(2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol: a novel antidepressant agent and selective inhibitor of norepinephrine uptake

J Med Chem. 1996 Jan 19;39(2):347-9. doi: 10.1021/jm950630p.

Authors

J L Kelley¹, D L Musso, G E Boswell, F E Soroko, B R Cooper

Affiliation

¹ Division of Organic Chemistry, Burroughs Wellcome Co., Research Triangle Park, North Carolina 27709, USA.

PMID: 8558500
DOI: 10.1021/jm950630p

No abstract available

MeSH terms

Animals
Antidepressive Agents / chemistry
Antidepressive Agents / pharmacology*
Behavior, Animal / drug effects
Dose-Response Relationship, Drug
Mice
Morpholines / chemistry
Morpholines / pharmacology*
Norepinephrine / antagonists & inhibitors*
Norepinephrine / metabolism*
Rats

Substances

2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol
Antidepressive Agents
Morpholines
Norepinephrine