Isotemporal Substitution as the Gold Standard Model for Physical Activity Epidemiology: Why It Is the Most Appropriate for Activity Time Research

Int J Environ Res Public Health. 2019 Mar 5;16(5):797. doi: 10.3390/ijerph16050797.

Rania A Mekary^{1

2

3}, Eric L Ding⁴

¹ Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. RMekary@hsph.harvard.edu.
² Department of Pharmaceutical Business and Administrative Sciences, School of Pharmacy, MCPHS University, 179 Longwood Avenue, Boston, MA 02115, USA. RMekary@hsph.harvard.edu.
³ Department of Neurosurgery, Computational Neuroscience Outcomes Center, Brigham and Women's Hospital, Harvard Medical School, 15 Francis Street, Boston, MA 02115, USA. RMekary@hsph.harvard.edu.
⁴ Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. eding@post.harvard.edu.

Abstract

Isotemporal substitution model was first developed in 2009 [...].