic insufficiency or orally to a patient with postnecrotic cirrhosis.
MeSH terms
-
Animals
-
Antifungal Agents / blood*
-
Carbon Tetrachloride Poisoning / blood
-
Chemical and Drug Induced Liver Injury / blood
-
Cytosine / blood*
-
Flucytosine / blood
-
Humans
-
Liver Cirrhosis / blood
-
Liver Diseases / blood*
-
Rabbits
-
Time Factors
Substances
-
Antifungal Agents
-
Cytosine
-
Flucytosine