3JB9,5GAM


Conserved Protein Domain Family
PRO8NT

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pfam08082: PRO8NT 
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PRO8NT (NUC069), PrP8 N-terminal domain
The PRO8NT domain is found at the N-terminus of pre-mRNA splicing factors of PRO8 family. The NLS or nuclear localization signal for these spliceosome proteins begins at the start and runs for 60 residues. N-terminal to this domain is a highly variable proline-rich region.
Statistics
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PSSM-Id: 336921
View PSSM: pfam08082
Aligned: 47 rows
Threshold Bit Score: 189.396
Threshold Setting Gi: 74621958
Created: 24-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3JB9_A         79 KADLPPEHLRKIMKDRGDMSSrkfradkrSYLGALKYLPHAVLKLLENMPMPWEEYREVKVLYHVTGAITFVNESPRVIE 158
gi 122046973   53 KDDVPPEYLRKLMKDNGDLSGksfgterkLCVALLKYMPLALYKLLENMPMPWEETRYVNVVYHMGGVLTLVDDTPTVAE 132
gi 754419915   98 KVDMPPEHLRKIIFDHGDMSSkkfasdkrSFLGSLKYMPHAILKLLENMPQPWEQTKEVKVLYHITGAITFVNEIPRVIE 177
gi 330799836   38 KEDMPPEHLRKIIKDHGDMSNrkfkddkrVYLGALKYMPHAILKLLENMPMPWEQVKYVKVLYHLSGAITFVNEIPLVIE 117
gi 254572423  137 KIEMPPEHLRKIINDHGDLSSkrfdkdkrAYLGSLKYLPHAILKLLENMPQPWEETKQVKVLYHTTGAITFVNEIPRVVE 216
gi 927372991  121 KIEMPKEHLRKILNDQGDLSSkkfsqekrSILGSLKYMPHAVLKLLENMPQPWEAVKEVRVIYHQSGAITFVDEIPRVIE 200
gi 123976938   38 akELPPGHIRQIMTSHGNMSHdkfagqkrLYIGALKYAPHAVLKFLENMPMPWEELRKVRVLYHTAGALTFVNEVPRVVP 117
gi 501754129   72 KADLPPEHLRQIMRMHGDMSSkkyrhdkrSYLGALKYMPHAVLKLLENMPMPWEDVREVPVLYHITGAITFVNTVPRVIE 151
gi 149238566  201 pmEMPPQHLRKIISDHADMTLlkvtsdkrSHLGSLKYLPHALFKLLENIPHPWELSKEVKVLYHRTGAITFVDQSPRVIE 280
gi 398023633   63 KDLMPPEFIRKVVKDNGDLGGkrfkserkLCVGMLPYIPLALLKLLENMPMPWEEARYVTVVYHVGGVLTIVDDTPTVAE 142
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
3JB9_A        159 PHFIAQWGTMWMMMRREK----RDRKNFKRLrFPPFDDEEPP-FS-IdQLLDLEPLEAIRM-DLDeeddAPVMDWFYE 229
gi 122046973  133 QLYLAQWGSMWTRMRSHKvelqQEGGAFRRM-IHKGNENEPP-IEyGdYIMDREPPEAVHD-ELDeedsAAIIDWFYD 207
gi 754419915  178 PIYTAQWASMWIMMRREK----RDRRHFKRMrFPPFDDEEPP-LDwNeNLQDLEPLESIQL-ELDevddEHVIDWFYD 249
gi 330799836  118 PVYISQWATMWVTMRREK----RDRKHFRRMkFPCFDDEEPP-LDyAdNILDIEVEDPVQM-DLDenddEAVIDWFYD 189
gi 254572423  217 PIYTSQWATTWLMMRREK----RDRKHFKRMrFPPFDDDEPP-VDwGeNIQGVAPLDSIQI-DLDevddKAVIEWFYD 288
gi 927372991  201 PVYIAQWATMWLQMRREK----KDRRHFKRIkFPVFDDEEPP-INfSeNIEDLEPLDAIQM-ELQdvedLPVADWIYD 272
gi 123976938  118 PQYLAQWAETWIAMRREK----RDRHQIRRLrFPPFDDEEQP-LDfVtNIEGVEPPEAILM-ELDededAAVYEWFYD 189
gi 501754129  152 PLYIAQWATMWIMMRREK----RDRRHMRRIrLPPFDDEEAPlLEqAqEMAELEPPEPIQM-EFDpeedSAIAEWFYD 224
gi 149238566  281 PVYIAQWATVWELMRKEK----RDRKHFKRMqFPPLDDEEKF-LSwIeNFDDADLPDAIQStELea--dQFVGDWIYD 351
gi 398023633  143 PLYVSQWGSMWTKMRANKvellQEGGGFRRA-VHKGDENEPP-LDfAdYLMDRVPPPPVLD-DLDeednASIVGWFYD 217
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