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    Blcap bladder cancer associated protein [ Mus musculus (house mouse) ]

    Gene ID: 53619, updated on 30-Apr-2024

    Summary

    Official Symbol
    Blcapprovided by MGI
    Official Full Name
    bladder cancer associated proteinprovided by MGI
    Primary source
    MGI:MGI:1858907
    See related
    Ensembl:ENSMUSG00000067787 AllianceGenome:MGI:1858907
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bc10
    Summary
    Predicted to be involved in apoptotic nuclear changes. Predicted to act upstream of or within apoptotic process. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain and spinal cord. Orthologous to human BLCAP (BLCAP apoptosis inducing factor). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 60.0), CNS E18 (RPKM 57.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    2 H1; 2 78.4 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (157398282..157408281, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (157556362..157566361, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene Rous sarcoma oncogene Neighboring gene VISTA enhancer mm1673 Neighboring gene predicted gene 14279 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:157392020-157392207 Neighboring gene neuronatin Neighboring gene STARR-seq mESC enhancer starr_06215 Neighboring gene pluripotency associated transcript 27 Neighboring gene STARR-seq mESC enhancer starr_06217 Neighboring gene predicted gene, 34293

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • MGC102074

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in apoptotic nuclear changes ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    bladder cancer-associated protein
    Names
    Blcapbladder cancer associated protein homolog
    bladder cancer 10 kDa protein
    bladder cancer associated protein homolog
    bladder cancer related protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355426.1NP_001342355.1  bladder cancer-associated protein

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      AL672259
      Consensus CDS
      CCDS16979.1
      UniProtKB/Swiss-Prot
      A2AFZ4, P62951, Q3TD76, Q5XJG3
      Related
      ENSMUSP00000085849.3, ENSMUST00000088494.3
      Conserved Domains (1) summary
      pfam06726
      Location:165
      BC10; Bladder cancer-related protein BC10
    2. NM_016916.3NP_058612.3  bladder cancer-associated protein

      See identical proteins and their annotated locations for NP_058612.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein.
      Source sequence(s)
      BC083339, BM950751, BY718283
      Consensus CDS
      CCDS16979.1
      UniProtKB/Swiss-Prot
      A2AFZ4, P62951, Q3TD76, Q5XJG3
      Related
      ENSMUSP00000105154.3, ENSMUST00000109528.9
      Conserved Domains (1) summary
      pfam06726
      Location:165
      BC10; Bladder cancer-related protein BC10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      157398282..157408281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)