Conserved Protein Domain Family
ERp29

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pfam07749: ERp29 
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Endoplasmic reticulum protein ERp29, C-terminal domain
ERp29 is a ubiquitously expressed endoplasmic reticulum protein found in mammals. ERp29 is comprised of two domains. This domain, the C-terminal domain, has an all helical fold. ERp29 is thought to form part of the thyroglobulin folding complex.
Statistics
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PSSM-Id: 311614
View PSSM: pfam07749
Aligned: 160 rows
Threshold Bit Score: 60.6328
Threshold Setting Gi: 855315716
Created: 19-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2C0F_A       139 GCIKEFNEVLKNYAN-IPD--AEQLKLIEKLQAKQE--QL-T-DpEQQQNARAYLIYMRKIHEVGyDFLEEETKRLLR-L 210
gi 549043377 265 GRIAAFDDEVAKLVK-GDA--ESLKTVTEAVEKLAE--EA-K-E-T---YASYYLKALKKVADKe-GYVEKEIARLQKmL 332
gi 831347942 264 GIIDAFDKVIKKLGG-TTN----VAEITAEATKIAQ--EL-Q-HtAEKKYAKYYVKVFAKLSESk-EYAAKELARLQGlL 333
gi 528301130 267 GIIKSLDLFVSEFID-GSD----ISEIANKVSQAVQ--GI-EsN-SENRFAEYYVKVFQKLEKDG-EYVARELDRLNKiI 336
gi 501754505 136 GRVPSLDAISKKIGGgATG--EKLVRLLEEGRTAVD--EYaK-S-ASDEGYKYYYKVLDKLATNd-GFVKSEYARLTGiL 208
gi 748510472 272 GTIGLLDEMIKEKL----P--KGLAGIAAEFEDAAK--LV------EDKYAKYYINVAKKLQGKAt-YVTDELARLGKlI 336
gi 855312302 262 GRIAEVDEVLQK-----AE--GFSEELQKEVEAILE--KT-E-A-KVAESKRIYASILKKIAEKGeKYVQDERARLTKfV 329
gi 299473308 268 GRLEVLDAVLASRSG-LADplAGLKASLEEAAAKAGygEE-G-S-DAAASAGHYARAAQKLSEKGnGYLAKELKRLEGlL 343
gi 629661251 264 GTIDIMNHIALQYAA-GT---EKLADLAAQAKKAAE--DL-GeE-AQYAYAKYYIRVFDKLAENE-GYVAKESARLNNiL 334
gi 550810206 263 GTIEALDELVAKFAA-GR---ATLTEAAKDVKKAAN--AL-QgQ-VGGKFAEYYVRVFDKLSAND-GFVAKELARLESiL 333
                         90       100
                 ....*....|....*....|....*....
2C0F_A       211 kAG------KVTEAKKEELLRKLNILEVF 233
gi 549043377 333 kGG------KIAQKKSDELWSKVNILGQF 355
gi 831347942 334 nKG------NLAKVKEDEMTAKSNILKTF 356
gi 528301130 337 iKG------GVTTQKLDEFTSKINILKSF 359
gi 501754505 209 kKSr----tTMAKELVDEMRKKVNILSAF 233
gi 748510472 337 tGG------NLHADKVDDFTKKQNILKRF 359
gi 855312302 330 eGE------NIAPLKKGLFRIRLNILDAF 352
gi 299473308 344 gGGgggggaTISAQKRTLFMVRSNILRAf 372
gi 629661251 335 kKG------GLAPAKLDELQSKSNILKKF 357
gi 550810206 334 gKG------GLAPTKIDELTSKSNILRKF 356
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