Conserved Protein Domain Family
PMC2NT

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pfam08066: PMC2NT 
PMC2NT (NUC016) domain
This domain is found at the N-terminus of 3'-5' exonucleases with HRDC domains, and also in putative exosome components.
Statistics
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PSSM-Id: 336915
View PSSM: pfam08066
Aligned: 149 rows
Threshold Bit Score: 48.7025
Threshold Setting Gi: 1028575810
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 122093955    54 GMKSVLALPs--G---NS-RDLYDTH-PSFVRIMDTQANKVLHMISDVLKLHEIKGNIvvrd---------reeKFELLQ 117
gi 74997361     32 AAKLSNNLPs--E---ED-YSYYETF-PEFKLKMNSLGKRLLNLAQNFVQSENPKSDLsltdtnd---vddlsdRFSGIV 101
gi 762096277    34 ATRVSNNLP---Aa-gDD-YDYYSSF-QGVRDILDIEGKRVLNIIQNVLRYHNVKGNMtsssea-----tdlddKFDVLM 102
gi 470243986    47 AIKISNQLPi--D---ED-YSYYSTY-PAFREKMNQFGRRLLNLTDNFVQSENPKHSPlfdtndne-dvedvseRFTNIV 118
gi 1160573049   51 AIKISNQLP---Ve--ED-HSYYSTY-PAFKNKMNDFGKRLLNLTQNFVNAEDPKNQDnlfsnidvddvdeiseRFPSIV 123
gi 1032726869   13 GIKASNSLP---S---ADnFNYYTCF-PTFNEIRNEQIKKILNSMQGIVERAGIAGNIkqrd---------ieeKFDLIL 76
gi 674592863    26 AVRLSREFP---TistPS-FAYYRGd-PKYNAVMNANSNKIESMIQNGFDMIDGNVNImdlhks-----ksleeKFTSIV 95
gi 514686575    40 AVKASVQVPk--G---DD-HLYFSTI-PEFKTKTRDLQQRLLRQIEGLAKLEHGHLEGwsrd--------dmdeQMSYLT 104
gi 674576004    29 AVKFSHEFPtnsT---PA-YTYYNDF-AEYRAVMNGNSSKILTTIQDVIDELDGKANImdapqp-----ksleeKFNTIV 98
gi 752883162    24 GIKAANNLPa--T---DN-FNYYVCLkPSLNEARNKDLRRILATMQMIIRTTGGSSNIesad---------vddKFDLLL 88
                           90
                   ....*....|....*....
gi 122093955   118 EFNDSMLERINSNLDEVAG 136
gi 74997361    102 DIVDGMIDKVDKTIDPkyn 120
gi 762096277   103 DANDHILEKVGSFLDESAG 121
gi 470243986   119 EVVDGIIDKVDHLTDQMDK 137
gi 1160573049  124 DVVDGIIDKVDNFTDRLDK 142
gi 1032726869   77 ESNDIYLDQAGLCMDEASG 95
gi 674592863    96 SANDRIIDRLNAAMDEees 114
gi 514686575   105 EINDLCMERVSMFLDDKRG 123
gi 674576004    99 CINDEIIDRVTAVMDKeef 117
gi 752883162    89 ETNDHLLDQANILMDEESG 107
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