Conserved Protein Domain Family
DUF1708

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pfam08101: DUF1708 
Domain of unknown function (DUF1708)
This is a yeast domain of unknown function.
Statistics
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PSSM-Id: 311853
View PSSM: pfam08101
Aligned: 67 rows
Threshold Bit Score: 306.494
Threshold Setting Gi: 367009532
Created: 25-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772   44 VAPEEVHELLRGCTQELKARALHTPFLLLPFRPSSDASAARTFVRNYFSqsvErgspLNGEALA-QELRL---TDPLVLC 119
gi 74695752   154 gTGSNSTDMIRAAMEIFKPN--------LSHYSFSETQQIRQLLASFFPrag---ctLAGTALR-EAIERefrNNWNRLI 221
gi 294656575   34 FTRKKLRGILHLITGELKSRGTKTPHIFLPFRSRIDDTKLELFISKIFPrgeLig-mYDEIEVV-EILRK---FDEFTLI 108
gi 150866241   34 FSKRKLKSILHLITAELKARGTNVPHILLPFRSKINDSKLEQFLEQLFPngeLidvdHDENHAL-IIIQS---YDEFTLI 109
gi 754408180   59 FSRTDVRELIHTVTQELKIKGNKTPLVLLAFRPKVDDSKLTTFLSLVFPngtTpa---piNQIE-RAVRD---TDEYTLM 131
gi 260942605   26 LSRKRLQALLHAITGELKARGTRTPHVFLPFRSRIDDTKLEMFLRTVFPhg-----qYAGDAVL-GAVKD---FDEFTLV 96
gi 190348205   35 FSRRNLKTILHLITGELKSRGTKTPHVFLPFRSRIDDHQLELFLQASFPggtVa----sEEVLR-RIVKE---YDEFTLM 106
gi 444315257   97 FTWEVARTPIHWLTIELKRRAKTTKNLLLPFRSPQDNTNLVYLLTILFPnesIpdsqLTEKEII-GHINK---NNVWTLI 172
gi 156840694   52 FEFEEVHDVIHFLSSELKSREFDRTLLLEPLNSD-NTDNLNDFLTGIFKln----lsLEGGELRwSSLVK---ANSFTLF 123
gi 45184896   154 gTGSNSTDMIRAAMEIFKPN--------LSHYSFSETQQIRQLLASFFPrag---ctLAGTALR-EAIERefrNNWNRLI 221
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  120 GVLKWCWSRLP-G-G-VVTWEAYELFKvgeqDSQFAPDAFSTFIPISVDSDARSQIIFDFFDLLTAIAAHGKSNGLGGRK 196
gi 74695752   222 LALRILWAELP-E-S-IVPWDCFITFKrleeRDGYPTSAFFMLLKQVLPSHDYMCTTYAFLEILVTIVG---RTDLLVEK 295
gi 294656575  109 CGLKYLWSRLP-N-NeIIGWDVYLEYKrkekEAGYPKGAFLSIMPKCLSSPAHASIVYDFLDLLISIASNSQYNYLSGRK 186
gi 150866241  110 CALKYMWSRLP-N-NeIIGWDVYLEYRrrerEAGYPKNAFLSIMPKCLSSPAHASIVYDFLDLLISITSNSQYNYLSGRK 187
gi 754408180  132 AALKYLWSRLPmD-S-IVGWDAYETFKkleaRSNYPKKAFLEFMPQCLTSPAHASIVYDFLDLLVSLSANAKENQLSGRK 209
gi 260942605   97 CGLKYLWCRLP-N-NeVIGWKVYLEFRrrehEAGYPKDAFLTIMPKCLSSSAHASIVYDFLDLLISIASNSQYNHLSGRK 174
gi 190348205  107 CAMKYLWSRLP-N-HeIIGWDVYLEFKrkeeEQGFPRTAFLTIMPKCLSSPSHASIVYDFLDLLVSIASNSQYNYLSGRK 184
gi 444315257  173 QCLKYIWCRLP-NgG-ILHYKQYLKFKkdelSNELPNDSFFNILPKYLDGKDQASIVYDFFDLIKIITSNGFITNINSID 250
gi 156840694  124 QALKYIWCRLP-N-GgVIGWDSYKLFKvkekKKNYPTRAFLEIVPESLTSYAHNSVVYDFFELILTFTS---KTGLHTTQ 198
gi 45184896   222 LALRILWAELP-E-S-IVPWDCFITFKrleeRDGYPTSAFFMLLKQVLPSHDYMCTTYAFLEILVTIVG---RTDLLVEK 295
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  197 LSRY-----AGWWAF---------------E---HT-------------D---------T-------------GNGFEAA 218
gi 74695752   296 TTQMdliftAGQVCFpsckaveeykdandeG------------------------------------------NDDELIL 333
gi 294656575  187 IAKM-----SSLWAF---------------N---GStkphqspfydatlS---------K-------------ENTFIDG 221
gi 150866241  188 VTKM-----ASIWAF---------------N---PT-------------S---------KlsksafydatinqEFNFIQG 222
gi 754408180  210 ISKM-----AGLWAF---------------H---GPpnsanl-tksrldP---------T-------------ENSFREG 243
gi 260942605  175 VAKM-----ASLWAF---------------NvapHS-------------DsafydataiR-------------ENTFLDG 208
gi 190348205  185 IAKM-----SSLWAF---------------N---PArermksafydatiD---------R-------------DHSFIDG 219
gi 444315257  251 TCKI-----YGIWCFgglndcifysgedtaE---HT-------------S---------Ksvn--------ssNSPLEIG 292
gi 156840694  199 IAYI-----FSLWAF---------------E---YP-------------S---------Qykdgf---qkqilTNSISSG 230
gi 45184896   296 TTQMdliftAGQVCFpsck--------aveE---YK-------------D---------And---------egNDDELIL 333
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  219 YKNWSTAADATSHLFFAYLRSLSPEt-RGMggiST-LPIALQTLVQATEYPPETPTllq------vstTKVVMIVDTVSP 290
gi 74695752   334 NKIYRNRGSALYHLFVAYLRSLADK--------GKiKDFYLLDNFDVHEYPP-GPYrpmtqraltltvPRF-IPESDMRN 403
gi 294656575  222 LEYWKPSSEALFHLLLSFLRAMLPDneSDT---LK-LPKTLQSLLITNSYPPLENTdsiks---iitiPCVVIKSTKVSS 294
gi 150866241  223 VEAWKSSGNALFHLLLSFLRAMLPEndAET---LK-LPKALQSLLITTAYPPSEDTgrtlk--smitiPCVVVKSTRPSS 296
gi 754408180  244 LRDWLPAADALFHLFLSFLRSMLPDdqNTK---LQ-LPRTLQALLASNSYPPP-DLtfqss--tlvsvPLVTIRSNTLSK 316
gi 260942605  209 LDAWKLHCNGLFHLCLSFLRAMLPDteSDT---LN-LPKTLQSLLVTSSYPPP-DNapstk--sviviPCVQVRTTVPCS 281
gi 190348205  220 LDRWKQSSGALFHLLLSFLRAMLPEndMDT---LK-LPKTLQSLLISNSYPPLANNdsvks---mikiPCVLLKSTKPSE 292
gi 444315257  293 IEGYFKIANALFHLYLSFLRHFTKNgiKKT---SS-INNELKKLLIDYDYPPI--Dfkins--nlitiPLVQLHTPVPSD 364
gi 156840694  231 FESWIPGADATLHMLLSFLKIYVSQnlQK----SK-ISGTEIQFLLNSEYPPLEIKetikk--shrtiPLVTLKALN-CK 302
gi 45184896   334 NKIYRNRGSALYHLFVAYLRSLADKgkI--------KDFYLLDNFDVHEYPP-GPYrpmtqraltltvPRF-IPESDMRN 403
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  291 TPFALLRRAKN-----------FEYRDSDHHLQEFA-----S-FEDPLRALTDECVRVLKCISstnqssvtd-------p 346
gi 74695752   404 DFNQLIKFVAKagsriyssqhaFSKLEN-SFLDKFEe---nP-LKVVEGLFSKSSKRYLYKFDkhfstnyfktlndrqgw 478
gi 294656575  295 NVYELLSKVRNtisfs--kkdsFLSMENYTILKNIFqk--sS-TNEIVSSLTEESRRILTRLN----------------- 352
gi 150866241  297 NVYELLSKVRHtlsfd--kkdaFLSIENYTILKNIFk---kDsTDDIVRGLTEESRRVLGRLT----------------- 354
gi 754408180  317 NPTELLNKLPKvlsfd--nqkrFEAKEDYALLKSLCr---nD--SNIMNKLSGESRRIIGLLCk---------------- 373
gi 260942605  282 DPYELISKVRHtlrfd--rkddFLSIENYTILKSIFqk--gS-TNEIVDTLTEESRRVLTRLCa---------------- 340
gi 190348205  293 NVYELLSKVRRtikfd--kkddFMSVENYTILKNIFk---kDsTADIVASLSEESRRIMGRLT----------------- 350
gi 444315257  365 DLWQLLNRCKMnlnlnfdnpdlFKSRENFALLKILFkn-lkD-IKDLNNSFTEDTENNVKSLTtrhs------------- 429
gi 156840694  303 TAISLLRRCAKlldfs--nndnFEAYEDYVILKSIFksssnK-HFDIRKMLTHESLLTYNFLTdnp-------------- 365
gi 45184896   404 DFNQLIKFVAKagsriyssqhaFSKLEN-SFLDKFEe---nP-LKVVEGLFSKSSKRYLYKFDkhfstnyf--------- 469
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  347 tssaqdaSWSRFEDMGFGSTldtdleedrksaslarrefggglksapqsgagdlgRPTTPSWADFms------------- 413
gi 74695752   479 nralhelDPTN--------------------------------------------QYAVSTWIESckqhgfseflsmled 514
gi 294656575  353 -------SDPIDSNYDLYPG-----------------------------------------WSKp--------------- 369
gi 150866241  355 -------DDSIESKYELYPG-----------------------------------------WPK---------------- 370
gi 754408180  374 ----------KPSEGTLMAG-----------------------------------------WPEYhp------------- 389
gi 260942605  341 --------PPIDSEFNLYPG-----------------------------------------WVK---------------- 355
gi 190348205  351 -------DISDSSDYDLYPG-----------------------------------------WAPF--------------- 367
gi 444315257      --------------------------------------------------------------------------------
gi 156840694  366 --------------------------------------------------------------nnFls------------- 370
gi 45184896   470 ktlndrqGWNRALHELDPTN-----------------------------------QYAVSTWIESckqhgfseflsmled 514
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 121741772  414 -----------sgFsdenpfkapvtpvllppdkvlppiamdrgQSSQSHKrNldsePSIDPGELASITTLDLDDSFWWVW 482
gi 74695752   515 nmggegtlalghpL-----------------------------LASLTEElSfnakEEEEELAAVRLSKMGVSEWFISSW 565
gi 294656575  370 ---------------------------------------------------DlvtdPNIPLFSQINIEDVSLQDYYIWTW 398
gi 150866241  371 ---------------------------------------------SQPei-----dDNIPLFSQVSVYDVTLQDFYIWTW 400
gi 754408180  390 ------------------------------------------------------peTVVENKIQVSVSRVSIDDYFIWTW 415
gi 260942605  356 ---------------------------------------------------PdkidTDIPMYSEVSISNVTLQDYYIWTW 384
gi 190348205  368 --------------------------------------------GGKVDE-NiplfTEL------TIQDVTIQDYYIWTW 396
gi 444315257  430 -----------------------------------------tlntNWPHSkYvsekNTIQFDDYLQIKNVEIDKTFYWSW 468
gi 156840694  371 -----------gwV-----------------------------SQDQKDNiEfvkdE-------VIVERIDIADYFPLVW 403
gi 45184896   515 nmggegtlalghpL-----------------------------LASLTEElSfnakEEEEELAAVRLSKMGVSEWFISSW 565
                         570       580       590       600
                  ....*....|....*....|....*....|....*....|...
gi 121741772  483 ISSLAGEEPVSRKAVFGR---CALLETVI-K-N-TKWLVLEEQ 519
gi 74695752   566 KYEM----------FLGKiynTLVIKLTKrV-GdCDWIVISTD 597
gi 294656575  399 LSSLASDQTSHNKKLFGR---SIVVEASL-K-GfQKWLIITEQ 436
gi 150866241  401 LSTLGSDQSTEFKKIFGR---SLVMESDL-K-GfQKWIIISEQ 438
gi 754408180  416 MSSMSFEETQSKKKLFGR---SLISEFVF-D-GfKKWIVVEEQ 453
gi 260942605  385 LSSLGSDQTVSTKALFGR---SIVVEAGL-H-GfQKWLIISEv 422
gi 190348205  397 LSSLGSDQHSIVKRNFGR---SLIAEVEV-L-DqRKWIVVSEQ 434
gi 444315257  469 LSTLSNEQSNKKKSLFGR---CVLLEFNIsN-NlNKFIFFEDt 507
gi 156840694  404 ESSLSYEQTIEKRSLFGK---ILLLEFKF-D-QfTKWVAFQav 441
gi 45184896   566 KYEM----------FLGKiynTLVIKLTK-RvGdCDWIVISTD 597
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