Conserved Protein Domain Family
BBE

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pfam08031: BBE 
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Berberine and berberine like
This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine.
Statistics
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PSSM-Id: 311815
View PSSM: pfam08031
Aligned: 46 rows
Threshold Bit Score: 54.4922
Threshold Setting Gi: 81709687
Created: 21-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
4UD8_B        475 AYVNYRDLDLGtnegetdarEWGAKYYK-GN-FERLVKIKGEFDPDNFFRHEQSVP 528
gi 74628551   453 mYINYADPTMKr-------aEAVGNYYR-SS-LSRLQKVKAQYDPNEVFYYPQSVE 499
gi 81592480   458 CYINYPDVDMLay------pFWPQLYYGdGDlYAFLQRVKRRYDPNNIFHHAMSVR 507
gi 81538831   495 CYINYADADLAdpalnrsgiPWHELYFK-GN-YPRLQRVKATWDPRNVFSHRLGIR 548
gi 74629168   453 VYVNYAHGDET-----------PEQMYG-RNkLHRLAKLKKQYDPSSVFGFHNPLP 496
gi 81576655   524 SYVNEGNFFEP---------NWKQEFWG-PN-YERLLGIKRRYDPTNLFRVHHGVG 568
gi 74628921   597 GYLNEGDVMEP---------EFGEAYFG-SN-YERLSQIKKAVDPTGLLWAPTAVG 641
gi 992230609 1060 AYLNEADFRQP---------NWQKYFYG-DN-YATLRKIKAKYDPDNLFYATTAVG 1104
gi 85102097   507 AYMNEGNFQQP---------DFQHQFFG-SN-YNNLLCIKKKYDPTNLFYATAAvg 551
gi 399168943  412 SYRNLGDPQEK---------EFQARYWGaDN-YARLAATKAAWDPSHLFMTSLGVg 457
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