Comparison between two non-halogenated glucocorticoid ointments in psoriasis

J Int Med Res. 1981;9(4):239-47. doi: 10.1177/030006058100900401.

Abstract

Observations made in a controlled double-blind investigation of two non-halogenated topical steroids, hydrocortisone-17-butyrate (HCB) and budesonide in thirty-six patients with psoriasis revealed a clear difference in therapeutic effect between the two ointments, indicating that they belong to different groups of topical steroids according to a classification accepted in the Nordic countries. Budesonide had a good therapeutic effect in all the patients studied, while, as a rule, HCB was clearly less effective.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Administration, Topical
  • Anti-Inflammatory Agents / therapeutic use*
  • Budesonide
  • Clinical Trials as Topic
  • Dermatologic Agents / administration & dosage*
  • Double-Blind Method
  • Female
  • Glucocorticoids / administration & dosage*
  • Humans
  • Hydrocortisone / administration & dosage
  • Hydrocortisone / analogs & derivatives*
  • Male
  • Middle Aged
  • Ointments
  • Pregnenediones / administration & dosage*
  • Psoriasis / drug therapy

Substances

  • Anti-Inflammatory Agents
  • Dermatologic Agents
  • Glucocorticoids
  • Ointments
  • Pregnenediones
  • hydrocortisone-17-butyrate
  • Budesonide
  • Hydrocortisone