5KNE,1UM8


Conserved Protein Domain Family
AAA_2

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pfam07724: AAA_2 
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AAA domain (Cdc48 subfamily)
This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.
Statistics
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PSSM-Id: 336783
View PSSM: pfam07724
Aligned: 139 rows
Threshold Bit Score: 87.2514
Threshold Setting Gi: 75015142
Created: 23-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5KNE_A      601 QP-ASFLFLGLSGSGKTE---------LAKKVAGFLFnd---------edMMIRVDCSELSE----KYAVSKLLGTTAGY 657
gi 32129621 200 NSeVTIEMDDPQQAAAGNnn------mLGQMGIDLGDslgalmpkkriqrTMPVSEAREILVreesEKLVNNADIYHDAI 273
gi 11133033 193 NEeVTIEVEQAPKA-NPMgd------mMGQMGMDMSSmlgdmlpkkkvkrTLPVSQARKLLVqeeeKKLVNYDDIYQKAM 265
gi 21759169 196 DEiVTVEVKEQQ---NPMldmm-rgagMDQMNGMQDAlsgmfp-akkkkrKVTVREAKKILFedeaSKLIDADELAAEGI 270
gi 22653791 187 NHmVEIEVTDTT---PPMlemy-tnlgAEELNITLQDmfsdllpkkkklrKVTVAEAKKILEaeeaQNLIDMDEVIEEAV 262
gi 81832890 166 HLkIEIQPPKKSV---DFsegn-vppeIVRIQESLAKaflnsq-keemkkEVTVKEAKELLKieasEALLDMETIKAEGL 240
gi 81835992 170 DLmIEIEISKKPI--SQFnden-mppdMIKVQESIFKvlnvsq--dkikkEMSVKEAKEALAyeaiESVLDAESIRAEGL 244
gi 11132784 171 SReIEIEVRKKSI---EIdsnv--ppeILRVQENLIKvfhkeq--dkvkkTLSVKEAKEALKaeisDTLLDSEAIKMEGL 243
gi 11132844 177 DRiVEIEVKEKT---VPMvgia-gppgLEELENQIKEmlsgli-pskrrrKVKVKEALQILEqeeaEKLIDMEEVAREAI 251
gi 32129636 208 DRqIELEVSSDGQ--GGMmqifgplgqMEEIGNIMQDlmsgmp-kkrkkrRMTIAEARKYLEqeevQKLIDMDAVVKEAL 284
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5KNE_A      658 VGYDEGGfltnqlqykpysVLLFDEVEKAHP---------------DVLTVMLQMLDDGRITSGQGkTIDCSNCIVIMTS 722
gi 32129621 274 VRAENTG------------IIFIDEIDKITKggqqgs---gevsreGVQRDILPIVEGSQISTKYG-PINTDHILFIASG 337
gi 11133033 266 DRAGQSG------------IIFIDEIDKITAadkrns---agvsreGVQRDILPIVEGSTVSTKYG-PLSTDHILFIAAG 329
gi 21759169 271 HRAEQMG------------MIFIDEIDKIASkegggn---aqvsreGVQRDILPIVEGSQISTKYG-TVNTEYILFIAAG 334
gi 22653791 263 KRAENDG------------IIFIDEIDKIAStgysag---pdvsreGVQRDLLPIIEGCTVMTKYG-PVKTDYILFIAAG 326
gi 81832890 241 RRAEEEG------------IIFIDEMDKIAVsqgsssr--qdpskeGVQRDLLPIVEGSTVSTKHG-QIKTDYILFIAAG 305
gi 81835992 245 RRAQENG------------VIFIDEIDKVAVgskdgsr--qdpskeGVQRDLLPIVEGSVVNTKYG-QIKTDYILFIAAG 309
gi 11132784 244 KRAESSG------------VIFIDEIDKIAVsskegsr--qdpskeGVQRDLLPIVEGSVVNTKYG-SIKTEHILFIAAG 308
gi 11132844 252 YRAENFG------------IIFIDEIDKIAVktpgag---pgvsreGVQRDLLPILEGTTVNTKYG-PVKTDHILFIGAG 315
gi 32129636 285 RKVEDSG------------IVFIDEIDKIAApttgaggkgpdvsreGVQRDLLPIVEGTAVSTKYG-VVKTDHVLFIASG 351
                       170       180       190       200
                ....*....|....*....|....*....|....*....|..
5KNE_A      723 NLGAEFINSqqgskiqestknlvmgavrqhFRPEFLNRISSI 764
gi 32129621 338 AFAESKPSD---------------------LIAELQGRFPIR 358
gi 11133033 330 AFAESKPSD---------------------LIPELQGRFPIR 350
gi 21759169 335 AFHMSKPSD---------------------LIPELQGRFPIR 355
gi 22653791 327 AFNVAKVSD---------------------LIPELQGRFPIR 347
gi 81832890 306 AFHLSKPSD---------------------LIPELQGRFPLR 326
gi 81835992 310 AFHLSKPSD---------------------LIPELQGRFPLR 330
gi 11132784 309 AFHLSKPSD---------------------LIPELQGRFPLR 329
gi 11132844 316 AFHMAKPSD---------------------LIPELQGRFPIR 336
gi 32129636 352 AFHVARPSD---------------------LIPELQGRFPIR 372
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