Abstract
Heterologous mycobactins and the synthetic FR160 [N4-nonyl,N1,N8-bis(2,3-dihydroxybenzoyl) spermidine hydrobromide (C3 0H4 6N3, O6 Br)] promoted growth in Mycobacterium aurum in low concentrations. They were otherwise highly inhibitory, as opposed to homologous mycobactin, which was strictly growth promoting. Desferrioxamine B (Desferal) had no significant effect on growth.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Division / drug effects
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Deferoxamine / pharmacology*
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Evaluation Studies as Topic
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Mycobacterium / drug effects*
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Oxazoles / pharmacology*
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Siderophores / pharmacology*
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Spermidine / analogs & derivatives*
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Spermidine / pharmacology
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Time Factors
Substances
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FR 160
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Oxazoles
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Siderophores
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mycobactins
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Deferoxamine
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Spermidine