1JJI,3WJ1,4OB7


Conserved Protein Domain Family
Abhydrolase_3

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pfam07859: Abhydrolase_3 
Click on image for an interactive view with Cn3D
alpha/beta hydrolase fold
This catalytic domain is found in a very wide range of enzymes.
Statistics
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PSSM-Id: 336840
View PSSM: pfam07859
Aligned: 103 rows
Threshold Bit Score: 155.436
Threshold Setting Gi: 81841635
Created: 20-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JJI_A        82 LVYYHGGGFV---ICSIESHDALCRRIARLSNSTVVSVDYRLAPEHKFPAAVYDCYDATKWVAENAeelrIDPSKIFVGG 158
gi 81841635  133 VMFLHGGGFI---NEIVPAHWRLIGQMTREARVVCVVPIYPLAPRVTAKDVVPATAELLRMLLED-----AGPAKVTVVG 204
gi 81819342   78 ILYLHGGYNT---LQPSPFHWRLLDKLTLNTLHEVVLPIYPKSPDYHYLETFKAIRDVYNQLVEE-----VGANNIVMMG 149
gi 81855655   72 LFYAHGGGFL---GGSIYTHRKLVGHLAKAVGCRALLYGYPLASQAKYPAQLEAAMAAWDWLIDQd----FDTRRIALAA 144
gi 81860439   88 LIELHGGGFVmgsAASFGLMEAIPV--AAMTGITVVAVDYRMGPEHQFPAASEDVAAVYRAALKT-----YTPAQVGLFG 160
gi 81858402  124 LLHLHGGGYVl-gAGESGTLEAIFM--AGIGGYRIVSVNYRMPPDHPYLAAMDDALAVYRELLKT-----TPAQNIGVFG 195
gi 81817766  103 WVHLHGGGYAl-aGGELGTGEAVLA--AHYGQVGVISIDYRQPPNYPFPAALEDALVMWQELVKT-----HDVNRLALFG 174
gi 81840019   47 VMYIHGGAYI---VGHPDGYHGIGGNYAKMLGARVYMPDYRLAPEHKFPASIDDTLRAYEWLLEQK----IPANKIAFSG 119
gi 81817126   73 VLYAHGGFFI---SGSPMASRALCASLADEVGAKFYIPAYQLAPEHPFPAALENMYDAYVALIDQk---kFRPEDIIFSG 146
gi 499210126  94 VLYLHGGAFL---GCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQWLRRLg----YDPEQIVLAG 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1JJI_A       159 DSAGGNLAAAVSIMARDSgedfIKHQILIYPVVnfVAPTPSLle---fGEGLWiLdqk--imsWFSEQYFSr--EEDKFn 231
gi 81841635  205 NSAGAGLALAACQWLRDRghrqPNLMVLISPAAdaSVSRPEQvei-aaRD-PM-Qdip--gilEAGRLYAG---ELDVGh 276
gi 81819342  150 DGSGGGLALSFVQSLINDnqevPRKLFLLSPLLdaTLTNPNItkt-leENDIL-Vsrf--gvhQLMKSWTN---DLPLSd 222
gi 81855655  145 DSCGAVLTYGVLQRLRAQerplPAATLIISGWFdmALTAASYetn-reKD-PF-Fakg--gvdWLVTSFIG---DYDRLd 216
gi 81860439  161 CSAGGVLTGEALAWFAKEqlpmPAAAGLFCAAGdaRYRGDSQrvvaavND-AL-LpdvagtlpIMEDLYYGp--DVDFRd 236
gi 81858402  196 TSTGGGMTLALVLRARAEglplPAAIAPGTPWTdlTKTGDSYftn-egvD-NI-LvsydgwlgDAARLYAA---GHDLKd 269
gi 81817766  175 TSAGGGLLLALVCQLRQLnlplPAAIAPLSPWVdlTKTGDTHftn-eyvD-RT-AisydglieGLARLYAG---ELPLTh 248
gi 81840019  120 ESAGGAMVVSVMVAAKSKglplPAVGSSISPWAnlEHTGTSMsnr-egLD-PL-Nskp--vldILARAFLG---DTLANh 191
gi 81817126  147 DGAGAGLMLALTHYLKQKglvcPRALALISPWVdlTEDRFAGegv-kkKE-LL-Ltrd--mfrYCALQYTY---ADNFRn 218
gi 499210126 167 DSAGGYLALALAQRLQDVge-ePAALVAISPLLqlAKKGKQAhpn-akTD-AM-Fppk--afdALGRLVASsaaKNKVDd 240
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
1JJI_A       232 ---pLASVIf--aDLENLPPALIITAEYDPLRDEGEVFGQMLRRAGVEASIVRYRGVLHGFI 288
gi 81841635  277 ---pFVSPLn--gAFRSLPPMTIFAGTRDLLYPDSVDLAERARAVGVPVELHLLRNQPHNYA 333
gi 81819342  223 ---aRISPLy--gTLKGLPPIYMYGGGREILSPDMHAFTHALEECGNDVEFKEYPKMVHDFP 279
gi 81855655  217 ---pEVSPLy--aDLSGFPPVFLQAGADETLVDESRMFAERARQAGVETRLDIFDDMLHSFQ 273
gi 81860439  237 ---pLVSPVfsdavLRQFPPTLLITATRAAELSNASYTHARLVDLGRESDLHVWDGLGHAFH 295
gi 81858402  270 ---pMLSPVyg--dVRDFPPTLLTTGTRDLFLSNTARMHLKLREAGVPADLIVFEGLSHAQY 326
gi 81817766  249 ---pLISPIyn--dLAGLPPTLLISGTRDLLLSDTARLQRKLRQNKVPVDLQLFEGLSHAEY 305
gi 81840019  192 ---pLASPVf--aDVTGLPPILVQIGENELMLSDAMRLATHLADNRVRVDLEVWPAMFHAWH 248
gi 81817126  219 ---sLVSPLf--gNFGDFPPVFVQCGEQELFHTDACALAQILEGAGVQVTLDVWPGMWHLFQ 275
gi 499210126 241 kpeeLYEPLd--hIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPGQVHVFQ 300
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