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    mkg-p monkey king protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38955, updated on 10-May-2024

    Summary

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    Official Symbol
    mkg-pprovided by FlyBase
    Official Full Name
    monkey king proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0035889
    Locus tag
    Dmel_CG7163
    See related
    AllianceGenome:FB:FBgn0035889
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG7163; Dmel\CG7163; MK; mkg; mkg-r; mkgr; MKI; TUTase6
    Summary
    Predicted to enable RNA uridylyltransferase activity. Predicted to be involved in mRNA polyadenylation. Predicted to be active in cytosol. Is expressed in organism. Human ortholog(s) of this gene implicated in liver benign neoplasm. Orthologous to human TUT4 (terminal uridylyl transferase 4). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    See mkg-p in Genome Data Viewer
    Location:
    66C11-66C11; 3-24 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (8402168..8405277, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (8395268..8398377, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Jonah 66Ci Neighboring gene Jonah 66Cii Neighboring gene uncharacterized protein Neighboring gene tRNA 2'-phosphotransferase Neighboring gene uncharacterized protein Neighboring gene Outer segment 1 Neighboring gene Exocyst 70 Neighboring gene matrimony

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Duplication-degeneration as a mechanism of gene fission and the origin of new genes in Drosophila species. Wang W, et al. Nat Genet, 2004 May. PMID 15064762
    2. Evolution of miRNA Tailing by 3' Terminal Uridylyl Transferases in Metazoa. Modepalli V, et al. Genome Biol Evol, 2017 Jun 1. PMID 28633361, Free PMC Article
    3. A deficiency screen of the major autosomes identifies a gene (matrimony) that is haplo-insufficient for achiasmate segregation in Drosophila oocytes. Harris D, et al. Genetics, 2003 Oct. PMID 14573476, Free PMC Article
    4. Repetitive element-mediated recombination as a mechanism for new gene origination in Drosophila. Yang S, et al. PLoS Genet, 2008 Jan. PMID 18208328, Free PMC Article
    5. A gain-of-function screen identifying genes required for vein formation in the Drosophila melanogaster wing. Molnar C, et al. Genetics, 2006 Nov. PMID 16980395, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables RNA uridylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA uridylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA 3' uridylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    monkey king protein
    Names
    3' terminal uridylyl transferase 6
    CG7163-PA
    CG7163-PB
    CG7163-PD
    mkg-p-PA
    mkg-p-PB
    mkg-p-PD
    monkey king
    monkey-king
    NP_001286981.1
    NP_648219.1
    NP_729375.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      8402168..8405277 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168272.2 → NP_729375.1  monkey king protein, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729375.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6Q376, Q95U58
      Related
      FBpp0076387
      Conserved Domains (1) summary
      cd05402
      Location:104 → 216
      NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases

    2. NM_001300052.1 → NP_001286981.1  monkey king protein, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286981.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6Q376, Q95U58
      Conserved Domains (1) summary
      cd05402
      Location:104 → 216
      NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases

    3. NM_139962.4 → NP_648219.1  monkey king protein, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_648219.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q6Q376, Q95U58
      Related
      FBpp0076388
      Conserved Domains (1) summary
      cd05402
      Location:104 → 216
      NT_PAP_TUTase; Nucleotidyltransferase (NT) domain of poly(A) polymerases and terminal uridylyl transferases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6Q376 Q6Q376
    Q95U58 Q95U58

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