Abstract
The MeOH extract of the stem of Dendrobium loddigesii was found to inhibit the aggregation of rabbit platelets induced by arachidonic acid and collagen. Two active compounds, moscatilin [1] and moscatin [2], were isolated. Moscatilin diacetate [3] also exhibited antiplatelet aggregation activity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Arachidonic Acid / antagonists & inhibitors
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Arachidonic Acid / pharmacology
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Benzyl Compounds / isolation & purification*
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Benzyl Compounds / pharmacology
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Collagen / antagonists & inhibitors
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Collagen / pharmacology
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Drugs, Chinese Herbal / pharmacology*
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In Vitro Techniques
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Phenanthrenes / isolation & purification*
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Phenanthrenes / pharmacology
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Platelet Aggregation Inhibitors / isolation & purification*
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Platelet Aggregation Inhibitors / pharmacology
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Rabbits
Substances
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Benzyl Compounds
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Drugs, Chinese Herbal
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Phenanthrenes
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Platelet Aggregation Inhibitors
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moscatin
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dendrophenol
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Arachidonic Acid
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Collagen