3VZ9,2VE7


Conserved Protein Domain Family
Spindle_Spc25

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pfam08234: Spindle_Spc25 
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Chromosome segregation protein Spc25
This is a family of chromosome segregation proteins. It contains Spc25, which is a conserved eukaryotic kinetochore protein involved in cell division. In fungi the Spc25 protein is a subunit of the Nuf2-Ndc80 complex, and in vertebrates it forms part of the Ndc80 complex.
Statistics
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PSSM-Id: 336968
View PSSM: pfam08234
Aligned: 146 rows
Threshold Bit Score: 39.0749
Threshold Setting Gi: 74608166
Created: 27-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3VZ9_B         28 IHNEQLQFIFRHiDHKDPD-KPYMFTLSINEQgD---YE-VTSCTPPLDC--ISEFQLKVRET---NNFSAFIANIRKAF 97
gi 74621473   176 MRENVIKVVFSRiCPEDSV--ECFVTLDLSAD-Gp-----VVDLFPR--MygLERANSLFREH---NNFHDFLRVIRSGF 242
gi 675884050   65 ntEQIIEIRFTNiNKNDPQ-KEFVLALNVGYS-----FT-VKRCCPKIEk--IDKLLLTLNLT---ADWHSFVVSVRKHF 132
gi 1005958221 135 eEPSKFKIGFSHiDPDDAE-KIFSVTIDIKLG-T---IK-VLEVDT--AEeeFKELEKWFNEKfavINLPIFVNRARKIF 206
gi 674571579  164 rnHNNVQVVMRGcCEDDYD-LLSYVILRFNAD-St-pME-LIKCNPPVt--dVEKLVEHFNKA---GDFRSFLLVLRDRF 234
gi 667636465  161 ICDNMLKIEFFNfDETDLG---GYIVMDFKDD-T---ES-VTEVWPCVv--sLEKINLVLNIS---DDFYDFLKRVRGIF 227
gi 817546081  163 VEGNKIKVLFNKfCKDETF--ECYVVLDLSDG-----YN-IIDIYPK--VinIERYSTNLKDK---TRFFELIQDVRKIF 229
gi 674595859  139 kRHHNIQIIFSGcCEDAYT-RLSYVVLRLKSE-AsncMAqLVECNPP--IkdIEKLVEYYNIS---DNTRNFLLILRQRF 211
gi 159111162  156 RDENSIIVIFWGlNPADES-QQYSFRLITRED-Ge-----IIIEDPTIEIanLDLFLSDAKIT---GNIPLLIRRIRLSF 225
gi 357605556  134 nDNQVIFVQFFTeSKKDNEnYSVRLIRNIKNG-K---YE-LLSVNPK--LkcLKELQKEMCDT---NNVPGVLCALRQAF 203
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