5O91_A 30 YSILKQIGSGGSSKVFQVLN-EKKQIYAIKYVNLEEADNQTL------DSYRNEIAYLNKLQqhSDKIIRLYDYEIT--- 99 human P32490 221 IETLGILGEGAGGSVSKCKLkNGSKIFALKVINTLNTDPEYQ------KQIFRELQFNRSFQ--SEYIVRYYGMFTDd-e 291 Saccharomyces cerevi... P06784 191 LVQLGKIGAGNSGTVVKALHvPDSKIVAKKTIPVEQNNSTII------NQLVRELSIVKNVKp-HENIITFYGAYYNqhi 263 Saccharomyces cerevi... P10506 66 LEVVRHLGEGNGGAVSLVK--HRNIFMARKTVYVGSDSKLQ-------KQILRELGVLHHCR--SPYIVGFYGAFQY--- 131 Schizosaccharomyces ... 4UY9_A 11 LTLEEIIGIGGFGKVYRAF--WIGDEVAVKAARHDPDEDISQt----iENVRQEAKLFAMLK--HPNIIALRGVCLK--- 79 human P17801 534 RKFKVELGRGESGTVYKGVl-EDDRHVAVKKLENVRQGK---------EVFQAELSVIGRIN--HMNLVRIWGFCSE--- 598 Zea mays Q03497 620 YANLVKIGQGASGGVYTAYEiGTNVSVAIKQMNLEKQPKKEL--------IINEILVMKGSK--HPNIVNFIDSYVL--- 686 Saccharomyces cerevi... P27636 25 YHLKQVIGRGSYGVVYKAINkHTDQVVAIKEVVYENDEELND--------IMAEISLLKNLN--HNNIVKYHGFIRK--- 91 Saccharomyces cerevi... P28829 394 WIRGALIGSGSFGQVYLGMNaSSGELMAVKQVILDSVSESKDrhakllDALAGEIALLQELS--HEHIVQYLGSNLN--- 468 Schizosaccharomyces ... P23647 4 YAVSSLVGQGSFGCVYKATRkDDSKVVAIKVISKRGRATKEL------KNLRRECDIQARLK--HPHVIEMIESFES--- 72 fruit fly
5O91_A 100 DQYIYMVMEWGNID-----LNSWLKkk------ksIDPW-------ERK-SYWKNMLEAVHtihqhgivhsdlkpanfl- 159 human P32490 292 NSSIYIAMEYMGGRsldaiYKNLLErg------grISEK-------VLG-KIAEAVLRGLSylhekkvihrdikpqnill 357 Saccharomyces cerevi... P06784 264 NNEIIILMEYSDCGs----LDKILSvykrfvqrgtVSSKktwfnelTIS-KIAYGVLNGLDhlyrqykiihrdikpsnvl 338 Saccharomyces cerevi... P10506 132 KNNISLCMEYMDCGs----LDAILReg------gpIPLD-------ILG-KIINSMVKGLIylynvlhiihrdlkpsnvv 193 Schizosaccharomyces ... 4UY9_A 80 EPNLCLVMEFARGGp----LNRVLSgk-------rIPPD-------ILV-NWAVQIARGMNylhdeaivpiihrdlkssn 140 human P17801 599 GSHRLLVSEYVENGs----LANIL-----------FSEGgnilldwEGRfNIALGVAKGLAylhheclewvihcdvkpen 663 Zea mays Q03497 687 KGDLWVIMEYMEGGs----LTDVVth-------ciLTEG-------QIG-AVCRETLSGLEflhskgvlhrdiksdnill 747 Saccharomyces cerevi... P27636 92 SYELYILLEYCANGs----LRRLISrss-----tgLSEN-------ESK-TYVTQTLLGLKylhgegvihrdikaanill 154 Saccharomyces cerevi... P28829 469 SDHLNIFLEYVPGGs----VAGLLTmy------gsFEET-------LVK-NFIKQTLKGLEylhsrgivhrdikganilv 530 Schizosaccharomyces ... P23647 73 KTDLFVVTEFALMD-----LHRYLSyn------gaMGEE-------PAR-RVTGHLVSALYylhsnrilhrdlkpqnvll 133 fruit fly
5O91_A 160 -----------ivdgmlklidfgianqmqPDTTsv----vKDSQVGTVNYMPPEAIkdmsssrengKSKSKiSPKSDVWS 224 human P32490 358 -----------nengqvklcdfgvsgeavNSL--------ATTFTGTSFYMAPERI----------QGQPY-SVTSDVWS 407 Saccharomyces cerevi... P06784 339 ----------inskgqiklcdfgvskkliNSI--------ADTFVGTSTYMSPERI----------QGNVY-SIKGDVWS 389 Saccharomyces cerevi... P10506 194 ----------vnsrgeiklcdfgvsgelvNSV--------AQTFVGTSTYMSPERI----------RGGKY-TVKSDIWS 244 Schizosaccharomyces ... 4UY9_A 141 ililqkvengdlsnkilkitdfglarewhRTT--------KMSAAGTYAWMAPEVI----------RASMF-SKGSDVWS 201 human P17801 664 i--------lldqafepkitdfglvkllnRGGStq----nVSHVRGTLGYIAPEWV----------SSLPI-TAKVDVYS 720 Zea mays Q03497 748 -----------smegdikltdfgfcaqinELNLk------RTTMVGTPYWMAPEVV----------SRKEY-GPKVDIWS 799 Saccharomyces cerevi... P27636 155 -----------sadntvkladfgvstivnSS---------ALTLAGTLNWMAPEIL----------GNRGA-STLSDIWS 203 Saccharomyces cerevi... P28829 531 -----------dnkgkikisdfgiskkleLNSTstktggaRPSFQGSSFWMAPEVV----------KQTMH-TEKTDIWS 588 Schizosaccharomyces ... P23647 134 -----------dknmhaklcdfglarnmtLGTHv------LTSIKGTPLYMAPELL----------AEQPY-DHHADMWS 185 fruit fly
5O91_A 225 LGCILYYMTYGKTPFQqiiNQIsklhAIID----------------------PnheiefpdIPEKDLQDVLKCCLKRDPK 282 human P32490 408 LGLTILEVANGKFPCS----SEkmaaNIAPfellmwiltftpelkdepesniI---------WSPSFKSFIDYCLKKDSR 474 Saccharomyces cerevi... P06784 390 LGLMIIELVTGEFPLGghnDTPdgilDLLQrivneps---------prlpkdR--------IYSKEMTDFVNRCCIKNER 452 Saccharomyces cerevi... P10506 245 LGISIIELATQELPWSf--------sNIDDsigildllhci----------vqeepprlpssFPEDLRLFVDACLHKDPT 306 Schizosaccharomyces ... 4UY9_A 202 YGVLLWELLTGEVPFRgidGLAvaygVAMNklalp-----------------------ipstcPEPFAKLMEDCWNPDPH 258 human P17801 721 YGVVLLELLTGTRVSElvgGTDevhsMLRKlvrmlsaklegeeqswidgyldsklnrpvnyvqARTLIKLAVSCLEEDRS 800 Zea mays Q03497 800 LGIMIIEMIEGEPPYL------------NEtplralyliatn----------gtpklkepenlSSSLKKFLDWCLCVEPE 857 Saccharomyces cerevi... P27636 204 LGATVVEMLTKNPPYHnltDANiyyaVENDtyyp-------------------------pssfSEPLKDFLSKCFVKNMY 258 Saccharomyces cerevi... P28829 589 LGCLVIEMLTSKHPYP----------NCDQmqaifrigen--------------ilpefpsniSSSAIDFLEKTFAIDCN 644 Schizosaccharomyces ... P23647 186 LGCIAYESMAGQPPFCassILHlvkmIKHEdvkw-------------------------pstlTSECRSFLQGLLEKDPG 240 fruit fly
5O91_A 283 QRISIPELLAHPYV 296 human P32490 475 ERPSPRQMINHPWI 488 Saccharomyces cerevisiae S288C P06784 453 ERSSIHELLHHDLI 466 Saccharomyces cerevisiae S288C P10506 307 LRASPQQLCAMPYF 320 Schizosaccharomyces pombe 972h- 4UY9_A 259 SRPSFTNILDQ--L 270 human P17801 801 KRPTMEHAVQtlls 814 Zea mays Q03497 858 DRASATELLHDEYI 871 Saccharomyces cerevisiae S288C P27636 259 KRPTADQLLKHVWI 272 Saccharomyces cerevisiae S288C P28829 645 LRPTASELLSHPFV 658 Schizosaccharomyces pombe 972h- P23647 241 LRISWTQLLCHPFV 254 fruit fly
Jiyao W et al.(2023). "The conserved domain database in 2023.",