Conserved Protein Domain Family
7TMR-DISMED2

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pfam07696: 7TMR-DISMED2 
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7TMR-DISM extracellular 2
This entry represents one of two distinct types of extracellular domain found in the 7TM-DISM (7TM Receptors with Diverse Intracellular Signalling Modules) bacterial transmembrane proteins. It is possible that this domain adopts a jelly roll fold and acts as a receptor for carbohydrates and their derivatives.
Statistics
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PSSM-Id: 311568
View PSSM: pfam07696
Aligned: 243 rows
Threshold Bit Score: 38.8951
Threshold Setting Gi: 916315829
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2XBZ_B         36 WRLL--RD-----------ESAQLRIADVlqrkeqfrplakrsfifpaspqaVWLQVQLP-AQKVPSW-------LWIFA 94
gi 81465486    40 fVYYfsSDsdenfrerifaKDSSLSFQNIpaevfsl----------gftsntVWFYIPLKnDTEKDYRg-----eFEIFN 104
gi 503895701   47 LDVL--PG-----------ENGRVQISTApgedgiirrie--ivsiaeganpNWAVFALRnESDVQIErllvapyFRLPG 111
gi 939010126   43 VDIY--PN-----------TSKSIQVSTApdsdgivrri---evrsvddtasSWAVFALSnPGEEQIDrllvapyYKMTG 106
gi 506407308   44 IERY--RS-----------DGDLIQISTApgkdgivrria--vkaretgarpDWIVFALTnDTDEQIDrllvaphFRLVG 108
gi 501352091   33 VVSY--RS-----------EGDRLQVSTApgsdgivrrie--vsareagtqpSWIVFALTnDTDEQIErlivaphFRLVG 97
gi 154160436   53 VQRE--TT-----------EDGRFQISTApdaegvvrrie--vptsdgrshgDWIAFALTnNTDEQVDrlivaphYRMSG 117
gi 501119793   43 VERL--HT-----------DNERVQISTApgtdgivrrie--vrssdgqpnaNWVAFALSnNTDEQVDrlivapfYRMVG 107
gi 908641815   34 VERR--TS-----------ETDRIQVSTVpgadgivrrie-vrsvapgpngsKWAIFALAnNTDEQVDrlivaphYRMVG 99
gi 749827350   46 LEFQ--RS-----------DTDRIQVSTApgtdgivrri----evrareggqNWIVFALTnNTDDQLDrlivvphYRIVS 108
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
2XBZ_B         95 PRVQYLDYylv-qdGQLVRDQH---TGESRPfqerplpSRS----YLFslPVDGKPX-TLYVRXTSNhpLXAW 158
gi 81465486   105 SYLEEVDIfyrygsKDSIHEIL---AGTSRvy-----eKSFpalnFYL----RPGEEiQIVCKIKSGtpMRIP 165
gi 503895701  112 SGVFHPDL------GSARITALtpsHGLRPE-------RVPdseaDVFdvVIDPGATvTLVAELRSE--TLPE 169
gi 939010126  107 GGVLVPDL------GQRRIVSLtpsQGIPPI-------RERsteaDIYriTLDPGANvTFIAEVNTP--SLPE 164
gi 506407308  109 SGIIWPDL------GGSRIAAItasQGIRPE-------RDEspdaDQFtvTLDPGTTvTFVAELRTP--NVPQ 166
gi 501352091   98 SGVIWPDL------GATRISAItasQGFAPE-------REDnndaDVFrlTLDPGTTiTYVAELRTP--NLPQ 155
gi 154160436  118 SGLFWPDL------GNRRITSLtpsQGFKPE-------RQTapdaDVFliTLDPGSTvTFVAELGSP--TLPQ 175
gi 501119793  108 SGLFWPDL------GNRRVLSLtpsQGFKPE-------RQNapdaDVFlvTLDPGTTvTFVAELAGP--KLPQ 165
gi 908641815  100 SGVFWPDL------GNRRILNVtasQGFRPE-------RQNapdaDVFliTLDPGTTvTLVAELGDG--GLPQ 157
gi 749827350  109 SGLLWPDL------GLSRIASItpsTGDRPE-------RQDnataDVFriTLDPGAVvTYVAELRTD--KIPQ 166
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