Arabidopsis thaliana gene ATTAP1, encoding ATTAP1 (Arabidopsis thaliana transporter associated with antigen processing protein 1); ATPase, coupled to transmembrane movement of substances.
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SUMMARY back to top
TAIR annotates one representative transcript.

AceView synopsis, each blue text links to tables and details
According to AceView, this gene is well expressed, 0.8 times the average gene in this release. The sequence of this gene is defined by 31 GenBank accessions from 29 cDNA clones, some from mixture of silique and flower (seen 5 times), see description (5), aerial (4), flower, leaf and root (2), ovule (once), whole plant (once).
The gene contains 17 distinct introns (16 gt-ag, 1 gc-ag). Transcription produces one mRNA.
Efficacy of translation may be reduced by the presence of a shorter translated product (uORF) initiating at an AUG upstream of the main open reading frame (in variant aOct08).
Function: There is one article specifically referring to this gene in PubMed. Functionally, the gene has been proposed to participate in a process (transport). Proteins are expected to have molecular functions (transporter activity, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances) and to localize in various compartments (membrane, integral to membrane).
Please see the Arabidopsis TAIR site TAIR:AT1G70610 for in depth functional annotation of this gene.
The spliced mRNA putatively encodes a good protein, containing domains ABC transporter, transmembrane region, ABC transporter-like [Pfam], some transmembrane domains [Psort2].

Please quote: AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12.
Map on chromosome 1, links to other databases and other names
Map: This gene ATTAP1 maps on chromosome 1. In AceView, it covers 4.55 kb, from 26625624 to 26630172 (NCBI 7_1, April 2007), on the direct strand.
Links to: manual annotations from TAIR:AT1G70610, the SNP view, gene overviews from Entrez Gene 843398, expression data from UniGene.
Other names: The gene is also known as ATTAP1, At1g70610, Arabidopsis thaliana transporter associated with antigen processing protein 1, F5A18.21 or F5A18_21, LOC843398. It has been described as ATTAP1 (Arabidopsis thaliana transporter associated with antigen processing protein 1); ATPase, coupled to transmembrane movement of substances.
Closest AceView homologs in other species ?
The closest human gene, according to BlastP, is the AceView gene ABCB9 (e= 10-107).
The closest mouse genes, according to BlastP, are the AceView genes Abcb9 (e= 10-106), Abcb10 (e=4 10-94).
The closest C.elegans genes, according to BlastP, are the AceView/WormGenes haf-2 (e= 10-111), haf-9 (e= 10-104), haf-4 (e= 10-102), which may contain interesting functional annotation
          Complete gene on genome diagram: back to top
Please choose between the zoomable GIF version., and the HTML5/SVG version.
This diagram shows in true scale the gene on the genome, the mRNAs and the cDNA clones.
Compact gene diagram back to top
Gene ATTAP1 5' 3' encoded on plus strand of chromosome 1 from 26,625,624 to 26,630,172 a [NM] 5kb 0 575 bp exon 575 bp exon 39 bp uORF 575 bp exon 575 bp exon 123 bp [gt-ag] intron 10 GenBank accessions 128 bp exon 128 bp exon 154 bp [gt-ag] intron 8 GenBank accessions 43 bp exon 43 bp exon 89 bp [gt-ag] intron 8 GenBank accessions 45 bp exon 45 bp exon 98 bp [gt-ag] intron 7 GenBank accessions 123 bp exon 123 bp exon 90 bp [gt-ag] intron 4 GenBank accessions 104 bp exon 104 bp exon 116 bp [gt-ag] intron 3 GenBank accessions 55 bp exon 55 bp exon 82 bp [gt-ag] intron 3 GenBank accessions 71 bp exon 71 bp exon 153 bp [gt-ag] intron 5 GenBank accessions 103 bp exon 103 bp exon 144 bp [gt-ag] intron 4 GenBank accessions 211 bp exon 211 bp exon 232 bp [gc-ag] intron 4 GenBank accessions 74 bp exon 74 bp exon 383 bp [gt-ag] intron 4 GenBank accessions 57 bp exon 57 bp exon 88 bp [gt-ag] intron 4 GenBank accessions 75 bp exon 75 bp exon 79 bp [gt-ag] intron 4 GenBank accessions 75 bp exon 75 bp exon 84 bp [gt-ag] intron 4 GenBank accessions 282 bp exon 282 bp exon 69 bp [gt-ag] intron 16 GenBank accessions 65 bp exon 65 bp exon 74 bp [gt-ag] intron 15 GenBank accessions 61 bp exon 61 bp exon 85 bp [gt-ag] intron 15 GenBank accessions 254 bp exon 254 bp exon 29 accessions, NM_105729 some from mixture of silique and flower (seen 5 times) see description (5), aerial (4) flower, leaf and root (2) ovule (once) Validated 3' end, 1 accession 254 bp exon Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
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Sequences: click on the numbers to get the DNA back to top
mRNA variant mRNA matching the genome Best predicted protein 5' UTR 3' UTR uORF Upstream sequence Transcription
unit
pre-mRNA
Downstream sequence
aOct08 2401 bp 700 aa 125 bp 173 bp 36 bp 2kb probably including promoter 4544 bp 1kb

Gene neighbors and Navigator on chromosome 1 back to top
AT1G70430 C AT1G70450 C AT1G70460 C R P AT1G70480 C R AT1G70505 C R KNAT2 D C P EDA24 C P AT1G70550 C R AT1G70560 C P AT1G70570 C AOAT2 C R P AT1G70581 C P AT1G70590 C ATTAP1 C R P AT1G70620 C R AT1G70630 C R AT1G70640 C AT1G70650 C R MMZ2/UEV1B C P AT1G70670 C R AT1G70680 C AT1G70690 C P JAZ9/TIFY7 C R P AT1G70720 C AT1G70760 C R AT1G70790 C R AT1G70800 C AT1G70810 C P AT1G70820 C MIR777a C C C R C R P AT1G70410 C AT1G70420 C SRO3 C AT1G70470 C R P ATARFA1D C AT1G70500 C C AT1G70520 C AT1G70530 C P C P AT1G70600 C P AtGH9B1 C AT1G70730 C R AT1G70740 C R AT1G70750 R R C R P AT1G70770 C AT1G70780 C R P MLP28 C MLP31 C R MLP34 10 20kb 0 AT1G70430, 1 accession AT1G70450, 1 accession AT1G70460, 3 accessions AT1G70480, 57 accessions 2 variants AT1G70505, 2 accessions 2 variants KNAT2, 7 accessions EDA24, 10 accessions AT1G70550, 20 accessions 2 variants AT1G70560, 18 accessions AT1G70570, 29 accessions 2 variants AOAT2, 62 accessions, 4 variants AT1G70581, 42 accessions AT1G70590, 17 accessions ATTAP1, 29 accessions AT1G70620, 43 accessions 4 variants AT1G70630, 5 accessions AT1G70640, 4 accessions AT1G70650, 5 accessions MMZ2/UEV1B, 47 accessions AT1G70670, 28 accessions AT1G70680, 14 accessions AT1G70690, 32 accessions JAZ9/TIFY7, 136 accessions 4 variants AT1G70720, 25 accessions AT1G70760, 135 accessions AT1G70790, 32 accessions 3 variants AT1G70800, 4 accessions AT1G70810, 38 accessions AT1G70820, 30 accessions keydaw, 1 accession kleefee, 1 accession klerfee, 4 accessions kordaw, 1 accession klorfee, 1 accession kloyfee, 4 accessions ladaw, 2 accessions ludaw, 1 accession MIR777a, 1 accession plyfee, 1 accession kleyfee, 1 accession koydaw, 1 accession plafee, 2 accessions lydaw, 1 accession lodaw, 2 accessions leedaw, 1 accession AT1G70380, 1 accession AT1G70390, 1 accession AT1G70400, 70 accessions 3 variants AT1G70410, 214 accessions 3 variants AT1G70420, 12 accessions SRO3, 6 accessions AT1G70470, 11 accessions ATARFA1D, 231 accessions 3 variants AT1G70500, 16 accessions jodu, 1 accession AT1G70520, 27 accessions AT1G70530, 11 accessions lardaw, 24 accessions AT1G70600, 428 accessions AtGH9B1, 155 accessions AT1G70730, 51 accessions AT1G70740, 17 accessions 2 variants AT1G70750, 5 accessions plufee, 2 accessions plofee, 2 accessions AT1G70770, 141 accessions 2 variants AT1G70780, 237 accessions 2 variants MLP28, 258 accessions 5 variants MLP31, 7 accessions MLP34, 214 accessions 3 variants ZOOM IN                D:disease,C:conserved,I:interactions,R:regulation,P:publications         Read more...
Annotated mRNA diagrams back to top
Bibliography:               1 article in PubMed back to top
? Gene Summary Gene on genome mRNA Expression Tissue Function, regulation, related genes C

To mine knowledge about the gene, please click the 'Gene Summary' or the 'Function, regulation, related genes ' tab at the top of the page. The 'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The 'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To see the mRNA diagram, sequence and annotation, click the 'mRNA' tab. To examine expression data from all cDNAs clustered in this gene by AceView, click the 'Expression tissue'.

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