Design of a benchtop alpha particle irradiator

Health Phys. 1995 May;68(5):710-5. doi: 10.1097/00004032-199505000-00012.

Abstract

The design, construction and calibration of a convenient irradiator is described that provides controlled exposure to a uniform external source of well-characterized alpha particles at a dose-rate of 0.99 cGy min-1. The use of a precis- ion photographic shutter allows the accurate delivery of doses as low as 0.01 mGy (1 mrad) to cultured cells. Special features also include a helium environment and reciprocal collimator that permits the use of collimators with different transmission factors to achieve differing dose-rates. A simple method is described to characterize the energy spectrum of alpha particles by use of particle range as measured by track etch.

MeSH terms

  • Alpha Particles* / adverse effects
  • Biophysical Phenomena
  • Biophysics
  • Cells, Cultured
  • Environmental Exposure
  • Humans
  • Linear Energy Transfer
  • Radiation Dosage
  • Radiometry / instrumentation
  • Technology, Radiologic / instrumentation*