Conserved Protein Domain Family
UME

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pfam08064: UME 
UME (NUC010) domain
This domain is characteristic of UVSB PI-3 kinase, MEI-41 and ESR1.
Statistics
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PSSM-Id: 311831
View PSSM: pfam08064
Aligned: 131 rows
Threshold Bit Score: 51.7314
Threshold Setting Gi: 953473835
Created: 26-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75252859  1115 FLKNDFVRLLNSIDKKM--LHSS-DVNLQKQALQRIRKLVEMMGPYLSTHAPKIM-----------------VLLIFAID 1174
gi 336373879  477 FLKDHMLGIISDMNDTLqdVLGKkSISEKRQILRSIGALIGHIGPAINSVSPQIM-----------------AMLQTMFL 539
gi 449549539  473 FLRSYMLGVITHINDMLqdVQGKrPIEAKKRIIKSLGPFMTEVGPGVSHVAPQIM-----------------ATLQTMLP 535
gi 215472508  132 FLKSYILGLITTINDMLqdVHGKkSIETKRMIIRSLGVLVEEVGPGISSVAPQIM-----------------ATFQTMAC 194
gi 568442725  466 FLKVHMLGLMSYINEMLqdMQGKkSVASKRKIIKGLGELIVQIGPNISYGAPQVM-----------------ATFQTMVN 528
gi 443917690  876 FLTNHLLGIVMHINDALqdVRGKaTVSQKIQMIKSLGVVVKSVGASSSLVSPQIM-----------------ATLQSMIR 938
gi 527297949  481 FLSPHVLGIIAGINDQLq--FSKrTVESKRAIIRSIGGFAREMGSLISLAAPQIM-----------------TTLQTMLV 541
gi 302693825  430 wLKNKMLGVISCVGNMLqdKSGKkTAEQKRMILRGLGAFISRVGPAIRHIAPQIM-----------------ACYQSVIS 492
gi 299748269  818 FLATQMLGIMSKIIDTLqdVHGKkSVEAKEQIIRSIGVFISLVGPPIHSLSSQIM-----------------AIFQTSLS 880
gi 353242301  601 FLQQHIMAIVTHLNNELqdVHGKrSVDTKQWVLYGLRRVMMLIGESIAVVAPQVSfssyrsyqganisqklvAIMQNTIR 680
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|..
gi 75252859  1175 KETLQMDGLDVLHFFIKRLaevSCTSIKYVMSQVVAAFIPSL 1216
gi 336373879  540 IPELSEVTLATWFTFLSTL---EPNEVGPHVGPTSASFISSW 578
gi 449549539  536 IQELVDATLESWFTFLTTL---ERRDIGPHVGPTSAAFVAFW 574
gi 215472508  195 IPDLADATLTSWHCFLVTM---SPEEVGPHIGPASAVFMAFW 233
gi 568442725  529 VPELSEVTLQSWHKFLTTL---EPGEVGPHVGPTSAAIVTAW 567
gi 443917690  939 IPELSEATLSTWHSFIETL---LIVDAVSLLGVTTATVVRHW 977
gi 527297949  542 NPDFTDVTLRSWREFLATL---DVQDLGPYVGPTSAFFVMKW 580
gi 302693825  493 APELTEATLESWLIFLQTL---EWADIGEVVGTTSSTFVLNW 531
gi 299748269  881 VAELAEVTLESWHEYLVTI---DSKDLGPHLGSTCSAFVSAW 919
gi 353242301  681 IAGLTSVTVEVWQEFASIM---SISDFGPYVPLTSAIFVASW 719
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