Conserved Protein Domain Family
A2M_N_2

?
pfam07703: A2M_N_2 
Click on image for an interactive view with Cn3D
Alpha-2-macroglobulin family N-terminal region
This family includes a region of the alpha-2-macroglobulin family.
Statistics
?
PSSM-Id: 311575
View PSSM: pfam07703
Aligned: 656 rows
Threshold Bit Score: 36.0575
Threshold Setting Gi: 0
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RTD_A          736 VTL-KLDKaSYRPGDTIKLHIAAPTAgkgyaxvESSEG------PLW--------WQEIdV-RA----Q---------Gl 786
64_pfamImport     1 VLVdTTSS-TSDNTGRVAFSVQTSR----------FQTalk-ikVIS--------RGQT-KaHGkvneSsf-----ykT- 53
520_pfamImport    1 LTL-VEKNdRFKVGDKYTNSIIFEG----------STF------IFSqayyitvvRGRI---------Dkler--ipdNd 52
550_pfamImport    1 LNVdVSTD----------FLIQRIGT-------TGDQDidlhflCIT--------GGKV-VlEGvqrsIsa-----agT- 48
476_pfamImport    1 INT-PMFGhSLRVSHYANIQVYTAAP-------SYLNIrtlnylVLS--------KGKV-VfFN----SqnfassvdsRq 59
gi 597759804    471 IDL-PSELsSFEVDSYANIKIYFSYRd-----yLPLKTfn--yqIVS--------KGKV-VkFA----Tvqrv--sekSq 527
gi 973205757    287 IDW-ASSHrVLHSGDYVSINIYFSQKh-----lSNIKYys--yqVIS--------KGKI-VaFNsm-sRvgq----anYq 344
gi 765131607    468 yintpmfgkSLVVGRDTQIQVQTASPs-----yLNIQAln--ylVLS--------KGKV-VfHK----SvdfvrsldgTn 527
gi 780180974    475 LSI-SIDQtVFRVGDE--LYVVARTTa-----sTPIDNln--llFLS--------QGKV-IlAK----Sidh----miNn 527
gi 675864482    283 LSA-KVLDdVLKPDKNTTFIVRTt---------EPIKYff--yqILS--------KGFI-SqAK----Vvks----dkAs 333
                            90       100       110       120       130       140       150       160
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RTD_A          787 --DL-TIPVDK------TWNRhDLYLs-TLV--V----RPgdksrsatP---KRavgVLHLPLG-DENRRLDLALet--- 843
64_pfamImport    54 ---F-GFQVTP------EMSP-GARV--LV---Ya--fHE--------G---HLladSMNIEVEeVCTGSSDIEIe---- 100
520_pfamImport   53 --NF-GFTIEP------HMAP-SFRLiaISYryD------------------RVvsdSLLINVDpP-----ECSLnltyt 99
550_pfamImport   49 --NL-AITIRA------YMAP-QMRL--IVY--Yv--tMD--------G---SViadSLLLGVEeKCRQDPQLSLdi--- 98
476_pfamImport   60 --NL-NFLVTA------SMVP-SIRL--LVY--YvldgEGt-------M---ELvadSVWMEVKdKCVNGLQTNIl---- 111
gi 597759804    528 --NI-NFKVTA------DMVP-SARL--LVY--Yi--lSG--------EqraELvadSVWLDIKaKCVNSLDVNLa---- 579
gi 973205757    345 --NI-NFRVNS------DMVP-SSRL--LVY--Yv--vTG--------EgeaELvadSVWMDVQdKCVNGLQAKIs---- 396
gi 765131607    528 --SL-NFMVTP------SMVP-SIRL--LVF--Yi--lHG--------EgtsELvadSVWIDVKhKCINGLETSVt---- 579
gi 780180974    528 peRV-FFSVSS------DMVP-MVRI--IAY--Yi--nQL--------D---QVvadSIALKIEnTCKHHVAINIk---- 578
gi 675864482    334 --SLhEFTIVPskqlalELAP-RVKI--LAY--Yv--nTK--------D---EVvadAMTVNVEdYLVNKLSIAFdkn-- 391
                           170       180       190       200       210       220       230
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4RTD_A          844 -------paK-----X------RPNQ-PLTVKI-------K---AstkngekpkqVNVLVSAVDSGVLNI 884
64_pfamImport   101 ---------Pe----Frs---eEPGS-SGVLNV-------RgreG----------TRVGILAVDKAVYIL 136
520_pfamImport  100 nskgatndiE-------------PGEnG-TLIVsanqsenR--------------RQISIVGVDEAVYLL 141
550_pfamImport   99 -------lpRnvgpeRdv---yEPNG-QIQVEV-------TapiD----------SNVGLLAVDKAVYLL 140
476_pfamImport  112 ---------Fq----Erl---yKPKE-NIKLDI-------RtnqG----------SMVALSAVDSAVFSL 147
gi 597759804    580 --------aT-----Dka---yKPKE-KLQLSV-------KtksDsl-------sSLVALSAVDMALYNL 618
gi 973205757    397 --------vP-----Pgv---yKPKE-KVDLKI-------EadeG----------SSVALSAVDTALYEL 432
gi 765131607    580 --------vD-----Tri---hKPKE-NLNIDI-------RanqP----------GLVALSAVDSAVYSI 615
gi 780180974    579 --------eE-----TneegayLPET-PVTLLV-------DaypT----------SYVGLLGVDKAVYAL 617
gi 675864482    392 --------------------stSPSK-PIVLNV-------EaekD----------SFVGIAAVDKSVLLL 423
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap