4UD8


Conserved Protein Domain Family
BBE

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pfam08031: BBE 
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Berberine and berberine like
This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.
Statistics
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PSSM-Id: 336907
View PSSM: pfam08031
Aligned: 45 rows
Threshold Bit Score: 54.4913
Threshold Setting Gi: 81709687
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
4UD8_A         475 AYVNYRDLDLGtnegetdarEWGAKYYK-GN-FERLVKIKGEFDPDNFFRHEQSVP 528
gi 81576655    524 SYVNEGNFFEP---------NWKQEFWG-PN-YERLLGIKRRYDPTNLFRVHHGVG 568
gi 1160578037  412 SYRNLGDPQEK---------EFQARYWGaDN-YARLAATKAAWDPSHLFMTSLGVg 457
gi 74628921    597 GYLNEGDVMEP---------EFGEAYFG-SN-YERLSQIKKAVDPTGLLWAPTAVG 641
gi 74628313    419 TYAGYVDPELK---------DAPQQYWG-SN-YEELRRVKKVWDPKEVFWNPQSVR 463
gi 74628551    453 mYINYADPTMKr-------aEAVGNYYR-SS-LSRLQKVKAQYDPNEVFYYPQSVE 499
gi 81592480    458 CYINYPDVDMLay------pFWPQLYYGdGDlYAFLQRVKRRYDPNNIFHHAMSVR 507
gi 81538831    495 CYINYADADLAdpalnrsgiPWHELYFK-GN-YPRLQRVKATWDPRNVFSHRLGIR 548
gi 85102097    507 AYMNEGNFQQP---------DFQHQFFG-SN-YNNLLCIKKKYDPTNLFYATAAvg 551
gi 992230609  1060 AYLNEADFRQP---------NWQKYFYG-DN-YATLRKIKAKYDPDNLFYATTAVg 1104
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