Conserved Protein Domain Family
PMC2NT

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pfam08066: PMC2NT 
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PMC2NT (NUC016) domain
This domain is found at the N-terminus of 3'-5' exonucleases with HRDC domains, and also in putative exosome components.
Statistics
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PSSM-Id: 311833
View PSSM: pfam08066
Aligned: 151 rows
Threshold Bit Score: 51.428
Threshold Setting Gi: 313242411
Created: 22-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
5C0W_K         18 VVRAA-SSLA--S--QDVDFYKNLdRGFSKDLKSKADKLADMANEIILSIDEHHESF----ElK---EEDISDLWNNFGN 85
gi 762096277   34 ATRVS-NNLP--AagDDYDYYSSF-QGVRDILDIEGKRVLNIIQNVLRYHNVKGNMT----SsSea--tDLDDKFDVLMD 103
gi 780073132   34 ATRAA-NELP--AagDDYDFYSSFe-GFRQFCNSQGDKLLGNIQRLAGQQGADESQVg---LsKildLED---RIDSLIE 103
gi 156361913    4 GIQKA-NSLPeaG--EDHDFYYSF-SDFREFRKAQGTRILNNVHDLLKQFHVRCRWPnrntScSnvdVDDL---YESLVE 76
gi 196007028    4 ATQCG-NKLPtaG--DDYDFYASY-SSFQQFMQEAGDRLLSLNGALIRHLGLNCRWP----LqSd--AFDIDDRTDSLID 73
gi 260790959   34 ATKSSrTALPspG--DDFDYYSSF-AGFREFAATQAHRIVNNMNALLRHEGVEGEVL----RgKks--vELDDRLDTVVE 104
gi 321468927   26 VTKYS-NELPssG--SDWDYYQSY-PAYASAMKEFGGRITNVMTKIYGHYGLTGKVG----Kl------DLEEQMELVSD 91
gi 675870542   25 srKHV-DSLPvsG--SDFECWTSYd-EFTHLTNHHGKRILNLIQLILSKHNLKTDIS----SeLl----DVEERYDLLTD 92
gi 313242411   31 SIRSS-SSLPsaG--ESYDFYQTY-PAFTSFQRRVNDKIMKIVTDLnalhg--------ratkReplPDD---LVESMLE 95
gi 1043415704  51 ATKAS-TGLPqgG--DEYDFYRSF-PGFRDFCESQGEHLLHCMSQVMQYHGLRSHIrd---rsRvtlLED---KFDLLVD 120
                          90
                  ....*....|....*
5C0W_K         86 IMDNLLEMSDHSLDK 100
gi 762096277  104 ANDHILEKVGSFLDE 118
gi 780073132  104 TNDTLLENAGALLDE 118
gi 156361913   77 ANDTLLEEVDTSLDE 91
gi 196007028   74 ANDAILEKVDLLIDE 88
gi 260790959  105 ANDIILERVGSLLDQ 119
gi 321468927   92 NNDILMERINLSLDE 106
gi 675870542   93 ACDQLMDRIGTNLDd 107
gi 313242411   96 ANDQILEGVGNKLDE 110
gi 1043415704 121 ANDVILEKVgillde 135
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