RefSeq summary
[ABCC4] The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions. Alternative splicing results in multiple splice variants encoding different isoforms. [provided by RefSeq].
RefSeq annotates 2 representative transcripts (NM included in AceView variants .a and .c), but Homo sapiens cDNA sequences in GenBank, dbEST, Trace and SRA, filtered against clone rearrangements, coaligned on the genome and clustered in a minimal non-redundant way by the manually supervised AceView program, support at least 18 spliced variants .
AceView synopsis, each blue text links to tables and details
Note that this locus is complex: it appears to produce several proteins with no sequence overlap.
Expression: According to AceView, this gene is
expressed at very high level , 5.2 times the average gene in this release. The
sequence of this gene is defined by
575 GenBank accessions from 553 cDNA clones, some from prostate (seen 319 times), stomach (37), kidney (22), lung (18), prostate normal (12), brain (10), 2 pooled tumors (clear cell type) (6) and 76 other
tissues . We annotate
structural defects or features in 46 cDNA clones.
Alternative mRNA variants and regulation: The gene contains
46 distinct gt-ag introns . Transcription produces
21 different mRNAs , 18 alternatively spliced variants and 3 unspliced forms. There are 10 probable
alternative promotors , 5 non overlapping alternative last exons and 5 validated
alternative polyadenylation sites (see the
diagram ). The mRNAs appear to differ by truncation of the 5' end, truncation of the 3' end, presence or absence of 7
cassette exons , overlapping exons with different boundaries. 206 bp of this gene
are antisense to spliced gene plerdoby , raising the possibility of regulated alternate expression.
Note that mRNA .hAug10 was found
in vivo , although it is a predicted target of
nonsense mediated mRNA decay (NMD).
Efficacy of translation may be reduced by the presence of a shorter translated product (
uORF ) initiating at an AUG upstream of the main open reading frame (in variant iAug10).
Function: There are
69 articles specifically referring to this gene in PubMed. Functionally, the gene has been tested for association to
diseases (Carcinoma, Small Cell; Neuroblastoma), proposed to participate in
pathway (ABC transporters) and
processes (ion transport, transmembrane transport). Proteins are expected to have molecular
functions (15-hydroxyprostaglandin dehydrogenase (NAD+) activity, ATP binding, ATPase activity, ATPase activity, coupled to transmembrane movement of substances, chloride channel activity, nucleotide binding) and to
localize in various compartments (membrane fraction, plasma membrane, platelet dense granule membrane, integral to membrane).
Protein coding potential: 15 spliced and the unspliced mRNAs putatively encode
good proteins , altogether
15 different isoforms (7 complete, 3 COOH complete, 5 partial ), some containing
domains ABC transporter transmembrane region, ABC transporter [Pfam], some transmembrane domains
[Psort2] . The remaining 5 mRNA variants (3 spliced, 2 unspliced; 2 partial) appear not to encode good proteins. Finally proteins from this gene may be modulated by
acetylation; phosphorylation; ubiquitination , as detailed at PhosphoSite.
Please quote:
AceView: a comprehensive cDNA-supported gene and transcripts annotation, Genome Biology 2006, 7(Suppl 1):S12 .
Map on chromosome 13, links to other databases and other names
Map: This gene ABCC4 maps on chromosome 13, at 13q32 according to Entrez Gene. In AceView, it covers
281.62 kb , from 95953700 to 95672081 (NCBI 37, August 2010), on the reverse strand.
Links to: manual annotations from
KEGG_02010 ,
PhosphoSite , the
SNP view, gene overviews from
Entrez Gene 10257 ,
GeneCards , expression data from
ECgene ,
UniGene , molecular and other annotations from
UCSC , or our
GOLD analysis.
The previous AceView annotation is
here .
Other names: The gene is also known as ABCC4, RP11-74A12.1, MRP4, MOATB, MOAT-B or EST170205, LOC10257. It has been described as multidrug resistance-associated protein 4, MRP/cMOAT-related ABC transporter, multispecific organic anion transporter B, ATP-binding cassette sub-family C member 4, multi-specific organic anion transporter B, bA464I2.1 (ATP-binding cassette, sub-family C (CFTR/MRP), member 4), canalicular multispecific organic anion transporter (ABC superfamily).
Closest AceView homologs in other species
?
The closest mouse gene , according to BlastP, is the AceView gene
Abcc4 (e=10
-05 ).
The closest C.elegans genes , according to BlastP, are the AceView/WormGenes
mrp-2 (e=2 10
-96 ),
mrp-1 (e=5 10
-96 ),
mrp-4 (e=10
-93 ),
mrp-6 (e=2 10
-92 ),
mrp-7 (e=2 10
-88 ),
mrp-8 (e=7 10
-88 ),
mrp-3 (e=2 10
-86 ), which may contain interesting functional annotation.
The closest A.thaliana genes , according to BlastP, are the AceView genes
ATMRP5 (e= 10
-105 ),
ATMRP2 (e= 10
-103 ),
ATMRP1 (e= 10
-101 ),
ATMRP12 (e=2 10
-99 ),
ATMRP13 (e=8 10
-98 ),
ATMRP10 (e=6 10
-97 ),
ATMRP4 (e=3 10
-96 ),
ATMRP14 (e=2 10
-91 ), which may contain interesting functional annotation
ABCC4
Gene expression in 15 primates, 16 tissues, from the NHPRTR project in sFPKM
BAB
SkeletalMuscle
WholeBlood
CHP
Kidney
Liver
Lung
Spleen
CMC
CMM
Cerebellum
HUM
Brain
Colon
Heart
LymphNode
Ovary
Testis
JMI
BoneMarrow
MLM
OWL
PTM
RMC
RMI
Pituitary
SQM
Thymus
MST
SMY
RTL
4.71
3.33
11.6
1.26
9.41
5.04
5.40
3.33
7.64
0.68
5.40
5.40
18.8
4.71
30.6
0.96
8.78
8.78
9.41
16.4
16.4
8.19
7.13
13.3
0.72
1.55
37.6
16.4
3.57
5.79
4.39
7.64
14.3
1.26
12.4
7.64
11.6
3.82
3.82
20.2
0.72
2.70
11.6
3.57
61.1
4.39
3.10
7.64
5.40
0.27
2.35
0.63
6.65
46.3
10.1
6.65
8.19
7.64
7.13
3.33
1.66
3.10
4.10
6.21
7.13
11.6
2.35
16.4
0.48
26.6
53.2
1.26
2.70
3.10
7.13
4.10
10.1
7.64
2.90
18.8
86.5
7.64
2.19
9.41
13.3
7.13
12.4
3.33
7.13
3.33
11.6
14.3
2.52
131
5.79
26.6
5.40
5.04
10.8
4.71
0.68
8.78
40.3
2.90
12.4
10.1
14.3
4.10
10.1
9.41
6.21
24.8
106
5.04
11.6
4.39
4.71
9.41
9.41
13.3
1.02
5.04
3.33
2.70
4.39
35.1
6.21
20.2
13.3
35.1
3.57
9.41
10.8
8.19
14.3
20.2
15.3
15.3
13.3
5.79
3.33
3.33
92.7
5.79
28.5
5.40
14.3
4.71
15.3
11.6
1.35
1.45
4.39
12.4
7.64
16.4
7.13
Expression
quantiles
None
Weak
1
2
3
4
5
6
7
8
10
20
This gene
All genes
log2 distributions
RNA-seq gene expression profile across 16 selected tissues from the Non-Human Primates Reference Transcriptome Resource (link to
NHPRTR project ).
- Primates:
Apes (
HUM : Human (Illumina BodyMap 2),
CHP : Chimpanzee),
Old World monkeys (
PTM : Pig-Tailed Macaque,
JMI Japanese Macaque,
RMI Rhesus Macaque Indian,
RMC Rhesus Macaque Chinese,
CMM Cynomolgus Macaque Mauritian,
CMC Cynomolgus Macaque Chinese,
BAB Olive Baboon,
SMY Sooty Mangabey);
New World monkeys (
MST common Marmoset,
SQM Squirrel Monkey,
OWL Owl Monkey); and
Lemurs (
MLM Mouse Lemur,
RTL Ring-Tailed Lemur).
- The level for significantly expressed genes is color coded in 8 equal sized bins (light to dark green). Light gray is for weak not-accurately measured expression (2 to 8 reads above intergenic background); dark gray for no expression or no sequence conservation (0 read in gene). The plot to the right shows the distribution of measured expression values in all tissues for
all genes (blue) and for
this gene (green) , in Magic index = log
2 (1000 sFPKM).
You may also examine the strand-specific
genome coverage plots on the experimental AceView/Magic hub at UCSC , by tissue or by species. Tracks may be
slow to load ; please reload if some tracks come up yellow-greenish, and thanks to UCSC for the great work!.
Read more...
About UCSC tracks: you may enjoy the plots for the summed coverage over all primates' libraries (top track), summarizing 3 terabases of stranded RNA-seq. Fragments mapping on the + strand of the genome (from genes on the + strand) are red (or dark), on minus strand blue (or light) and antisense transcribed areas are black or overlaid. The vertical scale for each track is self-adapting. Homozygous SNPs tracks are also presented.
About mapping: Primates body map RNA-seq data were stringently mapped to the human genome using the NCBI Magic pipeline. Normalized results are shown as significant FPKM (sFPKM), which includes corrections on F, K and M, computed from parameters measured directly in each RNA-seq experiment, to render the expression measures more significant and more robust to experimental biases. Only fragments with both reads mapped uniquely and over at least 80+80 bases ending with 8 exact bases on each side of each read, and facing each other in a single site or gene, are included in the computation of the sFPKM/index, in the coverage plots, and in the determination of homozygous SNPs (minimum coverage 10, minimum allele frequency 95%). But be aware that genes whose sequence evolved to become too distant from Human cannot be measured well, this bias can be appreciated in the per-species coverage plots at UCSC.
About libraries: For non-human primates, total RNA libraries used TruSeq, ribozero and the stranded UDG protocol. The human 2010 libraries used the polyA selected non-stranded protocol, with short reads (50, 75 or 50+50 bases); furthermore the insert lengths are larger in human than in the non-human primates (average insert size 187 bp in non-human primates versus 232 bp in human). These protocol differences may impact expression measures for the non polyadenylated genes (or genes with shorter or occasional polyA tails), for the pseudogenes or close gene families (specificity is reduced in humans due to shorter reads), and for the very short genes.
Complete gene on genome diagram:
Compact gene diagram
Gene ABCC4
5'
3'
encoded on minus strand of chromosome 13 from 95,953,700 to 95,672,081
3838
10023
7400
10730
9493
9690
11610
11639
a
[NM]
3838
93
10023
7400
10730
9493
9690
11610
11639
b
3838
10023
c
[NM]
s
1
11639
i
3838
18
10023
d
11610
61
m
381
136
e
q-u
1
11639
l
381
495
f
10730
n
p
383
g
j-u
202
304
r
3838
217
h
16
7400
10730
9493
9690
t
13
11639
k
u-u
9493
o
10kb
0
206 bp exon
206 bp exon
53487 bp [gt-ag] intron
22 GenBank accessions
3816 RNA-seq supporting reads
1326 UHR pooled cells
150 Brain
688 Blood
1640 Neuroblastoma
12 Other
(also 2901 Primates bodymap)
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
210 bp exon
1639 bp [gt-ag] intron
21 GenBank accessions
18953 RNA-seq supporting reads
3878 UHR pooled cells
372 Brain
11186 Blood
3470 Neuroblastoma
47 Other
(also 3373 Primates bodymap)
141 bp exon
730 bp [gt-ag] intron
21 GenBank accessions
15983 RNA-seq supporting reads
3793 UHR pooled cells
390 Brain
8470 Blood
3274 Neuroblastoma
56 Other
(also 4181 Primates bodymap)
38 bp exon
393 bp [gt-ag] intron
21 GenBank accessions
13896 RNA-seq supporting reads
3978 UHR pooled cells
406 Brain
5908 Blood
3550 Neuroblastoma
54 Other
(also 4602 Primates bodymap)
95 bp exon
1786 bp [gt-ag] intron
23 GenBank accessions
15214 RNA-seq supporting reads
4207 UHR pooled cells
395 Brain
6854 Blood
3699 Neuroblastoma
59 Other
(also 5359 Primates bodymap)
147 bp exon
45187 bp [gt-ag] intron
20 GenBank accessions
10003 RNA-seq supporting reads
3801 UHR pooled cells
353 Brain
2494 Blood
3314 Neuroblastoma
41 Other
(also 4286 Primates bodymap)
80 bp exon
32631 bp [gt-ag] intron
11 GenBank accessions
7389 RNA-seq supporting reads
2784 UHR pooled cells
263 Brain
1578 Blood
2724 Neuroblastoma
40 Other
(also 3065 Primates bodymap)
151 bp exon
7588 bp [gt-ag] intron
12 GenBank accessions
10718 RNA-seq supporting reads
4170 UHR pooled cells
413 Brain
2000 Blood
4090 Neuroblastoma
45 Other
(also 4190 Primates bodymap)
120 bp exon
1107 bp [gt-ag] intron
10 GenBank accessions
9483 RNA-seq supporting reads
3551 UHR pooled cells
297 Brain
1919 Blood
3675 Neuroblastoma
41 Other
(also 3346 Primates bodymap)
111 bp exon
909 bp [gt-ag] intron
10 GenBank accessions
9680 RNA-seq supporting reads
3873 UHR pooled cells
344 Brain
1480 Blood
3942 Neuroblastoma
41 Other
(also 3819 Primates bodymap)
101 bp exon
1350 bp [gt-ag] intron
17 GenBank accessions
9202 RNA-seq supporting reads
3504 UHR pooled cells
338 Brain
1630 Blood
3703 Neuroblastoma
27 Other
(also 3990 Primates bodymap)
192 bp exon
8802 bp [gt-ag] intron
12 GenBank accessions
10754 RNA-seq supporting reads
4174 UHR pooled cells
388 Brain
1750 Blood
4392 Neuroblastoma
50 Other
(also 4239 Primates bodymap)
156 bp exon
9519 bp [gt-ag] intron
19 GenBank accessions
11591 RNA-seq supporting reads
5047 UHR pooled cells
400 Brain
1207 Blood
4871 Neuroblastoma
66 Other
(also 4536 Primates bodymap)
90 bp exon
8656 bp [gt-ag] intron
19 GenBank accessions
10791 RNA-seq supporting reads
4251 UHR pooled cells
362 Brain
1930 Blood
4206 Neuroblastoma
42 Other
(also 4948 Primates bodymap)
173 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
106 bp exon
8942 bp [gt-ag] intron
52 GenBank accessions
11587 RNA-seq supporting reads
4503 UHR pooled cells
473 Brain
1595 Blood
4984 Neuroblastoma
32 Other
(also 4329 Primates bodymap)
135 bp exon
12922 bp [gt-ag] intron
30 GenBank accessions
9284 RNA-seq supporting reads
3559 UHR pooled cells
341 Brain
1454 Blood
3888 Neuroblastoma
42 Other
(also 3319 Primates bodymap)
1854 bp exon
359 accessions, NM_005845.3
some from prostate (seen 292 times)
lung (8), brain (5), head neck (3)
bladder (2)
capped 5' end, 6 accessions
1854 bp exon
79 bp exon
79 bp exon
53487 bp [gt-ag] intron
22 GenBank accessions
3816 RNA-seq supporting reads
1326 UHR pooled cells
150 Brain
688 Blood
1640 Neuroblastoma
12 Other
(also 2901 Primates bodymap)
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
210 bp exon
2510 bp [gt-ag] intron
1 GenBank accession
92 RNA-seq supporting reads
30 UHR pooled cells
2 Brain
27 Blood
33 Neuroblastoma
(also 3 Primates bodymap)
38 bp exon
393 bp [gt-ag] intron
21 GenBank accessions
13896 RNA-seq supporting reads
3978 UHR pooled cells
406 Brain
5908 Blood
3550 Neuroblastoma
54 Other
(also 4602 Primates bodymap)
95 bp exon
1786 bp [gt-ag] intron
23 GenBank accessions
15214 RNA-seq supporting reads
4207 UHR pooled cells
395 Brain
6854 Blood
3699 Neuroblastoma
59 Other
(also 5359 Primates bodymap)
147 bp exon
45187 bp [gt-ag] intron
20 GenBank accessions
10003 RNA-seq supporting reads
3801 UHR pooled cells
353 Brain
2494 Blood
3314 Neuroblastoma
41 Other
(also 4286 Primates bodymap)
80 bp exon
32631 bp [gt-ag] intron
11 GenBank accessions
7389 RNA-seq supporting reads
2784 UHR pooled cells
263 Brain
1578 Blood
2724 Neuroblastoma
40 Other
(also 3065 Primates bodymap)
151 bp exon
7588 bp [gt-ag] intron
12 GenBank accessions
10718 RNA-seq supporting reads
4170 UHR pooled cells
413 Brain
2000 Blood
4090 Neuroblastoma
45 Other
(also 4190 Primates bodymap)
120 bp exon
1107 bp [gt-ag] intron
10 GenBank accessions
9483 RNA-seq supporting reads
3551 UHR pooled cells
297 Brain
1919 Blood
3675 Neuroblastoma
41 Other
(also 3346 Primates bodymap)
111 bp exon
909 bp [gt-ag] intron
10 GenBank accessions
9680 RNA-seq supporting reads
3873 UHR pooled cells
344 Brain
1480 Blood
3942 Neuroblastoma
41 Other
(also 3819 Primates bodymap)
101 bp exon
1350 bp [gt-ag] intron
17 GenBank accessions
9202 RNA-seq supporting reads
3504 UHR pooled cells
338 Brain
1630 Blood
3703 Neuroblastoma
27 Other
(also 3990 Primates bodymap)
192 bp exon
8802 bp [gt-ag] intron
12 GenBank accessions
10754 RNA-seq supporting reads
4174 UHR pooled cells
388 Brain
1750 Blood
4392 Neuroblastoma
50 Other
(also 4239 Primates bodymap)
156 bp exon
9519 bp [gt-ag] intron
19 GenBank accessions
11591 RNA-seq supporting reads
5047 UHR pooled cells
400 Brain
1207 Blood
4871 Neuroblastoma
66 Other
(also 4536 Primates bodymap)
90 bp exon
8656 bp [gt-ag] intron
19 GenBank accessions
10791 RNA-seq supporting reads
4251 UHR pooled cells
362 Brain
1930 Blood
4206 Neuroblastoma
42 Other
(also 4948 Primates bodymap)
173 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
106 bp exon
8942 bp [gt-ag] intron
52 GenBank accessions
11587 RNA-seq supporting reads
4503 UHR pooled cells
473 Brain
1595 Blood
4984 Neuroblastoma
32 Other
(also 4329 Primates bodymap)
135 bp exon
12922 bp [gt-ag] intron
30 GenBank accessions
9284 RNA-seq supporting reads
3559 UHR pooled cells
341 Brain
1454 Blood
3888 Neuroblastoma
42 Other
(also 3319 Primates bodymap)
129 bp exon
1 accession from kidney
129 bp exon
206 bp exon
206 bp exon
53487 bp [gt-ag] intron
22 GenBank accessions
3816 RNA-seq supporting reads
1326 UHR pooled cells
150 Brain
688 Blood
1640 Neuroblastoma
12 Other
(also 2901 Primates bodymap)
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
210 bp exon
1639 bp [gt-ag] intron
21 GenBank accessions
18953 RNA-seq supporting reads
3878 UHR pooled cells
372 Brain
11186 Blood
3470 Neuroblastoma
47 Other
(also 3373 Primates bodymap)
141 bp exon
730 bp [gt-ag] intron
21 GenBank accessions
15983 RNA-seq supporting reads
3793 UHR pooled cells
390 Brain
8470 Blood
3274 Neuroblastoma
56 Other
(also 4181 Primates bodymap)
38 bp exon
393 bp [gt-ag] intron
21 GenBank accessions
13896 RNA-seq supporting reads
3978 UHR pooled cells
406 Brain
5908 Blood
3550 Neuroblastoma
54 Other
(also 4602 Primates bodymap)
95 bp exon
1786 bp [gt-ag] intron
23 GenBank accessions
15214 RNA-seq supporting reads
4207 UHR pooled cells
395 Brain
6854 Blood
3699 Neuroblastoma
59 Other
(also 5359 Primates bodymap)
147 bp exon
45187 bp [gt-ag] intron
20 GenBank accessions
10003 RNA-seq supporting reads
3801 UHR pooled cells
353 Brain
2494 Blood
3314 Neuroblastoma
41 Other
(also 4286 Primates bodymap)
80 bp exon
19742 bp [gt-ag] intron
9 GenBank accessions
1100 RNA-seq supporting reads
625 UHR pooled cells
49 Brain
221 Blood
204 Neuroblastoma
1 Other
409 bp exon
4 accessions, NM_001105515.1
some from brain (seen once)
brain, neuroblastoma (once)
tongue, tumor tissue (once)
Validated 3' end, 2 accessions
Validated 3' end, 1 accession
409 bp exon
573 bp exon
573 bp exon
1350 bp [gt-ag] intron
17 GenBank accessions
9202 RNA-seq supporting reads
3504 UHR pooled cells
338 Brain
1630 Blood
3703 Neuroblastoma
27 Other
(also 3990 Primates bodymap)
12 accessions, some from prostate normal (seen 12 times)
129 bp exon
235 bp exon
235 bp exon
180 bp uORF
235 bp exon
513 bp [gt-ag] intron
1 GenBank accession
180 bp uORF
90 bp exon
90 bp exon
8656 bp [gt-ag] intron
19 GenBank accessions
10791 RNA-seq supporting reads
4251 UHR pooled cells
362 Brain
1930 Blood
4206 Neuroblastoma
42 Other
(also 4948 Primates bodymap)
173 bp exon
173 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
106 bp exon
106 bp exon
8942 bp [gt-ag] intron
52 GenBank accessions
11587 RNA-seq supporting reads
4503 UHR pooled cells
473 Brain
1595 Blood
4984 Neuroblastoma
32 Other
(also 4329 Primates bodymap)
135 bp exon
135 bp exon
12922 bp [gt-ag] intron
30 GenBank accessions
9284 RNA-seq supporting reads
3559 UHR pooled cells
341 Brain
1454 Blood
3888 Neuroblastoma
42 Other
(also 3319 Primates bodymap)
1854 bp exon
1854 bp exon
157 accessions, some from stomach (seen 35 times)
prostate (26), kidney (18)
lung (10), 2 pooled tumors (clear cell type) (6)
capped 5' end, 2 accessions
Validated 3' end, 1 accession
Validated 3' end, 21 accessions
1854 bp exon
192 bp exon
192 bp exon
53487 bp [gt-ag] intron
22 GenBank accessions
3816 RNA-seq supporting reads
1326 UHR pooled cells
150 Brain
688 Blood
1640 Neuroblastoma
12 Other
(also 2901 Primates bodymap)
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
36193 bp [gt-ag] intron
2 GenBank accessions
16 RNA-seq supporting reads
8 UHR pooled cells
4 Blood
4 Neuroblastoma
(also 34 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
210 bp exon
1639 bp [gt-ag] intron
21 GenBank accessions
18953 RNA-seq supporting reads
3878 UHR pooled cells
372 Brain
11186 Blood
3470 Neuroblastoma
47 Other
(also 3373 Primates bodymap)
141 bp exon
730 bp [gt-ag] intron
21 GenBank accessions
15983 RNA-seq supporting reads
3793 UHR pooled cells
390 Brain
8470 Blood
3274 Neuroblastoma
56 Other
(also 4181 Primates bodymap)
38 bp exon
393 bp [gt-ag] intron
21 GenBank accessions
13896 RNA-seq supporting reads
3978 UHR pooled cells
406 Brain
5908 Blood
3550 Neuroblastoma
54 Other
(also 4602 Primates bodymap)
95 bp exon
1786 bp [gt-ag] intron
23 GenBank accessions
15214 RNA-seq supporting reads
4207 UHR pooled cells
395 Brain
6854 Blood
3699 Neuroblastoma
59 Other
(also 5359 Primates bodymap)
147 bp exon
45187 bp [gt-ag] intron
20 GenBank accessions
10003 RNA-seq supporting reads
3801 UHR pooled cells
353 Brain
2494 Blood
3314 Neuroblastoma
41 Other
(also 4286 Primates bodymap)
80 bp exon
19742 bp [gt-ag] intron
9 GenBank accessions
1100 RNA-seq supporting reads
625 UHR pooled cells
49 Brain
221 Blood
204 Neuroblastoma
1 Other
411 bp exon
8 accessions, some from poorly differentiated adenocarcinoma withsignet ring cell features (seen 2 times)
stomach (2), thalamus (2)
Validated 3' end, 2 accessions
411 bp exon
151 bp exon
151 bp exon
9519 bp [gt-ag] intron
19 GenBank accessions
11591 RNA-seq supporting reads
5047 UHR pooled cells
400 Brain
1207 Blood
4871 Neuroblastoma
66 Other
(also 4536 Primates bodymap)
90 bp exon
18355 bp [gt-ag] intron
2 GenBank accessions
59 RNA-seq supporting reads
21 UHR pooled cells
3 Blood
35 Neuroblastoma
(also 4 Primates bodymap)
135 bp exon
12922 bp [gt-ag] intron
30 GenBank accessions
9284 RNA-seq supporting reads
3559 UHR pooled cells
341 Brain
1454 Blood
3888 Neuroblastoma
42 Other
(also 3319 Primates bodymap)
535 bp exon
2 accessions
capped 5' end, 1 accession
535 bp exon
95 bp exon
95 bp exon
31818 bp [gt-ag] intron
2 GenBank accessions
379 RNA-seq supporting reads
78 UHR pooled cells
10 Brain
194 Blood
97 Neuroblastoma
113 bp exon
21556 bp [gt-ag] intron
1 GenBank accession
135 RNA-seq supporting reads
24 UHR pooled cells
3 Brain
50 Blood
58 Neuroblastoma
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
145 bp exon
1 accession
145 bp exon
898 bp exon
898 bp exon
2 accessions, some from liver and spleen (seen once)
898 bp exon
14 bp exon
2897 bp [gt-ag] intron
1 GenBank accession
90 bp exon
90 bp exon
8656 bp [gt-ag] intron
19 GenBank accessions
10791 RNA-seq supporting reads
4251 UHR pooled cells
362 Brain
1930 Blood
4206 Neuroblastoma
42 Other
(also 4948 Primates bodymap)
173 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
106 bp exon
8942 bp [gt-ag] intron
52 GenBank accessions
11587 RNA-seq supporting reads
4503 UHR pooled cells
473 Brain
1595 Blood
4984 Neuroblastoma
32 Other
(also 4329 Primates bodymap)
82 bp exon
1 accession
capped 5' end, 1 accession
82 bp exon
95 bp exon
31818 bp [gt-ag] intron
2 GenBank accessions
379 RNA-seq supporting reads
78 UHR pooled cells
10 Brain
194 Blood
97 Neuroblastoma
113 bp exon
3045 bp [gt-ag] intron
1 GenBank accession
494 RNA-seq supporting reads
93 UHR pooled cells
4 Brain
308 Blood
87 Neuroblastoma
2 Other
153 bp exon
18358 bp [gt-ag] intron
3 GenBank accessions
1686 RNA-seq supporting reads
391 UHR pooled cells
24 Brain
899 Blood
368 Neuroblastoma
4 Other
(also 144 Primates bodymap)
111 bp exon
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
145 bp exon
1 accession
145 bp exon
151 bp exon
7588 bp [gt-ag] intron
12 GenBank accessions
10718 RNA-seq supporting reads
4170 UHR pooled cells
413 Brain
2000 Blood
4090 Neuroblastoma
45 Other
(also 4190 Primates bodymap)
548 bp exon
2 accessions, some from ovary (seen 2 times)
tumor, 5 pooled (see description) (2)
548 bp exon
64 bp exon
64 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
468 bp exon
1 accession from human skeletal muscle
468 bp exon
95 bp exon
34976 bp [gt-ag] intron
2 GenBank accessions
381 RNA-seq supporting reads
146 UHR pooled cells
9 Brain
91 Blood
134 Neuroblastoma
1 Other
(also 99 Primates bodymap)
153 bp exon
18358 bp [gt-ag] intron
3 GenBank accessions
1686 RNA-seq supporting reads
391 UHR pooled cells
24 Brain
899 Blood
368 Neuroblastoma
4 Other
(also 144 Primates bodymap)
111 bp exon
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
203 bp [gt-ag] intron
22 GenBank accessions
11122 RNA-seq supporting reads
2916 UHR pooled cells
283 Brain
5151 Blood
2713 Neuroblastoma
59 Other
(also 6157 Primates bodymap)
87 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
97 bp exon
4164 bp [gt-ag] intron
23 GenBank accessions
15248 RNA-seq supporting reads
3726 UHR pooled cells
373 Brain
7893 Blood
3207 Neuroblastoma
49 Other
(also 5884 Primates bodymap)
145 bp exon
2 accessions, some from kidney (seen once)
145 bp exon
1196 bp exon
1196 bp exon
27 bp uORF
1196 bp exon
1196 bp exon
4 accessions, some from liver and spleen (seen 4 times)
1196 bp exon
58 bp exon
4945 bp [gt-ag] intron
1 GenBank accession
201 RNA-seq supporting reads
61 UHR pooled cells
8 Brain
49 Blood
83 Neuroblastoma
(also 5 Primates bodymap)
107 bp exon
3890 bp [gt-ag] intron
1 GenBank accession
303 RNA-seq supporting reads
104 UHR pooled cells
13 Brain
88 Blood
98 Neuroblastoma
(also 7 Primates bodymap)
135 bp exon
135 bp exon
12922 bp [gt-ag] intron
30 GenBank accessions
9284 RNA-seq supporting reads
3559 UHR pooled cells
341 Brain
1454 Blood
3888 Neuroblastoma
42 Other
(also 3319 Primates bodymap)
486 bp exon
2 accessions, some from prostate (seen once)
486 bp exon
170 bp exon
170 bp exon
53487 bp [gt-ag] intron
22 GenBank accessions
3816 RNA-seq supporting reads
1326 UHR pooled cells
150 Brain
688 Blood
1640 Neuroblastoma
12 Other
(also 2901 Primates bodymap)
111 bp exon
547 bp [gt-ag] intron
26 GenBank accessions
7177 RNA-seq supporting reads
1712 UHR pooled cells
159 Brain
3392 Blood
1890 Neuroblastoma
24 Other
(also 5080 Primates bodymap)
121 bp exon
12140 bp [gt-ag] intron
25 GenBank accessions
6369 RNA-seq supporting reads
1461 UHR pooled cells
146 Brain
3211 Blood
1523 Neuroblastoma
28 Other
(also 3095 Primates bodymap)
225 bp exon
23828 bp [gt-ag] intron
19 GenBank accessions
6433 RNA-seq supporting reads
1945 UHR pooled cells
208 Brain
2147 Blood
2121 Neuroblastoma
12 Other
(also 3001 Primates bodymap)
90 bp exon
1094 bp [gt-ag] intron
23 GenBank accessions
6780 RNA-seq supporting reads
1860 UHR pooled cells
175 Brain
2805 Blood
1919 Neuroblastoma
21 Other
(also 2744 Primates bodymap)
164 bp exon
1508 bp [gt-ag] intron
22 GenBank accessions
8456 RNA-seq supporting reads
2674 UHR pooled cells
236 Brain
2896 Blood
2623 Neuroblastoma
27 Other
(also 6756 Primates bodymap)
126 bp exon
1018 bp [gt-ag] intron
19 GenBank accessions
8724 RNA-seq supporting reads
2404 UHR pooled cells
245 Brain
3818 Blood
2224 Neuroblastoma
33 Other
(also 4270 Primates bodymap)
250 bp exon
11594 bp [gt-ag] intron
19 GenBank accessions
7869 RNA-seq supporting reads
2530 UHR pooled cells
246 Brain
2632 Blood
2433 Neuroblastoma
28 Other
(also 4619 Primates bodymap)
102 bp exon
6293 bp [gt-ag] intron
19 GenBank accessions
7603 RNA-seq supporting reads
2669 UHR pooled cells
233 Brain
2010 Blood
2664 Neuroblastoma
27 Other
(also 4089 Primates bodymap)
90 bp exon
1560 bp [gt-ag] intron
20 GenBank accessions
8284 RNA-seq supporting reads
2440 UHR pooled cells
227 Brain
3206 Blood
2385 Neuroblastoma
26 Other
(also 3727 Primates bodymap)
192 bp exon
8609 bp [gt-ag] intron
22 GenBank accessions
14025 RNA-seq supporting reads
3942 UHR pooled cells
366 Brain
6024 Blood
3639 Neuroblastoma
54 Other
(also 7303 Primates bodymap)
95 bp exon
208 bp [gt-ag] intron
1 GenBank accession
216 RNA-seq supporting reads
70 UHR pooled cells
3 Brain
62 Blood
77 Neuroblastoma
4 Other
(also 22 Primates bodymap)
82 bp exon
82 bp exon
7078 bp [gt-ag] intron
25 GenBank accessions
10016 RNA-seq supporting reads
2830 UHR pooled cells
251 Brain
4102 Blood
2806 Neuroblastoma
27 Other
(also 3359 Primates bodymap)
1 accession
407 bp exon
64 bp exon
32894 bp [gt-ag] intron
1 GenBank accession
15 RNA-seq supporting reads
15 UHR pooled cells
80 bp exon
32631 bp [gt-ag] intron
11 GenBank accessions
7389 RNA-seq supporting reads
2784 UHR pooled cells
263 Brain
1578 Blood
2724 Neuroblastoma
40 Other
(also 3065 Primates bodymap)
151 bp exon
7588 bp [gt-ag] intron
12 GenBank accessions
10718 RNA-seq supporting reads
4170 UHR pooled cells
413 Brain
2000 Blood
4090 Neuroblastoma
45 Other
(also 4190 Primates bodymap)
120 bp exon
1107 bp [gt-ag] intron
10 GenBank accessions
9483 RNA-seq supporting reads
3551 UHR pooled cells
297 Brain
1919 Blood
3675 Neuroblastoma
41 Other
(also 3346 Primates bodymap)
111 bp exon
111 bp exon
909 bp [gt-ag] intron
10 GenBank accessions
9680 RNA-seq supporting reads
3873 UHR pooled cells
344 Brain
1480 Blood
3942 Neuroblastoma
41 Other
(also 3819 Primates bodymap)
1 accession from tongue
tumor tissue
capped 5' end, 1 accession
35 bp exon
250 bp exon
250 bp exon
2385 bp [gt-ag] intron
1 GenBank accession
12 RNA-seq supporting reads
4 UHR pooled cells
2 Blood
6 Neuroblastoma
(also 4 Primates bodymap)
90 bp exon
8656 bp [gt-ag] intron
19 GenBank accessions
10791 RNA-seq supporting reads
4251 UHR pooled cells
362 Brain
1930 Blood
4206 Neuroblastoma
42 Other
(also 4948 Primates bodymap)
173 bp exon
478 bp [gt-ag] intron
183 GenBank accessions
9715 RNA-seq supporting reads
3701 UHR pooled cells
373 Brain
1724 Blood
3873 Neuroblastoma
44 Other
(also 4183 Primates bodymap)
106 bp exon
8942 bp [gt-ag] intron
52 GenBank accessions
11587 RNA-seq supporting reads
4503 UHR pooled cells
473 Brain
1595 Blood
4984 Neuroblastoma
32 Other
(also 4329 Primates bodymap)
1 accession
capped 5' end, 1 accession
15 bp exon
369 bp exon
369 bp exon
1 accession from ovary
369 bp exon
279 bp exon
279 bp exon
1107 bp [gt-ag] intron
10 GenBank accessions
9483 RNA-seq supporting reads
3551 UHR pooled cells
297 Brain
1919 Blood
3675 Neuroblastoma
41 Other
(also 3346 Primates bodymap)
78 bp exon
1 accession from prostate tumor
78 bp exon
Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, intron height reflects the number of cDNAs supporting each intron, the small numbers show the support of the introns in deep sequencing (with details in mouse-over) . Introns of the same color are identical, of different colors are different. 'Good proteins' are pink, partial or not-good proteins are yellow, uORFs are green. 5' cap or3' poly A flags show completeness of the transcript.
Read more...
Mouse over the ending of each transcript gives tissues from which the supporting cDNAs were extracted. Details on tissue of origin for each intron and exon is available from the
intron and exons table .
Click on any transcript to open the specific mRNA page, to see the exact cDNA clone support and eventual SNPs and to get details on tissues, sequences, mRNA and protein annotations. Proteins supported by a single continuous cDNA sequence lead to underlining the name/ending of the variant. Names not underlined result from cDNA concatenation in the coding region and should be experimentally checked.
Introns are depicted by broken lines; the height of the top of each intron reflects the relative number of clones supporting this intron.
]^[ A pink broken line denotes an intron with standard boundaries (gt-ag or gc-ag) that is exactly supported (i.e. a cDNA sequence exactly matches the genome over 16 bp, 8 on both sides of the intron).
] ^ ] A blue broken line denotes non-standard introns, exactly supported, but with non-standard at-ac or any other boundaries.
]-[ Pink and
] - ] blue straight lines represent 'fuzzy' introns of the standard and non-standard types respectively, those introns do not follow the 16 bp rule. Black straight lines ]-[denote gaps in the alignments.
Exons: Wide filled pink areas represent putative protein coding regions, narrow empty pink boxes represent the 5'UTR (on the left) and 3' UTR (on the right). Flags identify validated endings: cap site on the 5' side, polyadenylation site on the 3' side. Filled flags correspond to frequent events while empty flags have lesser supporting cDNAs (yet all are validated); at the 3' side, black flags are associated to the main AATAAA signal,
blue flags to any single letter variant of the main . More explanations are given in the
gene help file
Sequences: click on the numbers to get the DNA
Gene neighbors and Navigator on chromosome 13q32
D
C
R
P
ABCC4
10
20kb
0
pleedarby, 1 accession
neypy, 1 accession
skershobu, 3 accessions
ratyby, 1 accession
ploydarby, 1 accession
slashobu, 1 accession
torzaw, 1 accession
skudarby, 1 accession
skawdarby, 1 accession
skeedarby, 1 accession
skerdarby, 1 accession
zotyby, 1 accession
slodarby, 1 accession
zeetyby, 1 accession
slawshobu, 1 accession
chotyby, 1 accession
shoytyby, 1 accession
sleedarby, 1 accession
sleydarby, 1 accession
sloydarby, 1 accession
sweynor, 3 accessions
plawdarby, 4 accessions
gerchaw, 3 accessions
pleydarby, 1 accession
skadarby, 2 accessions
skydarby, 1 accession
tazaw, 1 accession
wartyby, 1 accession
soytabo, 1 accession
vyzoy, 2 accessions
skardarby, 1 accession
woytyby, 1 accession
skordarby, 1 accession
skoydarby, 1 accession
sludarby, 1 accession
zozaw, 1 accession
zarzaw, 1 accession
slardarby, 1 accession
pleedoby, 3 accessions
sleeshobu, 1 accession
sleyshobu, 2 accessions
slordarby, 1 accession
smadarby, 1 accession
slorshobu, 1 accession
zeyzaw, 1 accession
ABCC4, 565 accessions
21 variants
ZOOM OUT
D :disease,
C :conserved,
I :interactions,
R :regulation,
P :publications
Read more...
R
R
R
CLDN10
D
C
R
P
P
R
P
SOX21
D
C
R
P
ABCC4
R
R
C
I
R
P
DZIP1
100kb
0
kumuri, 21 accessions
swonor, 3 accessions, 2 variants
plerdoby, 13 accessions
3 variants
CLDN10, 134 accessions
6 variants
deetyby, 1 accession
klodarby, 1 accession
klawdarby, 1 accession
kleedarby, 1 accession
skoshobu, 1 accession
skarshobu, 1 accession
vazoy, 3 accessions
fartyby, 2 accessions
lytyby, 1 accession
mawtyby, 2 accessions
pladarby, 2 accessions
pludarby, 1 accession
patyby, 1 accession
pleedarby, 1 accession
neypy, 1 accession
skershobu, 3 accessions
ratyby, 1 accession
ploydarby, 1 accession
slashobu, 1 accession
torzaw, 1 accession
skudarby, 1 accession
skawdarby, 1 accession
skeedarby, 1 accession
skerdarby, 1 accession
zotyby, 1 accession
slodarby, 1 accession
zeetyby, 1 accession
slawshobu, 1 accession
chotyby, 1 accession
shoytyby, 1 accession
sleedarby, 1 accession
sleydarby, 1 accession
sloydarby, 1 accession
sweynor, 3 accessions
smardarby, 1 accession
smeydarby, 1 accession
smoydarby, 4 accessions
snodarby, 1 accession
snardarby, 2 accessions
smushobu, 1 accession
smoshobu, 1 accession
smarshobu, 1 accession
snerdarby, 1 accession
tutabo, 1 accession
plordoy, 2 accessions
smorshobu, 1 accession
spudarby, 2 accessions
jysner, 1 accession
plawtyby, 1 accession
smoyshobu, 1 accession
speedarby, 1 accession
snyshobu, 1 accession
shyzaw, 1 accession
sperdarby, 1 accession
shuzaw, 1 accession
vawzoy, 1 accession
spoydarby, 1 accession
stadarby, 1 accession
ployshobu, 1 accession
skashobu, 4 accessions
2 variants
herere, 1 accession
stornor, 13 accessions
2 variants
klerdarby, 1 accession
raware, 1 accession
sazaw, 1 accession
kleydarby, 1 accession
doytyby, 1 accession
klordarby, 1 accession
skawshobu, 1 accession
plydarby, 1 accession
plodarby, 1 accession
plardarby, 3 accessions
seyzaw, 1 accession
plawdarby, 4 accessions
gerchaw, 3 accessions
pleydarby, 1 accession
skadarby, 2 accessions
skydarby, 1 accession
tazaw, 1 accession
wartyby, 1 accession
soytabo, 1 accession
vyzoy, 2 accessions
skardarby, 1 accession
woytyby, 1 accession
skordarby, 1 accession
skoydarby, 1 accession
sludarby, 1 accession
zozaw, 1 accession
zarzaw, 1 accession
slardarby, 1 accession
pleedoby, 3 accessions
sleeshobu, 1 accession
sleyshobu, 2 accessions
slordarby, 1 accession
smadarby, 1 accession
slorshobu, 1 accession
zeyzaw, 1 accession
glotyby, 1 accession
smodarby, 3 accessions
smawdarby, 1 accession
smeedarby, 1 accession
smerdarby, 1 accession
borsner, 5 accessions
snadarby, 2 accessions
snydarby, 1 accession
snudarby, 1 accession
chawzaw, 1 accession
smyshobu, 2 accessions
hamumi, 1 accession
swoynor, 1 accession
smershobu, 1 accession
waseri, 2 accessions
smeyshobu, 1 accession
snoydarby, 1 accession
snashobu, 1 accession
norere, 1 accession
turere, 3 accessions
spordarby, 1 accession
sleetyby, 1 accession
skydoy, 2 accessions
stydarby, 1 accession
snushobu, 1 accession
blarzaw, 1 accession
morere, 1 accession
SOX21, 39 accessions, 2 variants
ABCC4, 565 accessions
21 variants
snawdarby, 2 accessions
zywobo, 3 accessions
DZIP1, 211 accessions
18 variants
ZOOM IN
D :disease,
C :conserved,
I :interactions,
R :regulation,
P :publications
Read more...
Annotated mRNA diagrams
The mRNAs diagrams with the aligned cDNA sequence accessions and their mismatches are available in the mRNA pages accessible from the tab at the top of the page, or here:
In Flash:
.a , .i , .c , .b , .d , .h , .m , .g , .f , .e , .o , .s , .u-u , .j-u , .t , .p , .r , .q-u , .n , .l , .k .
or in GIF:
.a , .i , .c , .b , .d , .h , .m , .g , .f , .e , .o , .s , .u-u , .j-u , .t , .p , .r , .q-u , .n , .l , .k
Bibliography:   69 articles in PubMed
? Gene Summary
Gene on genome
mRNA: .a , .b , .c , .d , .e , .f , .g , .h , .i , .j-u , .k , .l , .m , .n , .o , .p , .q-u , .r , .s , .t , .u-u
Alternative mRNAs features, proteins, introns, exons, sequences
Expression Tissue
Function, regulation, related genes D C
To
mine knowledge about the gene, please click the
'Gene Summary' or the
'Function, regulation, related genes ' tab at the top of the page. The
'Gene Summary' page includes all we learnt about the gene, functional annotations of neighboring genes, maps, links to other sites and the bibliography. The
'Function, regulation, related genes ' page includes Diseases (D), Pathways, GO annotations, conserved domains (C), interactions (I) reference into function, and pointers to all genes with the same functional annotation.
To
compare alternative variants , their summarized annotations, predicted proteins, introns and exons, or to access any sequence, click the
'Alternative mRNAs features' tab. To see a
specific mRNA variant diagram, sequence and annotation, click the variant name in the
'mRNA' tab. To examine
expression data from all cDNAs clustered in this gene by AceView, click the
'Expression tissue' .
If you know more about this gene, or found errors, please
share your knowledge. Thank you !