4FXG,2B39,5A42,3CU7


Conserved Protein Domain Family
A2M_N_2

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pfam07703: A2M_N_2 
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Alpha-2-macroglobulin family N-terminal region
This family includes a region of the alpha-2-macroglobulin family.
Statistics
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PSSM-Id: 336775
View PSSM: pfam07703
Aligned: 627 rows
Threshold Bit Score: 44.1641
Threshold Setting Gi: 512909835
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4FXG_A        454 LSiE--RPDSrPPRVGDTLNLNLRAVGsGATFshyyymILSRGQIVfMNRepk---rtLtSVSVFVDHHLAPSFYFVAFY 528
gi 74840240   433 IK-LelKSP---INLNKLMRFIVTCTE-RMTFfv--yyVVSKSNIVdAGFvrpk-netTfLLQLYATEKLFPKAKMLVAT 504
gi 74804568   432 IK-IelKSP---IKLNKLMRFTVTCTE-RMTFfv--yyVVSKGNIIdAGFmrpn-krtKyLLQLNATEKMIPKAKILVAT 503
gi 568249958  437 LK-VamETP---LKLHHDISLLVTCSK-GTTFyl--yyVLSRGSIIdSGYvplgkglvShRLQLKPSDRMLPKSTVIVAT 509
gi 347972485  437 LR-Ah-KQA---VKIGKPFKLKVTCNE-ELSFfm--yyVVSRGVIVdSAFlqpk-kvtEhFIEIEASDQMVPRSKVIVVT 507
gi 568258430  429 IT-VqsNSS--NAGLNQKIKIDVACSD-HMTFla--yyVVSKRNIVdAGFirln-kvpKhRFQLVASGKMVPRSQIIVVT 501
gi 568248388  435 IE-IelKSP---AQLNKMLKAVVKCST-RGGFfa--yfVVAKGNIVeSGSyslg-qvtRhSIQFNVTEPMVPKFKIIVAS 506
gi 347972490  427 LK-LelKSP---IKLGKLIRLMVTCNE-RMTFfi--yyVISKGNIVdAGFvrpn-rqtKfMFQLTASEKMIPKAYIFVAT 498
gi 170028267  439 IT-VtlNENRyKVRPNREVLFEISCTE-RMSHfa--ytFWARGSIIdSGHvnva-nkkRySFRYRLLPQMAPKAKLIVTY 513
gi 170028269  436 II-S-------RVRPNKEVVFEVSCTE-RFKHfs--ytFVARGRIIdAGHvnvm-nkkKySFRYKLLAEMAPQAKLIISH 503
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
4FXG_A        529 y-hG-DHPvanSLRVDVQagaCEGKLELSV-Dg-AkqyRNGESVKLHLEtdsLALVALGALDTALYAA 592
gi 74840240   505 v-tG-RTVvydYINLDFQv--FHNNFTLSV-D--EqeiKPGRQIELSMSgrpGAYVGLAAYDKALLLF 565
gi 74804568   504 l-vN-RTMvndIVDIDFQg--FRNNFDLSI-D--EqeiKPGRQIELSMSgrpGAYVGLAAYDKSLLLF 564
gi 568249958  510 ivtAsQVVlydFVELDYQa--LRNNFTMKL-D--KtvlKPGQELRLRMTglaGSYVALAAYDKSLLQF 572
gi 347972485  508 v-aK-NVVlcdFVDIDFEd--LRNNFDLQI-D--RteiRPGDQLQLNMRgppGAFVALAAYDKSLLQY 568
gi 568258430  502 v-aN-NMIvhgYVNIEFEe--FSNNFDLRM-K--QnevSPGSQIELLVTgpqRAYVALASYDQSLLQH 562
gi 568248388  507 l-sN-NIIvydYVDVVVKe--FLNNFDIRIvAdkSdtfRPDNQIEFNLMgrpKAYVALASYDMSVLQH 570
gi 347972490  499 v-sQ-DVVvwdSLEIDLKq--FSNHLDIII-D--EkelKPGQEIELLLKgrpSAYVGLAAYDKGLLAY 559
gi 170028267  514 t-sK-NFLifdDLELNFDm--FSNHFEFSL-D--DddyLPGQDIYVDLQaanDSYVAFHAIDQSVLHL 574
gi 170028269  504 i-sR-DYLiydVLALDFDv--FNNDFEFFL-D--SdnyNPGQDVYVDMRavkDSYVAFHGIDQSVLHL 564
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