Toxoplasma IgG. & IgM. antibodies. A case control study

J Egypt Soc Parasitol. 1995 Dec;25(3):877-82.

Abstract

This study includes 62 cases of spontaneous abortions and 75 cross matched non pregnant multiparous women as controls. Micro-ELISA test was done to measure Toxoplasma IgM & IgG antibodies. Out of 62 aborting women, 26 gave positive anti-Toxoplasma IgG antibodies, more than 45 Eu/ml and 28 gave positive anti-Toxoplasma IgM antibodies, more than 40 Eu/ml without statistical significant difference. There was a significant difference between aborting women and the controls as regards IgG & IgM antibodies. IgG antibodies, showed statistical significant difference between those with no history of abortions or I-2 abortions versus those with 3 or more abortions. The infection was more among aborting women in rural than urban areas whom suffered poor hygienic measures and awareness about the mode of transmission of Toxoplasma infection. The results were discussed.

Publication types

  • Comparative Study

MeSH terms

  • Abortion, Spontaneous / blood
  • Abortion, Spontaneous / immunology*
  • Animals
  • Antibodies, Protozoan / blood*
  • Case-Control Studies
  • Congenital Abnormalities
  • Enzyme-Linked Immunosorbent Assay / methods
  • Female
  • Fetal Death
  • Humans
  • Immunoglobulin G / blood*
  • Immunoglobulin M / blood*
  • Infant, Newborn
  • Pregnancy / blood
  • Pregnancy / immunology*
  • Reference Values
  • Rural Population
  • Socioeconomic Factors
  • Toxoplasma / immunology*
  • Urban Population

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G
  • Immunoglobulin M