Conserved Protein Domain Family
TF_Zn_Ribbon

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pfam08271: TF_Zn_Ribbon 
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TFIIB zinc-binding
The transcription factor TFIIB contains a zinc-binding motif near the N-terminus. This domain is involved in the interaction with RNA pol II and TFIIF and plays a crucial role in selecting the transcription initiation site. The domain adopts a zinc ribbon like structure.
Statistics
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PSSM-Id: 311946
View PSSM: pfam08271
Aligned: 59 rows
Threshold Bit Score: 33.4354
Threshold Setting Gi: 723586688
Created: 19-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
1VD4_A        15 FKCPVCSS-TFtDleanqLFDPMTGTF-RCTFChTEVEEDESAMPKKDAR 62
gi 74579501    4 LKCPVCGN----------EYDINRSNY-LCDKC-GNILE-VIHENDFVKE 40
gi 74565307    1 MVCPKCGS-RDiV-----LLPTN--EY-VCKKC-GYKWPMPQPDYMWIET 40
3WWL_A         3 GTCPECGA-EL-R-----LENPELGELvVCEDC-GAELEVVGLDPLRLEP 44
gi 81342315    5 YKCPNCGS-DM-------AFDSETGSL-SCSSC-GRQDNIESLPKENIAA 44
gi 549038    122 YMCPICLT-KYtQleavqLLNFDRTEF-LCSLCdEPLVEDDSGKKNKEKQ 169
gi 182701396 113 YVCPKCGT-RY-T-----VDEAENNNY-TCEVC-GEVLEPFDNTHRVEKL 153
gi 182702114 115 FFCPNCNV-RF-T-----FEEAMDYGF-SCPGC-GNMLQEFDNSELIKDL 155
gi 74513637  118 YICPNMCVkVS-------YNDAMELNF-TCPRC-GAMLDYLDCSKAIEKI 158
gi 74561661    3 IQCPFCG--AK-Y-----EAPPGRGFY-VCPYC-GTVISEGRTFENVYIF 42
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