Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure

Antimicrob Agents Chemother. 1995 Dec;39(12):2593-601. doi: 10.1128/AAC.39.12.2593.

Author

J R Knox¹

Affiliation

¹ Department of Molecular and Cell Biology, University of Connecticut, Storrs 06269-3125, USA. knox@uconnvm.uconn.edu

No abstract available

Publication types

Review

MeSH terms

Amino Acid Sequence
Animals
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / metabolism
Anti-Bacterial Agents / pharmacology
Bacteria / drug effects
Bacteria / enzymology*
Bacteria / genetics*
Binding Sites
Crystallography, X-Ray
Humans
Molecular Sequence Data
Mutation
Protein Conformation
Substrate Specificity
beta-Lactam Resistance / genetics*
beta-Lactamase Inhibitors
beta-Lactamases / chemistry*
beta-Lactamases / genetics
beta-Lactamases / metabolism
beta-Lactams

Substances

Anti-Bacterial Agents
beta-Lactamase Inhibitors
beta-Lactams
beta-Lactamases