Conserved Protein Domain Family
Abhydrolase_3

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pfam07859: Abhydrolase_3 
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alpha/beta hydrolase fold
This catalytic domain is found in a very wide range of enzymes.
Statistics
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PSSM-Id: 311692
View PSSM: pfam07859
Aligned: 105 rows
Threshold Bit Score: 152.737
Threshold Setting Gi: 81841635
Created: 23-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3AIM_C        93 LVYYHGGGFV---LGDIESYDPLCRAITNSCQCVTISVDYRLAPENKFPAAVVDSFDALKWVYNNsekFNGKYG-IAVGG 168
gi 81860439   88 LIELHGGGFVmgsAASFGLMEAIPV--AAMTGITVVAVDYRMGPEHQFPAASEDVAAVYRAALKT-----YTPAqVGLFG 160
gi 81858402  124 LLHLHGGGYVl-gAGESGTLEAIFM--AGIGGYRIVSVNYRMPPDHPYLAAMDDALAVYRELLKT-----TPAQnIGVFG 195
gi 81817766  103 WVHLHGGGYAl-aGGELGTGEAVLA--AHYGQVGVISIDYRQPPNYPFPAALEDALVMWQELVKT-----HDVNrLALFG 174
gi 81817126   73 VLYAHGGFFI---SGSPMASRALCASLADEVGAKFYIPAYQLAPEHPFPAALENMYDAYVALIDQ---KKFRPEdIIFSG 146
gi 81845914   78 LFYIRGGGFC---FKTPNAHARLIADISARCQLDTFIPDYRLAPEHPFPAPCDDVLEAYLHLIEL-----KGDDnLILMG 149
gi 81841635  133 VMFLHGGGFI---NEIVPAHWRLIGQMTREARVVCVVPIYPLAPRVTAKDVVPATAELLRMLLED-----AGPAkVTVVG 204
gi 81855696   75 ILYLHGGAYV---FEITPYHWHLIADMADRLGYGITVPIYPIAPEHDFHAMFGMVGDVYRQMLDE-----TEAEdIVFMG 146
gi 81819342   78 ILYLHGGYNT---LQPSPFHWRLLDKLTLNTLHEVVLPIYPKSPDYHYLETFKAIRDVYNQLVEE-----VGANnIVMMG 149
gi 499210126  94 VLYLHGGAFL---GCGANSHRRLVETLSKLADSPILVVNYRLLPKHSIGMALDDCHDGYQWLRRL----GYDPEqIVLAG 166
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3AIM_C       169 DSAGGNLAAVTAILSKKEni-kLKYQVLIYPAVsfdlIT--KSL---YDNGEGFFLtre--hidWFGQQ---YLrS---F 234
gi 81860439  161 CSAGGVLTGEALAWFAKEqlpmPAAAGLFCAAGd--aRYrgDSQrvvAAVND-ALLpdvagtlpIMEDL---YY-Gp--D 231
gi 81858402  196 TSTGGGMTLALVLRARAEglplPAAIAPGTPWTd--lTKtgDSYftnEGV-D-NILvsydgwlgDAARL---YA-A---G 264
gi 81817766  175 TSAGGGLLLALVCQLRQLnlplPAAIAPLSPWVd--lTKtgDTHftnEYV-D-RTAisydglieGLARL---YA-G---E 243
gi 81817126  147 DGAGAGLMLALTHYLKQKglvcPRALALISPWVd--lTEdrFAGe-gVKKKE-LLLtrd--mfrYCALQ---YT-Y---A 213
gi 81845914  150 DSAGGNLALSLLLELKRLnlspPKACVLLSPALd--lAItgDTEl-iLAADD-PFFtl-----eSLLRLrgaYL-A---G 216
gi 81841635  205 NSAGAGLALAACQWLRDRghrqPNLMVLISPAAd--aSVsrPEQv-eIAARD-PMQdip--gilEAGRL---YA-G---E 271
gi 81855696  147 DSAGGNMAVVLTMMAAEEglplPARHVLISPGLd--mSLsnPKLf-eAERND-PWLgia--gglEAIRM---YS-A---G 213
gi 81819342  150 DGSGGGLALSFVQSLINDnqevPRKLFLLSPLLd--aTLtnPNItktLE-ENDILVsrf--gvhQLMKS---WT-N---D 217
gi 499210126 167 DSAGGYLALALAQRLQDVge-ePAALVAISPLLq--lAKkgKQAh-pNAKTD-AMFppk--afdALGRL---VA-SsaaK 235
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
3AIM_C       235 ADLLDF---RFSPIl--aDLNDLPPALIITAEHDPLRDQGEAYANKLLQSGVQVTSVEFNNVIHGFVS 297
gi 81860439  232 VDFRDP---LVSPVfsdavLRQFPPTLLITATRAAELSNASYTHARLVDLGRESDLHVWDGLGHAFHL 296
gi 81858402  265 HDLKDP---MLSPVyg--dVRDFPPTLLTTGTRDLFLSNTARMHLKLREAGVPADLIVFEGLSHAQYH 327
gi 81817766  244 LPLTHP---LISPIyn--dLAGLPPTLLISGTRDLLLSDTARLQRKLRQNKVPVDLQLFEGLSHAEYL 306
gi 81817126  214 DNFRNS---LVSPLf--gNFGDFPPVFVQCGEQELFHTDACALAQILEGAGVQVTLDVWPGMWHLFQS 276
gi 81845914  217 ANPMSE---RVSPLq--gNLAGLPPLLVIAGTRELLLQDSERLVMQVNACGGEVESRFYRNMPHVFPL 279
gi 81841635  272 LDVGHP---FVSPLn--gAFRSLPPMTIFAGTRDLLYPDSVDLAERARAVGVPVELHLLRNQPHNYAL 334
gi 81855696  214 IDRSDW---HISPIy--gDVSVLPTTLLLTGSHDLLTPDNLIFAQKARDAGVEVEVVHEEGMFHAWPL 276
gi 81819342  218 LPLSDA---RISPLy--gTLKGLPPIYMYGGGREILSPDMHAFTHALEECGNDVEFKEYPKMVHDFPi 280
gi 499210126 236 NKVDDKpeeLYEPLd--hIAPGLPRTLIHVSGSEVLLHDAQLAATKLAAVGVPAEIRVWPGQVHVFQa 301
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