Conserved Protein Domain Family
DUF1256

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pfam06866: DUF1256 
Protein of unknown function (DUF1256)
This family consists of several uncharacterized bacterial proteins which seem to be specific to the orders Clostridia and Bacillales. Family members are typically around 180 residues in length. The function of this family is unknown. These proteins are related to peptidase family M63 and so may be peptidases.
Statistics
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PSSM-Id: 115518
View PSSM: pfam06866
Aligned: 13 rows
Threshold Bit Score: 184.398
Threshold Setting Gi: 81530172
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81480170   3 FINIEDKNAFENFYRTFQFYFKNLykepYREIILLCIGTDRSTGDSLGPLTGHKLKPLLRNKAHVFGTLEDPLHAKNIID 82
gi 586851    17 YVSHTDAAAAKQIQTILSSSLRKAa---GKPIVVVCIGTDRSTGDSLGPLVGMKLKQMQLTRFHVYGTLSDPVHAVNMKD 93
gi 81529119   6 VFNVDDSNILYSFSNYLSSEIKSIa--vNRDIVFLCIGTDRSTGDSLGPMVGYKLTKFHKNNLIVFGTLQEPVHAKNLCN 83
gi 75543309   6 IINSNSKSAIITLRDTLCGYITPVla-sGKHIILLCIGSDRSTGDSLGPLVGHNLKFLSRNNFHVFGNLEMPVHAKNLHQ 84
gi 81766312   6 YINSLDPKASFKIRDYLCRELSPVik-eNRPIVFICIGSDRSTGDALGPLIGEKIKFLSKNNIFIYGTLEETVHAGNLKE 84
gi 81530171  17 FSYNVDKENIEHWISAILFQVLKD----KEDIVILSLGVDTLVGDSLGPLVGSILKRNGIP--NVYGTLDRTVNASNIIK 90
gi 81530172   4 EKYYYEKNIQEEFFKFLYSMTGK-----KEEIVVICIGDPVFEGNILAPLVGTLLHERNIP--NVYGTLKEPVYEINIKE 76
gi 81482660   5 RLRYNEEKASFQIANFLSRHL-------LPETVFLCIGTDRFITDSLGPIVGNLISGSLPPIYYVYGTLKNPVHAINLEE 77
gi 75543171   5 MVHYNDPLAYKIMGETLSNFL-------NNNTIIVCVGTDKCIGDSLGPITGTILKEKNFP-LPVFGTVENPIHALNIKV 76
gi 81766645   5 KIYYKNYLAYYEISNFLKNHI-------DEKTIIVCIGTDKCIGDCLGPLVGTLLKEKFFP-LKVFGTLDSPIHALNLDK 76
gi 81529570   5 KAFYNLPMAYYRLSNFLKHYI-------DDNTIIICIGTDRCIGDCLGPMVGTMLKEKFFP-LNVYGTISEPIHALNIDK 76
gi 81744947  15 RLHYKENN----LPSLMCQHIMNWfpyqPREYVAVFIGTDRSTGDALGPLAGMYFQSYKPRHIRVYGTIHEPVHAVNLEE 90
gi 81785277  15 RVHMDDPQASDQLVEQLLTHVSSYr---HRELVIVCIGTDRSTGDALGPIVGTALTKECLNCFHVYGTLADPVHAVNLEE 91
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81480170  83 VLKEIRNTFYMPFTIAIDASLGSL--KHVGHISIGKGPIKPGAGVSKELPPVGDMFVTGIVNISGFMEYM---VLQNTRL 157
gi 586851    94 KINDIHKLHKNPFVIAVDACLGRV--KSVGSFQIGDGPLKPGAGVQKDLPEVGDLHINGIVNVSGFMEYF---VLQNTRL 168
gi 81529119  84 TMDIIKTKYENPFIIAIDACLGST--KTVGNIVIQNTPLSPGSAMNKSLPTVGDLSITGIVNVSGPFDFM---VLQSTRL 158
gi 75543309  85 ILKYINKKFDDPYIIAVDACLGHI--QNIGKVFVEDKPLKPGSAVNKDLPPVGNLSITGIVNISGTLEFM---VLQNTRL 159
gi 81766312  85 TVKIIKSKHKKPFIIAIDACLGAV--DNVGHVLIEKRPLKPGIALNKDLPEVGDLSILGIVNISGSLEFM---VLQNTRL 159
gi 81530171  91 ILDEIHERFKNPYILVVDAAVTAE--NNINDIVLRNGGFTPGFGVYRQLPTVGDFSLVGVVNKEDEREHNlieLLKKCRF 168
gi 81530172  77 IYNKILKKYDNPYIILVASSFPVDfhDEREVIVLKNDPYEIQTASGS--LKLGNASFIVVFDLEDS--YCkvnFIEKLGI 152
gi 81482660  78 NLRYIKKKHPYSKIIAVDASLGEE--ENIGKISIKKSPIHPGKGVGKILPPVGDLSIVGIVDSFHAKDLN------SIRL 149
gi 75543171  77 KMSEIASLYPNHNIIGIDACLGES--NNIGFIQSRNYPIYPGKGVGKKLPHVGNHSIVGIVDSTEINIFN----NNSIRL 150
gi 81766645  77 KITEILKTYPGYKILAIDACLGDS--NSIGEIHARNEPIHPGKGVGKSLRSVGDMSIIAIVDSSENIDLF---TSRPIRL 151
gi 81529570  77 KLYKIKKDHTNSTIIGIDACLGDT--ENIGEIQVRDYAIHPGKGVGKSLPDVGEVSIVGIVDSCESSELF---TNRNIRL 151
gi 81744947  91 SLERIDKLHNNPFIIAIDACLGRS--TSIGHIITEKKSLQPGTALNKTLPAVGDVSITGVVNVSGFMEHS---ILQNTRL 165
gi 81785277  92 KLKLIEKKHRRPFIIAIDACLGKL--SSVGKVSLAAGPVQPGAAVNKKLPAVGDVHLTGIVNIGGMMEYF---VLQNTRL 166
                       170
                ....*....|...
gi 81480170 158 RTVMKMADIIAAG 170
gi 586851   169 NLVMNMANVLAEG 181
gi 81529119 159 YSVLKLADIISRG 171
gi 75543309 160 FTVMQLAELISNG 172
gi 81766312 160 YTVMLLANAISNG 172
gi 81530171 169 DEVLKLARIISKI 181
gi 81530172 153 RKIYKYSEAIFKT 165
gi 81482660 150 GFIYEIAETIANG 162
gi 75543171 151 NFILNMAKSISHS 163
gi 81766645 152 SFILDMSKVIVDS 164
gi 81529570 152 NLIFEMSKVIVQT 164
gi 81744947 166 SVVMDMAKQVSSI 178
gi 81785277 167 HTVMQLADTISSS 179
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