Conserved Protein Domain Family
DUF1682

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pfam07946: DUF1682 
Protein of unknown function (DUF1682)
The members of this family are all hypothetical eukaryotic proteins of unknown function. One member is described as being an adipocyte-specific protein, but no evidence of this was found.
Statistics
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PSSM-Id: 311755
View PSSM: pfam07946
Aligned: 167 rows
Threshold Bit Score: 147.305
Threshold Setting Gi: 156088967
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74632713   81 DWSKEAFIVAFIVFYVGLFYLGSSLNKKKINGWVDANKAVLASQFYQvganpVGV-------------------KD---R 138
gi 675860370 118 SFYMEILMLAGLGAYLLNYLAGKTKNQKLAQAWLKSHKQLLEENFSV-----IGD-------------------DGttmE 173
gi 156391215  63 gFYVEILTLAGLAAYALNFFAGRTKNSKLATAWLKSHKELLESNFHI-----VGD-------------------DG---Q 115
gi 115871278 139 SYYLELLMLAGVAAYLLNYMNGKSKNQRLATAWLNCHKELLEANFAL-----VGD-------------------DG---S 191
gi 358339929 187 SYYLEMLFVSMLVIYFSNFLVGRSKNTQLATAWFAAHKPILETQFAM-----VGD-------------------DGq-aE 241
gi 576694947 125 HYVFEMFFLAFIFLYLVNYMHGRATNSRLAAAWFAAHENLLSTNFSM-----VGD-------------------DT---S 177
gi 353233670 161 NFRLEILFVLALMIYTLNFLIGRSKNTQLANTWFSAHQPLLETNFAV-----VGD-------------------DGl-aE 215
gi 198415840 128 kYYVEILMALGIFVYLINFFIGKAKNNTLASSWLSHHLDFLHKSFAL-----VGD-------------------DP---Q 180
gi 674590128 122 kYTIEMILLAVILIYLVNYLHGRSVNSRIANLWYETHRDILTANFAL-----VGDnpnvvsvvednqesdsmneSK---S 193
gi 340375184 124 aYLVEICICLGIALYISNYLLGRTKNTNIAEGWMVHNLPILHSQFVL-----VGD-------------------DG---E 176
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74632713  139 -------K---I------------------LVADTPSNFTTYATGRINIDSLTAKAKLKTRQNLLTLMFEYV---FSFFM 187
gi 675860370 174 at----nT---G------------------LMKEAENIYSLWCSGRTCCEGMLVTIKMLKRQDLLSTISRMF---R---- 221
gi 156391215 116 ae----ePqqgI------------------MVKESESLYSLWCTGRTGCNGMLVELKLQKRHDLVNVMSYLV-------- 165
gi 115871278 192 ke----mP---Tsv---------------nLLKQSENRYCLWCSGRVFCEGMLVELKFLKRQDLLSVISRTM---H---- 242
gi 358339929 242 pg----sG---T------------------LLKESEHLYSLWCSGRAYCDAMLVELRLLKRQCLVFTLANW--------- 287
gi 576694947 178 at----pE---GnqeretsrggeksssnrrLIRESDSLYTLWCSGRVACTGMMVELRLMKRQDLPSLFLHWLhrpKSGVN 250
gi 353233670 216 pg----tG---T------------------LMKESEHLYSLWCTGSVHCDAMLIELRLVKRQCLFFAIANWI---R---- 263
gi 198415840 181 nkkiestN---E------------------LQKESEHVYTLWCSGRQCCEGMLVELKLLKRQDLISVIAH---------- 229
gi 674590128 194 ds----sL---G------------------LLRDSDSQYTLWCSGRVACQGMLIQIRLAPRQDLCLGLMHYL---ARPKT 245
gi 340375184 177 ge----ePtqnH------------------VVRRSENSFTVWASGRINCDGLLVHLELMKRHDLIHVILGLF---R---- 227
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74632713  188 DAVPVPTDEVTITLKInkNASVPDGIWAIVHKDAMRKAREDQYFL-S-L-----T---KTS---D---S-----DK---L 243
gi 675860370 222 ----PATDQIFVKVIMd-DSDMDNFVFCLSHKRSITKLQKDHADL-SnF-----C---PEKkscE---K-----FL---I 276
gi 156391215 166 ---KPVKDSITVTVHMt-DEEMDNFVFAIVPKKTVSKMQKELQDL-S-Ff----C---PDK---K---Sga--kYD---L 221
gi 115871278 243 ----PAGDEIKVTVTLd-ADSMDSFVLFFGAKKITNRMLKDMQDL-SqY-----C---GDKrggD---K-----FG---L 297
gi 358339929 288 --FQPAYDTIVAKVIMe-DSEMDGWVMAVGRKRRLQVLMKDHQDLaF-F-----C---PDK---RgqrH-----PG---L 344
gi 576694947 251 AATIASDDRVVVKVVLe-DGEMDTWVMAVGVKKSITMLAKDHFDL-A-------T---YPV---D---RrgqrfNG---V 309
gi 353233670 264 ----PVHDSIVVKVIMd-DSEMDGWVLAVGRKRRLQALAKDHQDLaV-Y-----C---PDK---RgqrH-----SY---L 318
gi 198415840 230 -QMKPINDQVTISVKMt---TLPSLVFCVGIKKSITNLHKTMQDL-C-LycadkA---KMG---E---K-----YN---L 286
gi 674590128 246 GPLSVSSDRLMIKVVLd-DGELDSWVFTVGVKKSLSVMVKDHFDLaT-Y-----P---QDR---K---G-----FKyagL 304
gi 340375184 228 ----PVPDTISFIFQCa-DGDMDSVITAICPRKTATKMSKEYEDL-SkY-----CsgiRSG---E---K-----HN---L 282
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74632713  244 PVSCVFMSEN-SELTEKLYNPALKELLTETAPYFRYLAITDLP--S--E-RPN---KA----Seye----ksL------- 299
gi 675860370 277 PSHFQMLSEC-SEVTAFILDSKVTAVLKKYEGAVEYLHFSDQYagV--K-QPEdstTT----Kvp------eT------- 335
gi 156391215 222 PASLVILSES-NEVANTLLTQQVTKAISNHEDMFESLLFSDQY--V--G-PKQ---ED----EdqaaakplkP------- 281
gi 115871278 298 PASTVVLAEL-GEVVNGVLDTKVLNCLNSHPEMFDYMHISDQF--S--GpKPA---AE----Deqpt-tmppT------- 357
gi 358339929 345 PESLTVLSEL-SEATTSMLNAPICKFLTDNEECVDYLFFSDQY--TgpK-PPP---DEtpsaKlp------vT------- 404
gi 576694947 310 PEGMIVLSEI-AEATATILNPTVLKVINDHQSAIEYIYISDQY--S--G-PKA---SM----Eel------kPpkp-eei 369
gi 353233670 319 PESFMLLCEI-PEVVPAIFNPLVCKFLNDFEESIEYLFFSDQY--S--G-PKP---PQ----Edt------tTptkppvt 379
gi 198415840 287 PLSMLMLSELyGDVPAFILDSTVVRVLKDHQNLFDSLHISDQY--Sg-A-KPL---DQ----Ndd------aPaip--et 347
gi 674590128 305 PEGMIVLSEI-PEVTSAILNPTVLKIFNDHPNIIEYIYISDQY--Cg-A-KPS---AE----Elk------pP------- 359
gi 340375184 283 PSSLSVISET-FDSAISVLSGGVAKFLSNHADMLLSLHVTDQY--T--G-LKE---EG----EesetvtikkG------- 342
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74632713  300 Vga--tKTVVLKLN-IP----S--GATd-------------------------LAKTAQLLETAINLVDTAtKLNLRPEV 345
gi 675860370 336 Q-----KVLIFCFN-VTdsgfT--SPKd-------------------------MDHMKPLLQMVFYCMDKIkRFRLSKEA 382
gi 156391215 282 K-----KVLIFNFT-VA----S--KGNtkv---------------------qdMARLESMMKLVLHCIDRVrKFRLGKEA 328
gi 115871278 358 E-----KVLICNFK-VP----GngSKSn-------------------------IEDMLPMMKMVIYLVDKIkRFRLSKEG 402
gi 358339929 405 Q-----KVLIFGFR-VG----T--KGSvsv---------------------edMETTAPLFQFIFYVIDKVhRLRLGKEA 451
gi 576694947 370 Q-----KVLIFSFI-L--------DEKd-------------------------VEAMKPLFNFVFYLTEKTrKLRLGKEA 410
gi 353233670 380 Q-----KALIFALRyVP----T--TTKsksfstsltssnnnangnlnqhhqqpIESATALFHFIFYVIEKVrRFRLSKEG 448
gi 198415840 348 V-----KQITLVIN-LP----E--KPSe-------------------------IGEMVPLLKMLIYLSDKLkKLRLSRDS 390
gi 674590128 360 KpnevqKVLICSFI-L--------KEDe-------------------------IENMKPLFNFVFYLLEKVrKVRLLKDA 405
gi 340375184 343 E-----KRIHLTFK-LP----Sd------------------------------LDQTTELLDFALKLLDHVkHIRLSREA 382
                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74632713  346 AKKIRATRETEIKKIQKVADEERAEEEAEKRAAAKKEADTKaISSLSPEAQRKAEQKLREKEARK 410
gi 675860370 383 KLKADKNRQKVLELYQKATHSQRSEAAQNRKEEKRRAEKEKiMNEDDPDKQRKLEEKNLKKEAKR 447
gi 156391215 329 RAKADKNRRELEENLLKQTHLQRQEAAQLRREEKRRADKERmMAEDDPDRQRRLEERVNKAEAKR 393
gi 115871278 403 KVKAEKIRAKVAESYVKLAHAQRQELAQQRREDKRRVEKDRlLNEEDPDKARRLEDKQYKKDMRK 467
gi 358339929 452 KAKSERNRQRAYDTRLKAVHSLRQEAAQTRREERVRANKERiMAEEDPEKARRLEEREQRkekak 516
gi 576694947 411 KAKSDRARTKVSETLLKSVQAARQEAAQNRRDEQRRAVKERiMTEEDPEKARRLEEREQKRENRK 475
gi 353233670 449 KAKSERNRQRAHDSHLKLMHSQRQEAAQNRRGERLRAAKERiMAEDDPEKARKLEEKEQRkeksk 513
gi 198415840 391 QIKADKHRADVADRYLKQTHAQRQEAAQQKKEEKARALKERmMNEEDPEKQRRLDEMIQRKEQnk 455
gi 674590128 406 KARADKARSKVYENAMKSVHQQRQEAAQNRRDEQRRAVKERiMAEEDPEKARRLEEKeqkkekkr 470
gi 340375184 383 KDKATKNRQLVVQEQEKLQHQQRQEAAQQRKEEKKKAEKEKmLEETDADKVRKWEEKEYKKQMKK 447
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