Conserved Protein Domain Family
Peptidase_S39

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pfam02122: Peptidase_S39 
Peptidase S39
This family contains polyprotein processing endopeptidases from RNA viruses.
Statistics
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PSSM-Id: 111059
View PSSM: pfam02122
Aligned: 15 rows
Threshold Bit Score: 162.548
Threshold Setting Gi: 123874929
Created: 14-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123874929  363 KREFAWIPESGKYWADEDEDELPPPPKLVGGKLVwenAQETVAVENLNCQRAAGSRpl-----pPSLNLHATSSakEKSP 437
gi 123832995  218 VQGFKSFAVPMSPPGHSVLEIVHPDDSHMGYASC---VRLKNGEEALMTSVHCISD--------SFKVRSFRNG--IKIP 284
gi 81973566   208 VAGFDSYSIPQSPPKKSVITLRRADKTHVGFAVC---IRLFNNSNALVTSEHNLRE--------ADAFYSPRTG--RAIK 274
gi 137331     206 IDGFKSFTIPQSPPKSCVIPITHASGNHAGYASC---IKLYNGENALMTATHVLRDc-------PNAVAVSAKGlkTRIP 275
gi 82058478   202 VKGFLTFTIKQSPPRNCILQIQHADGSHAGYATC---VTLFDGTNGLLTAQHVVDDfyegdprkTLKVVSTRNG--NKIP 276
gi 82051831   202 VEGYLSFKIPQNPPKNSVLQVQYKDGSHAGYATC---VTLYNGTNGLLTAYHVAVP--------GSKVVSTRNG--NKVP 268
gi 81952328   202 VEGFLSFKIPQSPPKNSVLQVQHPDGSHAGYATC---VTLYNGTTGLLTAQHVVSS--------GCKVVSTRNG--NKIP 268
gi 123878581  218 TKGFGSYDMIMSPPKSCVLEMLHDDEQHCGYASC---ILLADGTVGLLTSYHVMEE--------AYWVKSNKTG--NKIK 284
gi 75568394   318 IPGVQIKKLREDPPKGVILRCTDQFGDHVGYASA---VKLEKGQTGIVLPIHVWTD------------TVYINGpnGKLK 382
gi 81997467   212 VRGFTTWAVPMKPPKNSILLISHDDGSHAGYATC---VTLHDRQSTTIGLITCSHA--------PINGSVFSTVtgNKIK 280
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 123874929  438 LpkACHSDLLGERLAS---LESCvEKILQKMSCEQYLPSQSSQTTLGQSEAPKLSL---APCYYKQesliLPES----Q- 506
gi 123832995  285 L--TEFQVLLPANVMDivlLRGP-PEWKSILGAKAAHFTPVNQLNKGAVSFFIFDKe--WMMHNAK----ITGT----D- 350
gi 81973566   275 L--AEFKVIFKDADLDvaiVAGP-DNWESAFGCGSVHFTTHDRLAKCPAQIYVIDGe-dWRAHSAK----VVGH----F- 341
gi 137331     276 L--AEFKTIAKSDKGDvtlLRGP-PNWEGLLGCKAANVITAANLAKCKASIYSFDRd-gWVSSYAE----IVGS----E- 342
gi 82058478   277 L--DEFRVTYTSEKRDqllMHGP-PNWEGVLACKAVHMIPASSVAKSKATFFALSDg-eWHSSNAE----LVGT----Sk 344
gi 82051831   269 L--SEFRSIMESEKRDlvlLAGP-PNWEGTLACKAVQFQSAQNLCKSKASFYAYDGe-gWISSNAE----IVGIa---E- 336
gi 81952328   269 L--SEFKVEIESPTRDlmlMTGP-PNWEGTLACKAVNFQTASNLCKSKASFFTFNGe-aWESSNAE----ITGIspcrK- 339
gi 123878581  285 T--SDFRPLTQSQNADlsiLVGP-PNWQGLLGCSAAQYVTVKHLAAGDARIF-YRKngeWYSGVAK----LVGP----H- 351
gi 75568394   383 M--ADFTALYEVTNHDsliMTSAmAGWGSILGVRPRPLTTIDAVKLKNYSLFTERDg-kWYVQAAKc---IAPA----E- 451
gi 81997467   281 M--ESFKTLYDDAETDvkiLFGP-PNWESVMGCKALKLVTRDSLAKGPATIYTFGDn-gWTSSQAS----ISGA----Y- 347
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 123874929  507 -QT-LKELVKTSLSATPPPNPVAALdQKPGPSTQS-LKKSVRRRNRR-KSTKKPAQGSPSPA----SPPPTKTS 572
gi 123832995  351 -GF-YATVLSNTEKGYSGAPYWNGK-SIVGVHKGH-VYGDDSKNYNL-MSPIPPVKGLTAPNfvyeSPSLQGDS 419
gi 81973566   342 -DN-FAQVLSNTKPGFSGAGYFHGK-TLLGVHKGH---AGKDYNFNL-MAPLPAIPGLTSPKyeieSDPPQGLI 408
gi 137331     343 -GT-DVMVLSHTEGGHSGSPYFNGK-TILGVHSGAsATG----NYNL-MAPIPSLPGLTSPTyvfeTTAPQGRV 408
gi 82058478   345 cGK-FISVLSDTKSGHSGTPYFNGK-SVLGVHIGS-PKEFESENVNY-MSPIPRFPGLTSPNyifeTTALAGKF 414
gi 82051831   337 -GKtHASVLSNTDAGHSGTPYFNGR-TVLGVHVG----GAKDENFNY-MAPIPPVYGLTSPSyefeTTAPQGRL 403
gi 81952328   340 ----FVSVLSNTDPGHSGTPYFNGK-TLLGVHIGG--AKEENANY---LAPVPPRAGLTTPNyvfeTTAPQGRI 403
gi 123878581  352 -KLnFVNVLSNTEPGFSGTPYFSGN-KIVGVHTG----GDEEENRNY-MAAIPHLEGLTASKyiyeTTAPKGRI 418
gi 75568394   452 -GM-F-RVVSDTRPGDSGLPLFDMKmNVVAVHRGTwPSERFPENRAFaILPVPDLTSSSSPKftgcETYSEAET 522
gi 81997467   348 -DKnKASVLSITDKGHSGAPYISGK-NVIGIHSG----GDIVDNVNV-CSTIPKIVNLTTPQlvfeTTAPQGRL 414
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