This CCDS ID represents the longer mouse Hck isoform, known as p59Hck, as described in PMID:1875927. This isoform initiates translation from a non-AUG (CUG) start codon that is well-conserved and present in a strong Kozak signal context. Alternative translation initiation from a downstream AUG start codon produces an isoform that is 21 aa shorter at the N-terminus. The shorter isoform, which is known as p56Hck, is represented by CCDS 50756.1. These isoforms exhibit distinct subcellular localization, as indicated in PMID:1875927.
Red highlighting indicates amino acids encoded across a splice junction.
Mouse over the nucleotide or protein sequence below and click on the highlighted codon or residue to select the pair. This works on the replacement symbol in the Translation Exceptions section also.
Translation Exceptions: replace the symbol L (codon CTG) with M at amino acid position 1