Black women are less likely to be diagnosed with breast cancer than white women but more likely to be adversely affected. However, little attention has been paid to how these women cope with the disease. Using a comparative design, this study analyzes the differences in religiousness between black and white women with breast cancer. Findings suggest that black women rely on religiousness as a coping resource to a greater extent than white women. Implications for how this information can be used in social work practice with black women are discussed.