Gadolinium-enhanced MR aortography

Radiology. 1994 Apr;191(1):155-64. doi: 10.1148/radiology.191.1.8134563.

Abstract

Purpose: To evaluate the potential for preferential arterial enhancement at magnetic resonance (MR) aortography with an intravenous infusion of paramagnetic contrast material.

Materials and methods: Gadolinium chelates were administered intravenously (0.2 mmol/kg) during three-dimensional MR imaging (1.5 T) in 125 patients (77 male and 48 female patients, aged 4-86 years [mean, 66 years]) with suspected aorta or aortic branch vessel disease.

Results: Infusion for the duration of the MR acquisition resulted in significant preferential arterial enhancement without the confounding effects of excessive venous or background-tissue enhancement (P < 10(-5)). Angiographic or surgical correlation in 48 patients revealed an 88% sensitivity and a 97% specificity for detection of stenoses or occlusions and a 100% sensitivity and a 100% specificity for detection of aortic or iliac artery aneurysms.

Conclusion: Preferential arterial enhancement is possible at MR aortography with an intravenous infusion of paramagnetic contrast material.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Aorta / pathology*
  • Aortic Aneurysm / diagnosis
  • Child
  • Child, Preschool
  • Contrast Media*
  • Drug Combinations
  • Female
  • Gadolinium DTPA
  • Gadolinium*
  • Heterocyclic Compounds
  • Humans
  • Iliac Aneurysm / diagnosis
  • Magnetic Resonance Imaging*
  • Male
  • Meglumine
  • Middle Aged
  • Organometallic Compounds
  • Pentetic Acid / analogs & derivatives
  • Sensitivity and Specificity
  • Vena Cava, Inferior / pathology

Substances

  • Contrast Media
  • Drug Combinations
  • Heterocyclic Compounds
  • Organometallic Compounds
  • gadoteridol
  • Meglumine
  • Pentetic Acid
  • gadodiamide
  • Gadolinium
  • Gadolinium DTPA