2QK7,3ROH,4P1X,4P1X,4Q7G,4YHD,4TW1,1XEZ,5K59


Conserved Protein Domain Family
Leukocidin

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pfam07968: Leukocidin 
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Leukocidin/Hemolysin toxin family
Statistics
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PSSM-Id: 336883
View PSSM: pfam07968
Aligned: 24 rows
Threshold Bit Score: 236.872
Threshold Setting Gi: 1052245134
Created: 20-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2QK7_A        37 QNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKkypy------ikrMIWPF----------------------QYNI 88
gi 81755472   71 RSVQSATSDGFTPDAKIVRFTVDADKPGTGIHLVNElqqd-----hswfQSWANrrtyi------------gpfasSYDL 133
gi 134048491 222 RSLQFGNTGSATPDAKIVRISLDEESAGAGIQLNED-------------LTWSEniadyllldgwardyatdaiaqDYRF 288
gi 81434015   62 NSIKVSFIEDPYADKKIAIVTTDGSNIDAKYTINSGyyn--------agLKWPS----------------------AYHT 111
gi 81435579   64 mSLKVTFIDDPSADKQIAVINTTGSFLKANPTISDApidnypipgasatLRYPS----------------------QYDV 121
gi 122540475  62 kkVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEgan-------ksgLAWPS----------------------AFKV 112
gi 122538736  60 QILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNdyd-------fskLYWGA----------------------KYNV 110
gi 12644111  215 RSLQYGIVGSATPDAKIVRISLDDDSTGAGIHLNDQ-------------LGYRQfgasyttldayfrewstdaiaqDYRF 281
4P1X_A        44 QILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNdyd-------fskLYWGA----------------------KYNV 94
4YHD_A        37 kkVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEgan-------ksgLAWPS----------------------AFKV 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2QK7_A        89 SLKTk-DSNVDLINYLPK-NKIDSADVSQKLGYNIG--GNF-----QSAPSIGG--SGSF--NYSKTISYNQKNYVTEVE 155
gi 81755472  134 WVKPvsGYTPKKARDLPQ-NENKNYQHRDTYGYSIGinGKVgaevnKDGPKVGGevSGSFtyNYSKTLVFDTKDYRINNR 212
gi 134048491 289 SIEAs-NTKAAVLKSLPT-NLNSKYEHREISGFEVGvtGGVev--nKDGPKAKLeaSAKF--SQQRQLAYNTQDYRVERS 362
gi 81434015  112 EAEItsGDSAQFHKAAPV-NTMTSAKVTSEVGYTLG--GSVkvgvnDKGPNADAsiTGSF--AWKESVSYDQVDYKTVLE 186
gi 81435579  122 AFNLq-DNSARFFNVAPT-NAVEETTVTSSVSYQLG--GSVkasvtPNGPSGEAgaTGQV--TWSDSVSYKQTSYKTNLI 195
gi 122540475 113 QLQLpdNEVAQISDYYPR-NSIDTKEYMSTLTYGFN--GNVt---gDDTGKIGGliGANV--SIGHTLKYVQPDFKTILE 184
gi 122538736 111 SISSqsNDSVNVVDYAPK-NQNEEFQVQNTLGYTFG--GDI-----SISNGLSGglNGNT--AFSETINYKQESYRTTLS 180
gi 12644111  282 VFNAs-NNKAQILKTFPVdNINEKFERKEVSGFELGvtGGVev--sGDGPKAKLeaRASY--TQSRWLTYNTQDYRIERN 356
4P1X_A        95 SISSqsNDSVNVVDYAPK-NQNEEFQVQNTLGYTFG--GDI-----SISNGLSGglNGNT--AFSETINYKQESYRTTLS 164
4YHD_A        88 QLQLpdNEVAQISDYYPR-NSIDTKEYMSTLTYGFN--GNVt---gDDTGKIGGliGANV--SIGHTLKYVQPDFKTILE 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2QK7_A       156 SQNS-K-GVKWGVKA---NSFVTPNgqvsayd----------qylfaqdP-TGPAARDYFVPDNQLPPLIQSGFNPSFIT 219
gi 81755472  213 SSLS-DfDISFEREFgecDELRRQElgc-------------------yfT-AAHWGSGWVFDKTKFNPISYSNFKPNYDV 271
gi 134048491 363 APSA-Q-KVSFSWVR---DQYATAEsll------------------sskT-ATVWGMGYDVDHNRIQPLSYKGFVPNLDV 418
gi 81434015  187 THTD-K-KLNWKVGF---QSFNFPEwgiynrdsfntf----ygnqlfmksrsyNEGTNNFVSKDTVPALTGYGFSPNVVA 257
gi 81435579  196 DQTN-K-NVKWNVFF---NGYNNQNwgiytrdsyhslygnqlfmysrtyL-YESDAKGNLIPMDQLPALTNSGFSPGMIA 269
gi 122540475 185 SPTD-K-KVGWKVIF---NNMVNQNwgpydrdswnpv---ygnqlfmktrngSMKAADNFLDPNKASSLLSSGFSPDFAT 256
gi 122538736 181 RNTN-YkNVGWGVEA---HKIMNNGwgpygrdsfhpt---ygnelflagrqsSAYAGQNFIAQHQMPLLSRSNFNPEFLS 253
gi 12644111  357 AKNA-Q-AVSFTWNR---QQYATAEsll------------------nrsT-DALWVNTYPVDVNRISPLSYASFVPKMDV 412
4P1X_A       165 RNTNyK-NVGWGVEA---HKIMNNGwgpygrdsfhp---tygnelflagRqSSAYAGQNFIAQHQMPLLSRSNFNPEFLS 237
4YHD_A       160 SPTD-K-KVGWKVIF---NNMVNQNwgpydrdswnp---vygnqlfmktRnGSMKAAENFLDPNKASSLLSSGFSPDFAT 231
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
2QK7_A       220 TLSHE-KGKGDKSEFEITYGRNMDA-TYA-----YVTRHRLAVDRKHDaf---knRNVTVKYEVNWKT 277
gi 81755472  272 LYEAP-VSETGVTDFEMGVKLNYRArFGTvlpsaLFSVYGSAGSSTNS-------STVKQRIRIDWNH 331
gi 134048491 419 IYKAA-PDETGSTEFKIDSSVNIRP-IYTgiykhYYVVGAHVSFQGFEdtdkrrrVTASTSFKVDWNH 484
gi 81434015  258 VITAD-K-TETTSDLKITNRRISDQ-YNI-----EWVSSKWWGTNNKDty----nEFFTNHYKLDWKN 313
gi 81435579  270 VVISE-K-NTDQSNLQVAYTKHADD-YQLrp-gfTFGTANWVGNNVKDvd----qKTFNKLFTLDWKN 329
gi 122540475 257 VITMDrKASKQQTNIDVIYERVRDD-YQL-----HWTSTNWKGTNTKDkw----iDRSSERYKIDWEk 314
gi 122538736 254 VLSHR-QDGAKKSKITVTYQREMDL-YQI-----RWNGFYWAGANYKNfk----tRTFKSTYEIDWEN 310
gi 12644111  413 IYKAS-ATETGSTDFIIDSSVNIRP-IYNgaykhYYVVGAHQSYHGFEdtp-rrrITKSASFTVDWDH 477
4P1X_A       238 VLSHR-QDGAKKSKITVTYQREMDL-YQIr-----WNGFYWAGANYKNfk----tRTFKSTYEIDWEN 294
4YHD_A       232 VITMDrKASKQQTNIDVIYERVRDD-YQL-----HWTSTNWKGTNTKDkw----tDRSSERYKIDWEk 289
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