Conserved Protein Domain Family
SYF2

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pfam08231: SYF2 
SYF2 splicing factor
Proteins in this family are involved in cell cycle progression and pre-mRNA splicing.
Statistics
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PSSM-Id: 336966
View PSSM: pfam08231
Aligned: 105 rows
Threshold Bit Score: 78.3849
Threshold Setting Gi: 67466483
Created: 28-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74951784   402 LISPNTSYPYIISAGMVE-KL-----SKIEK----T-KeknktfGWNiFNQDALYRAHKKRLRETGF--NPDLYEKQKNE 468
gi 75015616   532 NNNNRRDKLYNTSAFHVK-KI-----MHKKN----K-K------KDDtYELENDTNLYKKIKFNFSI--NRKIYDEKKKI 592
gi 74989001   437 EQAEERNYVYNTSAIKAY-NS-----ISKKK----K-K------KMEaYELDNDINLYKKIKFNFSI--NRKIYDEKKEI 497
gi 74854197   135 GLDPQKERLKNQIAEEI--KP-----NKKEK----K-KdsivkdksntYSDEHVYNSYKKRVKEMEKfhNSEHFKKVVSN 202
gi 1160575043 136 GGDPEREKLKNALASDLE-NK-----AKKKGnkkfE-Gvhn------kqSDSHIYNSYKKRVKEMESfrNSEHYKEFVDK 202
gi 927376757   67 GVNSERLRNLRYTIEQDE-AW-----HAKLE----AgKtaaedrEFQ-NFKQLARQTYTKGLKNLNPl-KSEQYEAQKQI 134
gi 330791325  136 GLDPEKEKLRNIVADDIK-TK-----KKTGK----K-Ydk-----dS-YTDEHVYKSYKKRVKEMESfhNSEHFKPVVSD 198
gi 67466483    24 kvDCKKPK---FTKNESTdSWmdmpaNTLKH----K-Kdindq---kgdlAKQAYSAYERKIRWLNPkdTEKEYQQYKQN 92
gi 901875389  445 DDGEDPPAIYTTSAAQAK-GA-----SKKKN----K-K--------DlLEVDRDSRFFKKMKFNFSI--NRNLYEEKKKK 503
gi 221052146  454 dDKEDAPAIYTTSAAQAK-GA-----SKKIN----K-K--------ElIEVDRDKRFFKKMKFNFSI--NRNLYDEKKKK 512
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74951784   469 LGE-EFYRPGiv-------nfNPNEASKDVVVRNVEKQYKKRDAFSRRRLYDdEAQDISYINERNRVFNKKLERSFGTYS 540
gi 75015616   593 HGS-NFYNINllnh----entKANEYDKNKVVEFCKKQEELRSKMSRKRKEK-EGIFKNYINQRNKIYNKKLDRYFNKHT 666
gi 74989001   498 YGK-NFYGNNllih----dntPCSDKDKNRIIEFCKKQEELRSKLSRKRTND-NEIFKNYINRRNKIYNKKLDRYFNEHT 571
gi 74854197   203 EDVkesgdsinnnkyeygksiEIPRDNINAMKQELLKNQENRRSFKRKSFK--EEEDINYINEENRLFNQKVSRAYDKYT 280
gi 1160575043 203 DQInNetey--------gkhgFVPEANVNAMKQELLKHQMERRNNFKKRGTN-PDEDVSWINEQNRVFNKKVSRAYDKYT 273
gi 927376757  135 YAEmKKEGKSdsei----issLTSREKLNQMVDQLKERE--TTTVKRRKTAQ-D--RQNFINDKNKQFNDKLDRHYDEYL 205
gi 330791325  199 SSEsL----Etvey---gkssVVPRGNINAMKQELLKNQEQRNSFKRK-GIN-DEEDVNYVNESNRIYNKKVSRAYDKYT 269
gi 67466483    93 DQLrqki-----------qsgYVSPEKIDCLQKQLARGKKEAQRFHRERKE--KSFQRDYINVNNKKFNEHVNQAYDQYT 159
gi 901875389  504 LGE-SFYGGDllat----dssKCTESDKNKVISFCRKQQVVRSKLSRKRQHE-DGLFKNYINRRNKMYNRKLDRYFNQHT 577
gi 221052146  513 MGK-SFYGQDllit----dtsKCTERDKNNVISFCRKQEMVRSKLSRKRKED-NGVFKNYINKRNKMYNKKLDRYFNQHT 586

                  ....*...
gi 74951784   541 NEIKQNLE 548
gi 75015616   667 LEIRNKLE 674
gi 74989001   572 AEIRRNLE 579
gi 74854197   281 VETRQNLE 288
gi 1160575043 274 LEIRQNLE 281
gi 927376757  206 SDLKESiq 213
gi 330791325  270 LETRQNLE 277
gi 67466483   160 SDIKDALE 167
gi 901875389  578 AEIRQNLE 585
gi 221052146  587 AEIRQNLE 594
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