Conserved Protein Domain Family
PDDEXK_9

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pfam08011: PDDEXK_9 
PD-(D/E)XK nuclease superfamily
This family contains many hypothetical bacterial proteins. It has been identified as a member of the PD-(D/E)XK nuclease superfamily through transitive meta profile searches. DUF1703 has the predicted secondary structure pattern of the restriction endonuclease-like fold core and contains an additional beta-strand at the C-terminus.
Statistics
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PSSM-Id: 311804
View PSSM: pfam08011
Aligned: 41 rows
Threshold Bit Score: 77.6785
Threshold Setting Gi: 501003615
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121723896 455 VNENFYRTTFYELCSrylSNWFIWNIERSYPQGRSDLEFVgky-herFANLRWVIEFKyfsNTEFSKMKCKiediplkeE 533
gi 81485474  464 KGEKVYHSLFLGMLIw-lRDKYEVKSNGERGHGRYDAMLIpl----dKVRPAYVFEFKvskTIKALNAKAE--------E 530
gi 121721513 456 LPEAVFHAFVLGLLAn-lISVYDVRSNAESGLGRADILMIpk---ttRYQTGYVIEFKsiyPNDDIEKSAQ--------E 523
gi 121697678 449 LPEAVFHAFVLGLLAn-lRTVYEIRSNAEAGFGRADILMIpk---trDYPTAYVIEFKttdGQQNTEIVS---------D 515
gi 81485159  113 GNEAFYHGLIMGMGLy-lEGEYITKSNIESGLGRYDFLIEpk----nKSKRAFIMEFKstdSVEKLEEISK--------E 179
gi 81443300  462 EGEHNLQGFFKAYLAl--ASYYLVQPELEMNYGYCDFFLLpdksrypDTAHSYILELKylpRTATDKELEEqa-----eE 534
gi 81442882  463 EGERNIQGFFTAYLSv--NAYYLTAPEVELNHGYCDLFLMpdl-lhyEVNHSYIIELKylsEKDSDAKAEIqw-----eE 534
gi 81442667  450 EGERNIQGFFTAYLSv--NAYYLTTPEVELNHGFCDMFLMpdlqryaEIAHSYIVELKylpKEKFDAQSAEqw-----eE 522
gi 81444026  469 EGEAHIKGFLLAYLGm--YRYYQLYPEYELNKGFADFLFKpspsvpvMPPLTYLLEVKyakAGASEKEIRAla-----dG 541
gi 81443443  466 EGEAYVKTFILAYLGl--THYYIARPEYESNKGYADIFLQprllqlpDMVYSYCIEVKyakRDASDTEIEKll-----sN 538
                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 121723896 534 DTRQIQGYAQGLMQEYPE---ASIRLFVIYCIGNQGFRVFE 571
gi 81485474  531 ALEQIKEKQYDVGLKDLGi--TKIYRIGIAFKGKNVKVKYE 569
gi 121721513 524 ALTQIRERKYDSSFISGGiepNIIRYLAVVVQGKSVMVKEW 564
gi 121697678 516 ALNQIRNQEYEAALSNAGisdEQIVRLAIILQGKEVRVATG 556
gi 81485159  180 ALKQIEDKKYDISLKQNGi--KEITHIGIAFYGKQIKIKHK 218
gi 81443300  535 GRGQLKQYSRDKKVTTISe-gTALHCILLQFKGWELIKCEE 574
gi 81442882  535 AVEQIKGYAAAPKVRQLIq-nTKLHCIVMQFRGWELQRMEE 574
gi 81442667  523 AVAQIHGYAASPKVRLLCq-gTQLHCIVIQFCGWEMVRMEE 562
gi 81444026  542 AREQLLRYSQDELVTEARa-kGGLKLITIVWCSWELVLLEE 581
gi 81443443  539 AKIQLKQYAASEWIHQDKg-tTELKSIALVFQGWKLVRVEE 578
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