4XOI


Conserved Protein Domain Family
Anillin

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pfam08174: Anillin 
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Cell division protein anillin
Anillin is a protein involved in septin organisation during cell division. It is an actin binding protein that is localized to the cleavage furrow, and it maintains the localization of active myosin, which ensures the spatial control of concerted contraction during cytokinesis.
Statistics
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PSSM-Id: 336950
View PSSM: pfam08174
Aligned: 86 rows
Threshold Bit Score: 53.0511
Threshold Setting Gi: 398405514
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4XOI_B         89 SKGsVTLSEIRLPLKADFVCSTVQK--PDAa---------NYYYLIILKA-GaE--NMVATPLAs-TSNSLn-------- 145
gi 171685802 1061 PKT-SAFSRVFASPKKRKEMELRQRqaEEEerla--aqreAQA-----RQmK-S--QPTAWDLLs-PLAADdgsfarayv 1128
gi 367050428 1056 PKT-STFSRVFASPKKRREMELRQKqqEEEerala-aqreAQA-----RQlK-AaqQPTAWDLLs-PLAAEdgsfarayv 1126
gi 336271601 1087 AKT-STFSRVFASPKKRREMEMRQK--EEEerlaq-qqreAAA-----RQmK-T--QPTAWDLLs-PLAAEdgsfarsyv 1153
gi 380493604  534 PKT-STFSRVFASPKKRKEMEMRQR--EEEerlaaeqqkaAQA-----RQmK-V--APTAWDLLs-PLAAEdgsfarsyv 601
gi 399171340 1071 TKT-STFSRVFASPKKRREMEQRQK--DEErqq-----seALA-----RQrS-R--APSAYELLs-HLTADdgsfgrsyv 1133
gi 154274163  354 HKT-STFSRVFASPKKRKELEQKQQ--LEAqqlkq--------rkaeeKAlA-E--KKNPLDALr-HLVASdgsfarayv 418
gi 295660196 1102 FKG-STFSRVFASPKKRKELEQRQQ--FEAqqlkq-----------qktdeR-AldKENPWNALr-PLVASdgsfarayv 1165
gi 258574221  990 QKT-SAFSRVFASPKKRREMELRQQ--MEAqqlkqkteekILA-------------GPDPWAKVr-NLVAKdgsfarayv 1052
gi 398405514 1144 GKT-SSLTRFLASPKKRAAEKERLE--REAadaenrrrdeEEARLQQRKRqS-A--HPSAWDLLhtLVNPAdgsfarayv 1217
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4XOI_B        146 ----GDALTFTTTFTLqdvsndfeiNIEVYSlVQKKDpsgldkkkKtsk---skaITPKRLLTSITTksnihsSVMA--- 215
gi 171685802 1129 clkdHESKCFGRPYLV---------DVAAFNeWAMED--------Agfa---ssvKSKR---GNMGPg----sVVRR--- 1178
gi 367050428 1127 clkeHEPRCFGRPYTV---------EVAAFNeWATEE--------Agfa---ssvKSKR---GNAGAgg---gVIRR--- 1177
gi 336271601 1154 clkeHESRCFGRPYTV---------EVAAFNeWATEE--------Agfa---ssvKSKR---GSTGP-------VRR--- 1200
gi 380493604  602 clkeHESRCYGRPYVV---------DVACFNeWATEE--------Aafa---ssvKSKR---GNTAV-------VRR--- 648
gi 399171340 1134 clkeHEHRCFGRPYMA---------EIACFNeWAWEE--------Asfa---ssvKSKR---GTAAAg-----VVRR--- 1182
gi 154274163  419 slsdYEKAAFGRPLTV---------DVTCFNeWATDP--------Vnn------sKNKRSMANSAGSg-----MQQR--- 467
gi 295660196 1166 slsdYEKAAFGRPLTV---------DVTCFNeWASNP--------Vkn-----nsKNKRYMVHSSGSgs---tMQKQqqq 1220
gi 258574221 1053 clgdYEQHAFGRPLTV---------DVACFNeWAVDE--------Ipast--nnsKNKR---NTVALg-----VQRR--- 1102
gi 398405514 1218 nlraHEKQCFGRPLVV---------DIPCYNeWAIDA--------EsgssnntsvRSKR---GTTGP-------VRR--- 1267
                         170       180
                  ....*....|....*....|....*.
4XOI_B        216 --SPgglsavrtsnFALvGSYTLSLS 239
gi 171685802 1179 --AP----------YKI-GKLELQLL 1191
gi 367050428 1178 --AP----------YKI-GKLELQLL 1190
gi 336271601 1201 --AP----------YKI-GKLELQLL 1213
gi 380493604  649 --AP----------YKI-GKLELQLL 661
gi 399171340 1183 --AP----------YKI-GKLEVQLL 1195
gi 154274163  468 --PP----------YKI-GNLELQLL 480
gi 295660196 1221 ylPP----------YRI-GNLELQLL 1235
gi 258574221 1103 --PP----------YRV-GNLELQLL 1115
gi 398405514 1268 --PP----------YIV-GHLELQLL 1280
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