Myofibroblasts and free silicon around breast implants

Plast Reconstr Surg. 1978 Aug;62(2):185-96. doi: 10.1097/00006534-197808000-00006.

Abstract

Fibrous tissue capsules, from around silicone breast implants, were examined by light microscopy, and by transmission and scanning electron microscopy, the latter combined with energy dispersive X-ray analysis. Contractile fibroblasts (myofibroblasts) were found in most of these fibrous capsules, and especially in those recently formed or manipulated. The element silicon was positively identified by X-ray analysis in half the tissue specimens. This material was found only around gel-filled implants. In the specimens studied, the clinical hardness of the breast was unrelated to the presence of silicon in the capsule.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Breast / pathology
  • Breast / surgery*
  • Female
  • Fibroblasts / ultrastructure
  • Humans
  • Postoperative Complications / pathology*
  • Postoperative Complications / prevention & control
  • Prostheses and Implants*
  • Silicon / analysis
  • Silicones
  • Surgery, Plastic*
  • Triamcinolone / administration & dosage

Substances

  • Silicones
  • Triamcinolone
  • Silicon