Conserved Protein Domain Family
BRAP2

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pfam07576: BRAP2 
BRCA1-associated protein 2
These proteins include BRCA1-associated protein 2 (BRAP2), which binds nuclear localization signals (NLSs) in vitro and in yeast two-hybrid screening. These proteins share a region of sequence similarity at their N terminus. They also have pfam02148 at the C terminus.
Statistics
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PSSM-Id: 311505
View PSSM: pfam07576
Aligned: 37 rows
Threshold Bit Score: 118.048
Threshold Setting Gi: 367000547
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 3219947     84 APGLILAILAIPLYMSPSDVLGFL---GeKHCKSIQHIRLLKTKDPN------RIMALLKFKDQASVIRFYTEFNGKAFS 154
gi 39932541   154 AQCRMLCMYAVPAQVEVREIISFM---C-ISLPMIVSIKVVRDPAPN------QYMLIIKFKEHNDAVTFYEEFNNCPFN 223
gi 780086006  292 VRSDMICALAVPASLICHDLLQFF---S-PLAEGIEHIRIIRDSNPN------QYMTLIKFRNQSHADEFYKEYNGKPYN 361
gi 196010784   37 lRSEMLCMLAVPATMSCNDLIQFA---A-PYSPNIEHIKIIRDSTPN------EYMVLIKFKDQTCSDEFFKLYNGRTYH 106
gi 156355402   36 SRSQTICMLAVPAKLTCIDLLQFV---A-PSEEFIENIKIIRDASPN------QYMALIKFKNQ--AHEFYNTFNGQQYN 103
gi 405967898  151 pRSELVCMLAVPAAYTIHDLVKFT---A-PVGEGIEYMRIIRDSTPN------QYMVLIKFRTQRLADEFFTTYNNVSYN 220
gi 290976595  164 ERSRLVSILAVPSFISIADFFEFI---A-CFECNIEKTRILRDESPN------KYMVLLQFDEQRNADSFFVQYNGRPFN 233
gi 541041305  175 AKCSMLCMLNVPSLITCRELLKFV---S-PCLQSISAMKIIRDMTPN------QYMVILKFKSHEATVSFYRECNDTRFN 244
gi 367000547   95 GDDSMVCMLFVPSYFTLHELLHFYigdD-IINTKVSNIRMLKHYKKNanilgcNFMVLLKFKDPIYAKEFLNEFNGKKFS 173
gi 1034581711   9 RRSAMLCILTVPAAMTSHDLMKFV---A-PFNEVIEQMKIIRDSTPN------QYMVLIKFRAQADADSFYMTCNGRQFN 78
                          90       100
                  ....*....|....*....|..
gi 3219947    155 QIDPETCHVLHIDKVNIKYPME 176
gi 39932541   224 DLESYCCTLFFVDRIECTTSND 245
gi 780086006  362 SFDDFVCYLVFVSRVECMKSCE 383
gi 196010784  107 SLEDKICHLVYVSLVETMTSTE 128
gi 156355402  104 SFEEEVCHLVYVAKVEIVKSSE 125
gi 405967898  221 SIEPDICQLIYVARVEVIKDSE 242
gi 290976595  234 SLDPEHCKIVFVKSVEFTSRPD 255
gi 541041305  245 QIEPERCSLVFVERIESTREea 266
gi 367000547  174 KMDPETCHIVAIKELVFKKTLF 195
gi 1034581711  79 SIEDDVCQLVYVERAEVLKSED 100
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