Abstract
We have used a new technique of bleomycin injection to treat intractable palmar, plantar and periungual warts. Following local anaesthesia with topical EMLA (lignocaine and prilocaine) cream, 1 mg/ml bleomycin solution was dropped on to the wart and 'pricked' into the wart using a Monolet needle. We achieved 92% success rate which compares well with other authors whose success rates with intralesional bleomycin vary between 33 and 92%. We conclude that this technique of intralesional bleomycin therapy is an effective, safe and generally well tolerated treatment for recalcitrant warts.
MeSH terms
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Adolescent
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Adult
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Aged
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Antimetabolites, Antineoplastic / administration & dosage*
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Antimetabolites, Antineoplastic / adverse effects
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Antimetabolites, Antineoplastic / therapeutic use
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Bleomycin / administration & dosage*
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Bleomycin / adverse effects
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Bleomycin / therapeutic use
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Female
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Foot Dermatoses / drug therapy*
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Foot Dermatoses / pathology
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Hand Dermatoses / drug therapy*
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Hand Dermatoses / pathology
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Humans
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Injections, Intralesional
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Male
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Middle Aged
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Raynaud Disease / chemically induced
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Warts / drug therapy*
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Warts / pathology
Substances
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Antimetabolites, Antineoplastic
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Bleomycin