Makaluvamines H-M and damirone C from the pohnpeian sponge Zyzzya fuliginosa

E W Schmidt; M K Harper; D J Faulkner

doi:10.1021/np50126a008

Makaluvamines H-M and damirone C from the pohnpeian sponge Zyzzya fuliginosa

J Nat Prod. 1995 Dec;58(12):1861-7. doi: 10.1021/np50126a008.

Authors

E W Schmidt¹, M K Harper, D J Faulkner

Affiliation

¹ Scripps Institution of Oceanography, University of California at San Diego, La Jolla 92093-0212, USA.

PMID: 8691207
DOI: 10.1021/np50126a008

Abstract

Seven new pyrroloiminoquinone alkaloids, makaluvamines H-M [19-24] and damirone C[25], together with the known compounds, makaluvamines C[13], D[14], and G[17], were isolated from the sponge Zyzzya fuliginosa collected at Nahpali Island, Pohnpei, Micronesia. The structures of the new compounds were elucidated by interpretation of spectral data. The chemotaxonomic relationships involving the makaluvamines and related pyrroloiminoquinone alkaloids are discussed.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Animals
Anti-Infective Agents / isolation & purification*
Anti-Infective Agents / pharmacology
Imidazoles / isolation & purification*
Imidazoles / pharmacology
Magnetic Resonance Spectroscopy
Porifera / chemistry*
Quinolines / isolation & purification*
Quinolines / pharmacology
Spectrophotometry, Infrared

Substances

Anti-Infective Agents
Imidazoles
Quinolines
damirone C

Grants and funding

CA 49084/CA/NCI NIH HHS/United States