Conserved Protein Domain Family
DUF3294

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pfam07957: DUF3294 
Protein of unknown function (DUF3294)
This family was annotated as mitochondrial Ribosomal protein MRP8, based on the presumed similarity of the S.cerevisiae protein to an E.coli mitochondrial ribosomal protein; however, this similarity is spurious, and the function is not known [Wood, V].
Statistics
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PSSM-Id: 311763
View PSSM: pfam07957
Aligned: 25 rows
Threshold Bit Score: 237.179
Threshold Setting Gi: 575519929
Created: 20-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74605786    1 MSD----EISKLRNQVLELQGLVKRQSTMLAKTGQSVIELQIAQQKTDIRSLDLEKkpnk--paaAEASL--SIDTSEFA 72
gi 74602378    1 MADkkdlTLEQLHDQVQSLSKVVEMQSQLIAKTGKQLMDIQVKDVKSKMNADTEKS---------SSKVA--NVDMDDYA 69
gi 74586061    1 MSEl--sKLNEAKAKVAELEALVKKQASVMVQARQKLVDVELRNKKNQAAQN-------------INQQP--ALDLTDYV 63
gi 74634649    1 MPEp---TIESLKKEVDFLSAQLRKVTGLVAETGKQVLSIQVNQEKGALNNLTITDvegkpvqsqKDKAS--SSEDSQAV 75
gi 403217155   1 MSS----ELEELRKQVTQLEQLVAKQTKVLSKTGQSVLELQVSNQKRDVDNFGPPTa--------SKTVArdKFDSTEFA 68
gi 255729424   1 -mS----TSEDVNQRISALEALVEKQSKLIAQTGQRLMEMQIKNLKGQLDSST------------TTNQP--PVDMSDYI 61
gi 754419130  10 kvP----TVEELTNQVNDLTLLVKKQSQLLSKTGEQVLSLQVKSQKESIDNFDPKSlrgs-ssrvSKKIP--QLDTTDFA 82
gi 927374719   1 MSS-----LEELKNEIDELKELVARQSKVISRTGEQLLRFQVRQTDRELNSIDVPRvgp---dgtISKQG--QIDTSEFA 70
gi 598064409   1 MPEl---TLEQLNEQVAKLSGLVERQSKIIAETGEQVLQLQVKDVKTRMSALDM-----------KPQQP--EIDLTDYI 64
gi 354544517   1 -mS----NIEDINKKIQELEGLIEKQSKVIATTGQKLLEIQVKDVKSRMTELDSG----------SNKPH--SFDAADYV 63
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74605786   73 TNGDLEQLVEELQGQLDYLEERSIRRVANNNKRDPAD--AIGPLPNADGDLPIDLk-------iPLPETVQEFSNIKDLD 143
gi 74602378   70 TNEDIIQLVGELQGQLDMLEDRNIRRTINSHLGIDDEdgLIIPIPNKDGDEPPYD---------FCPANIDELVKLNKYE 140
gi 74586061   64 NNDDIVQLVTELQTQLDALEARTMRRTYNATVQGDDE--KLAPITNKDGDLPDFA----------LPVTLKEFKSLEKID 131
gi 74634649   76 TSEDLVVLVTELQDQLDNLETKSIRRTANSFAQKDAD--LIASLPRIDGMCPAQElddethpdwVFPKTLGEFKKLDNAK 153
gi 403217155  69 TNDDIIGLVGELQIELNHIEERSIRRLVNATKTEEKD--ILAPLPNADGDTPDFKt-------sFFPKTMKEFIEIDDVN 139
gi 255729424  62 TNEDIVQLVTELQTQLDSLEDRTMRRVYNSTLQYDEE--TLAPIMNRDGELPEFA----------VPKTLQEFKDLSKKE 129
gi 754419130  83 TNEDLVELVGELQGQLDVIEERSIRRLVNSHK-KSTD--ILAPQLNHDGEEPPLE---------IYPKNVEEFTKISDSN 150
gi 927374719  71 TNDDLVQLVGELQGQLNILEQRSLRRTINSGLSKDTD--LIAPVLNSDGDEPPET---------LYPKTLKEFRDLSDDS 139
gi 598064409  65 NNEDIVQLVTELQTQLDNLEDRTIRRCSNASITKPSD--FLAPLTNRDGDLPDFE----------LPNTLQEFQNLDKVD 132
gi 354544517  64 GNDDIVQLVTELQSQLDNLEDRATRRTYNSTLTKDEQ--KLAPLSNKDGDEPQFT----------LPSTLKEFKDMTKDK 131
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74605786  144 LCKVAEFYGVLPfP------Q---------SDLEAITE--GlrNEEDVSIP--T------FTDATAADQLKKYTKEEMDV 198
gi 74602378  141 IVQLCEFYELVI-Pmd---qQ---------EHLKRFLQ--NnnEMVDMEGA--KrllevgADNATLMERVDAYSEKQIDE 203
gi 74586061  132 LIRLGVFYEIIL-Pd----gE---------EIDHALQQ--T--NSKEAILD--I------NKKKDIIELSKNFDEDQANE 185
gi 74634649  154 VEQWMRFYELLP-Pde--aeLaklqevlgkEELEEAME--N-------------------------ARKSAELSEAEAIE 203
gi 403217155 140 LFKLARFYECLP-Ptm--keQ---------DDLEKFLD--G--KLDNLHVN--D------FDDATIKKELENYKKDQLDD 195
gi 255729424 130 LIRLGVFYEIIV-Pn----eQ---------EVEQALEQ--D--NAKDAILD--I------SKNKDIEEMSKSFDDDQVNE 183
gi 754419130 151 LVQLARFYEALP-Pte--aeK---------REFEAFVE--G--KSDKVQ-------------ESSIKVDASSYSKDDLDE 201
gi 927374719 140 VLSLCHFYELLP-Ptl--eeE---------AKLRAFME--G--KIKS---P--N------VDPSEFKPSSADYSKEVLDG 192
gi 598064409 133 IIRLAVFYEIII-PnqgselE---------QQPEGVVP--GisHAPAAGATavE------NNSVDIIELSKQFDEIQAIE 194
gi 354544517 132 VLELGIFYEIIL-Pn----eE---------EINEVLERdtG--NSKNDIIN--L------AKNKDISKLEDQFSDEQVDE 187
                        250       260
                 ....*....|....*....|
gi 74605786  199 IFDTVARYLGLNNRRTKGTW 218
gi 74602378  204 LFDLLTRFIGVRVIRGNYAW 223
gi 74586061  186 IYDELARYFGIKHRRNSDGW 205
gi 74634649  204 RFDTLARFFGLRERRGTNAW 223
gi 403217155 196 IFNEVARYIGLRSRRGDDIW 215
gi 255729424 184 IYDELARYFGIKHKRNSDGW 203
gi 754419130 202 AFDKVARLLGLPVRRTVEAW 221
gi 927374719 193 LYDDLARFLGLKFRKTEHAW 212
gi 598064409 195 IFDELARYLGIKYRKGSNKW 214
gi 354544517 188 VYDELARYFGIRHRKVSDGW 207
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