Abstract
Antiviral activity-guided isolation studies on the leaves of Atalantia monophylla (ROXB.) CORR. (Rutaceae) led to the identification of pyropheophorbide a (1), a simple chlorin derivative, from the chloroform extract (fr. B) as a possible antiviral active principle against herpes simplex virus type 2 (HSV-2). Pyropheophorbide a methyl ester (2) was also isolated from the hexane extract (fr. A).
MeSH terms
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Animals
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Antiviral Agents / isolation & purification*
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Antiviral Agents / pharmacology*
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Chlorocebus aethiops
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Chlorophyll / analogs & derivatives*
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Chlorophyll / isolation & purification
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Chlorophyll / pharmacology
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Herpesvirus 2, Human / drug effects*
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Herpesvirus 2, Human / growth & development
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Plant Extracts / pharmacology
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Vero Cells
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Viral Plaque Assay
Substances
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Antiviral Agents
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Plant Extracts
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Chlorophyll
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pyropheophorbide a