Conserved Protein Domain Family
Kazal_2

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pfam07648: Kazal_2 
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Kazal-type serine protease inhibitor domain
Usually indicative of serine protease inhibitors. However, kazal-like domains are also seen in the extracellular part of agrins, which are not known to be protease inhibitors. Kazal domains often occur in tandem arrays. Small alpha+beta fold containing three disulphides.
Statistics
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PSSM-Id: 311539
View PSSM: pfam07648
Aligned: 50 rows
Threshold Bit Score: 32.2232
Threshold Setting Gi: 384482499
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*..
1TBR_R         60 CDGDEYK-PVCGSDDITYDNNCRLECASISS----SPGVELKHEGPC 101
gi 24212472   139 CPVAQSA-MVCGSDGHSYTSKCKLEFHACST----GKSLATLCDGPC 180
gi 94730393    87 CRCRWTH-TVCGTDGHTYADVCALQAASRRAlqvsGTPVRQLQKGAC 132
gi 17366421   108 CPTLGGA--VCGSDRRTYPSMCALRAENRAArrlgKVPAVPVQWGNC 152
1Z7K_B         22 CNKALN--PVCGTDGVTYDNECVLCAHNLEQ----GTSVGKKHDGEC 62
gi 1708509    307 CPFILQE--VCGTDGVTYSNDCSLCAHNIEL----GTSVAKKHDGRC 347
gi 341940715   56 CKPHKR--PVCGSNGKTYLNHCELHRDACLT----GSKIQVDYDGHC 96
gi 399021      97 CPATVA--PVCGSDASTYSNECELQRAQCNQ----QRRIRLLRQGPC 137
gi 23821567   123 CEGLPAGfQVCGSDGATYRDECELRTARCRG----HPDLRVMYRGRC 165
gi 120548     122 CSNITWKgPVCGLDGKTYRNECALLKARCKE----QPELEVQYQGKC 164
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