2I1S


Conserved Protein Domain Family
PRiA4_ORF3

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pfam07929: PRiA4_ORF3 
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Plasmid pRiA4b ORF-3-like protein
Members of this family are similar to the protein product of ORF-3 found on plasmid pRiA4 in the bacterium Agrobacterium rhizogenes. This plasmid is responsible for tumorigenesis at wound sites of plants infected by this bacterium, but the ORF-3 product does not seem to be involved in the pathogenetic process. Other proteins found in this family are annotated as being putative TnpR resolvases, but no further evidence was found to back this. Moreover, another member of this family is described as a probable lexA repressor and in fact carries a LexA DNA binding domain (pfam01726), but no references were found to expand on this.
Statistics
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PSSM-Id: 336869
View PSSM: pfam07929
Aligned: 115 rows
Threshold Bit Score: 89.545
Threshold Setting Gi: 503453954
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A         7 KVYHLKLSIKGIT-P-QIWRRIQVPENYTFLDLHKAIQAVMDWEDYHLHEFEM----V-Npkt-gmlDK----------- 67
gi 81754142    7 TAFRFRVTLRLDG-R-ECWREILVPASLTFFDLHAVLQECFMWYGEHLFCFCAa-------------FP----------- 60
gi 552918039  57 QVLQFKIQLEFVKkP-PVWRRIQVPYEYTFFQFHLAIQCCMGWCNCHMHVFRAq---E-G-------FE----------- 113
gi 505429754 175 KAIKIKVKLDLEK-F-HIWRSAIVPLNYTFGEFHQVMQKLFDWKDYHLHDFLV----Y-Rgde-piiNI----------- 235
gi 504717090 176 EAVDIMVKLNLDR-H-TAWRRVITPVDITFKQLHIILQAVFGWKSYHLYDFEI----L-DeastcvlKV----------- 237
gi 504035797 180 psLQVSVTLELEH-E-NVFRRLIVPSCISFFQFHTILQEIFEWQNCHLHEFSL----GnN-------DK----------- 235
gi 505207044 176 eansLLVKLDLGG-Y-TAERRIVTPVDINFKKLHKILQIAFDWKDCHLHDFDIinekG-E-------RE----------- 234
gi 504366225 176 KAAVLKVELELGE-Y-QAWRKVIVPLNYTFRELHNILQQLYNWQDYHLHDFFI----Y-S-------KEkdatknwnhde 241
gi 503453954   2 gALKFRVLLDSEK-DqEIFRDIIINEDENFESFYRTILNSFNFEGQEIGSFFM----S-N-------DD----------- 57
gi 645065483 184 RAFELMVSLDLEV-Y-KAERKLIVPADLEFAQFHKVLQYVFNWNNYHLYDFAIidektknt------------------- 242
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A        68 --------------------IG---------Ae-------------------GDDF----DAFGGPLVSEKKAKLSDYFt 95
gi 81754142   61 --------------------NG---------KqvqveelwgeepsyheakyeQYMP----VEPLPEVRIASETELGDVF- 106
gi 552918039 114 --------------------IGnp------rMn-------------------EDFS----DLPQVRVQEEKTTLLRDYFh 144
gi 505429754 236 --------------------VG---------Se-------------------EDFE----YQMDTPMVMESKVKLSDYL- 262
gi 504717090 238 --------------------IS---------Ef------------------eEVYE----SSPDCPIRLDSEVNFSEYAk 266
gi 504035797 236 --------------------IT---------Md-------------------DFDDeiglYGDGIQIREESHVLLKDVF- 266
gi 505207044 235 --------------------LK---------Iise--------------yedEIDL----YNPGCKVVLESEAYIRDYIk 267
gi 504366225 242 yhkdgykailslamnqenfeYN---------Rd-------------------QLNF----AAEDFEQAVENEVKLKDVLp 289
gi 503453954  58 --------------------WDkgheislmdMs-------------------YSDE----DQELTSVMSES--KLTDFMe 92
gi 645065483 243 --------------------------------------------aarlvpteEDLE----YDESAVLMEGH--TLAEFF- 271
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2I1S_A        96 LENKEALYTYDFGDNWQVKVRLEK-ILPRkegVE--YPICTAGKRAAVPEDSGGVWGYEEMLEVLKDSE---HEEYEDTV 169
gi 81754142  107 PKARTARYYYDYGDDWIHDIKLLR-TYRS---VHvaDPQLWDGAGDAPPEDVGGVYGFERFLDTLGNPE---DEEHDGMV 179
gi 552918039 145 SREQKMIYEYDFGDSWEHIITYEG-TFDRkarTQ--YPKCLKGRGKCPPEDIGGYVGFKNFKEIMSDKN---HPEHEHFY 218
gi 505429754 263 PEYKSLKYRYDYGDNWEHIIKVEDaIFDYdknYS--Y--CLDGSGDKPPEDVGGEHGYEEFIEIMSNPI---HEEYEHMK 335
gi 504717090 267 QPN-KITYCYDYGDNWEHEITIRG-TNTey-nKT--YPVCLMGEGDAPPEDVGGIPGYVEFLKIMADPN---HVDYETMQ 338
gi 504035797 267 PEKKSCTYLYDFGDSWQHEIIFER-EITGst----lHATLLEMIGQAPPEDSGGPYGYEQNLACLKDRE---DPAYEETL 338
gi 505207044 268 DE-KIIKYSYDFGDGWEHEIIFEG-EIVdy-nRN--HPFCVDGFGDGAPEDVGGIPGYEEFLEIMGNAS---HPEYKSMK 339
gi 504366225 290 A---RIKYIYDYGDNWHHYLETVE-IIDdy-nKN--TPSFLEGEGTAPPEDVGG---FSEFMRIISNPD---DEEYESMV 356
gi 503453954  93 APDQKIILVYDFLRMWIFLIELQE-RIEEt--LD--KPKIALAVGIAPPEDS----------KIVQDDAffgDEEDEDMN 157
gi 645065483 272 PEHKQMLYTYDMGDNWEHIIQLVR-VIEE---YDgeLPYLLEARGKTPPEDVGGVGGFVSFRDIMLNPE---HPEYAEMK 344
                        250
                 ....*....|..
2I1S_A       170 LWLgd----dFD 177
gi 81754142  180 EWAed---qmWD 188
gi 552918039 219 DWYggkdfnpde 230
gi 505429754 336 QWAdsqdyggFD 347
gi 504717090 339 KWAqsqwyrnFD 350
gi 504035797 339 QWVtwrtgyryf 350
gi 505207044 340 IWAasqmyrkFD 351
gi 504366225 357 EWAesqrfeeyn 368
gi 503453954 158 EFDedf-gdgYD 168
gi 645065483 345 EWSr-----yWT 351
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