Conserved Protein Domain Family
GSDH

?
pfam07995: GSDH 
Click on image for an interactive view with Cn3D
Glucose / Sorbosone dehydrogenase
Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.
Statistics
?
PSSM-Id: 311795
View PSSM: pfam07995
Aligned: 96 rows
Threshold Bit Score: 263.252
Threshold Setting Gi: 123380600
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2ISM_A        30 LEVP---WAL------AFLpD-G-GM-LIAER-PGRIRLFR-EGRL--STYAEL----------SV----------YHRG 73
gi 123380600  78 DQYPtgpFEMlgnkhfLFItKcG-EVyFTRINeSGEIEITKnADSLtkPGLDEReeskgddydgLV----------YCKE 146
gi 123516805  82 LNVP---WSL------VFLpD-K-RA-LVSER-SGKIRLII-NGKLesHPYATV----------DA----------VRIG 127
gi 74517189   96 LEIP---WDL------SFAaD-G-TL-FLTER-VGRVLSFV-DGSV--RTVTEPa--------aVIdaessddgwwVTGG 151
gi 122980669  59 LETP---WGI------AWLp--GgDA-LVTER-PGRIRLLK-DGVLqpRPVATVp----------V----------ADAA 104
gi 123480831  65 LDHP---WDA------VQApD-G-AV-LTGQR-SGGFFVRRaNGST--GPVTADl--------sDL----------YAQS 111
gi 908630289  62 LDHP---WDV------RPIgD-G-RL-IFTQRdRATVSIWD-GSRT--RLVQGFp--------sDSv---------WVSG 109
gi 160339180  47 LKIP---WGI------DFAqD-G-RI-FFTER-PGTVNVIE-DGQV--SQIMSR----------GV-----------GGG 89
gi 118195710  76 LDEP---RHL------AFYgD---RV-FLTEK-AGRVRVVQ-DDVLleEPLAVL----------RV----------ADEL 120
gi 160340370  49 LEKP---RSI------AVS-D-N-RI-FVTEK-DGSIVVIE-NDIQleSPLATF----------RS----------ANVF 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2ISM_A        74 ESGLLGLALHPRFPQEPYVYAYRTv---aEGGLRN-QVVRLRHLGE-----RGVLDRVVLDGIPA-RPH--GLHSGGR-I 140
gi 123380600 147 LAGVKDSLLVGN-----TLYVVYTtwdheANGARL-AVSAFELDQEq---sELTFSKDIFLTYPAvKEPflGHQVGGK-L 216
gi 123516805 128 EAGLMGLAMHPRFPAEPYIYAMYTeq--kKGALRN-RVVRFRDhg-----rTGSFDRVILDDIPG---G--RFHDGGR-I 193
gi 74517189  152 EGGTLGVAAHPTYPDPPVVYVYYTt-----mTDDDeRVNRVVAMDVsaedpAAT-ESVLVDNIPG---S--KIHNGGR-L 219
gi 122980669 105 EGGLLGIAAHPNFANNRQFYIYVTtd--aGGTEEN-RIERWTLSEDh---tTATHERVIFGGIAS---A--KYHDGGR-L 172
gi 123480831 112 ETGLMGIALASNFANTRTLYTCQGf---qGGGVTDiRIQSWTVDAGw---tTLTRGSAILTGIPV--NE--GRHGGCR-I 180
gi 908630289 110 ETGLMGLEVDPSFASNRTFYTCQGgf-taGGGHDV-RIIRWTLRDDl---vSISGSKRLLGGLPA--TS--GRHGGCRlL 180
gi 160339180  90 EGGMLGIALDPEFEKNHYVYVYYTyn--eLLGIKN-RLVQYVESDN-----KLNHEKILLEDIPG---A--PYHDGGR-I 155
gi 118195710 121 DSGLLGIAVHPDFGENHKLYVYHSyi--eDGAAWN-RILQITERDN-----KLEDAETVLDKIPG---S--RFSNGGV-I 186
gi 160340370  94 DGGLLGIDLHPNFAENHYLYVFLTye--eDEALWN-KILRITESEN-----KLQDAETIFDKIPG---S--SFTNGGF-I 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2ISM_A       141 AFGpDG-MLYVTTGEVYE-RELAQDLASLGGKILRLT-PEGEPAPGNPFLgr-rgARPEVYSLGHRNPQ-GLAWHPKTGE 215
gi 123380600 217 VLGaDDdTMFLSVGDFSK-PDGVQDPSTALGKMIKINlKDASA---------------EIYASGLRSPSgGLYFDRDSNE 280
gi 123516805 194 AFGpDG-MLYVTTGENFN-ADLAQDRSSLAGKILRIS-PDGEIPADNPF------KDSPVYSYGHRNPQ-GLAWQPETGR 263
gi 74517189  220 TFGpEN-YLWITTGDAGD-GELSADTDSLGGKVLRVT-PAGDPAPGNPELg----GDPRVFTYGHRNPQ-GLAWLPD-GT 290
gi 122980669 173 RFGsDG-MLYAGTGDARD-PDRSQNANDPAGKLLRLT-PEGAVPQDNPI------PGSPAFLTGIRNLQ-AFDWR-DAST 241
gi 123480831 181 LTAaDG-TLFIGTGDTAQ-PTVSQDPNSLGGKTLHIN-TDGTPAAGNPD------PASPVYTLGHRNAQ-GLAQQPGTGR 250
gi 908630289 181 AVGk---RLYAGTGDAAT-GSTPENKKSLGGKTLCLLaATGKPCGSNPFAgsknhNKRYVHTYGHRNVQ-GLDRRRD-GT 254
gi 160339180 156 KFGpDE-MLYVTTGDAVE-PELSQNLNSVAGKILRIK-SDGTIPEDNPF------GSA-IYSIGHRNPQ-GIAWD-KSGN 223
gi 118195710 187 KFGpDG-KLYVGTGSVSDtLHLSQEMDSLGGKILRIN-DDGSIPSDNPF------EGSPVYSLGHRDPQ-GMAWSSD-GT 256
gi 160340370 160 KFGpDG-KLYVGTGATSDsSHLPQDLDSLSGKILRIN-DDGSIPDDNPF------SNSPVYSLGHRNPQ-GMTWDNN-GN 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2ISM_A       216 LFSSEHGPSGEqgy-ghDEVNLIVPGGNYGWPRVV----------GR--------GNDPR-YRDPLY-FWPQG---FPPG 271
gi 123380600 281 LWETEHGPKGG------DEINLIKQGRNYGWPLVSygtlyeregmGNyyg--nkyNSHED-FEKPAF-VFNPS---IGVG 347
gi 123516805 264 LFESEHGPSGEfahfghDEINRIVKGGNYGWPLVI----------GA--------PEIQP-YIDPLI-VWKEA---TPPG 320
gi 74517189  291 LVASEHGPTGR------DELNRLEAGGYYGWPDTRkha--------------eylDADPE-VRRPLAnTGNTGg--WAPS 347
gi 122980669 242 LYIADHGPSGEtlrrghDEVSVARRGDNLGWPGIY----------SC--------ETREG-QITPSI-TYKDA---MPPG 298
gi 123480831 251 IYAVDQGTTRD------DEVNLLVAGGNYGYKPDRipg----iydESvp------mTDPSrVPGAVAaAWSSGsttLATG 314
gi 908630289 255 LWSVEQGSYRD------DEVNRLRKGGDYGWNPVP----------GYdesvpmtdQSLPGrQRAA---VWRSGdptLATS 315
gi 160339180 224 LIATEHGPSGWrgv-ahDEINWIVSGANYGWPDVI----------GD--------ETLEG-ATNPILhSGDDT---WAPS 280
gi 118195710 257 MYASDLGPSKN------DEINVIIPGGNYGWPDHE--------------------CSGGG-YEDSIL-CFDPA---IEPG 305
gi 160340370 230 LYVSEFGPEKN------DEINIILAGKNYGWPEQEc-------------------SGNES-FENAVL-CYDPS---IEPG 279
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2ISM_A       272 NLAFF---------RGDLYVAGLRGQALLRLVL-EgErgr----------------wrVLRVETAL------SGFG-RLR 318
gi 123380600 348 AIAKYpktgkneywEGGFFVAGMAANSLLYMR--KeGe-------------------rLVYAEPVL--------HDyRIR 398
gi 123516805 321 GIAFYngtf-lphlKGDLFVATLKSRALIRVRF-DgDt-------------------kISRIERWFstdfkkGKYG-RLR 378
gi 74517189  348 GSLFYtgda-vpslRNRLLTGGLNGQTLLVTTLtPaGadlppgadaevydadwtddayTATTHSLLa-----NEIG-RIR 420
gi 122980669 299 GAAIYtgta-ipewKGSLLIGTLGSRHLQRVEF-ApDss------------------rVTRHEVYLr-----NTYG-RLR 352
gi 123480831 315 SAAFVtgpg-wgpwDGALVMGGLKTKQLIFLRLaAdGq-------------------sVTAQTFGLq-----NQYG-RLR 368
gi 908630289 316 GGGFVygkr-wgalDGSFAVAALKAERVLFLQL-SaSgr-----------------lqRVRVPAALr------QHG-RIR 369
gi 160339180 281 GSTFYygdd-mpmfDGKYFVAALKGQHIHVIEF-DeSy-------------------nVLFHGELFs-----GEFG-RIR 333
gi 118195710 306 GLVVYsgeq--lefGGSLIMTSLRVGSLYGFDPtDgG---------------------LEDRQSIL------AGLG-RIR 355
gi 160340370 280 GILYYtgdk--fdfEFPFIMASMRASNVYQVDF-DeG---------------------LSSQKSIL------SGIG-RVR 328
                        410       420
                 ....*....|....*....|...
2ISM_A       319 EVQVGPDGALYVTTSnrDG---R 338
gi 123380600 399 ALKIDKNGRFFIKTDn-DQflwm 420
gi 123516805 379 DVVTGPDGAIYFTSSnrDG---R 398
gi 74517189  421 HVEQGPDGGLYLVTSnrDGragD 443
gi 122980669 353 EVIMGPDGHLYVTTSncDG---R 372
gi 123480831 369 SVTPTADGSLLVTTD--NGstdQ 389
gi 908630289 370 TVVDGPGSVAYVTTDngNG---N 389
gi 160339180 334 DVANGPDG-LYFMTSnqDG---R 352
gi 118195710 356 DVDEGPDGYLYALTSntDG---R 375
gi 160340370 329 DVVQGPDGYLYVITSntDG---K 348
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap